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Phellodendrine chloride/盐酸黄柏碱
Phellodendrine chloride/盐酸黄柏碱
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货号：A696868
同义名：
Phellodendrine (chloride)
Phellodendrine chloride是从黄柏树皮中分离纯化的天然产物，具有抗肾炎作用，可能通过抑制小管中的巨噬细胞和细胞毒性 T 淋巴细胞的增殖或迁移起作用。还通过调节 AKT/NF-κB 通路抑制 AAPH 引起的氧化应激。
Phellodendrine chloride/盐酸黄柏碱 化学结构
Phellodendrine chloride/盐酸黄柏碱 3D分子结构
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Phellodendrine chloride/盐酸黄柏碱 纯度/质量文件 产品仅供科研
货号：A696868
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产品说明书
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Phellodendrine chloride/盐酸黄柏碱 质控信息
Phellodendrine chloride/盐酸黄柏碱 生物活性
描述
Phellodendrine HCl, an isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendri chinensis cortex. Phellodendrine inhibited AChE activity in a dose-dependent manner with IC50 of 36.51 μM[2] [3] [4]
Phellodendrine chloride/盐酸黄柏碱 参考文献
[1] Jiang XY, Zhang HF, et al. [ILs-HPLC simultanesous determination of five alkaloids in phellodenddri chinensis cortex] . Zhongguo Zhong Yao Za Zhi. 2014 Oct;39(19):3808-12. Chinese.
[2] Kim YJ, Lim HS, Kim Y, Lee J, Kim BY, Jeong SJ. Phytochemical Quantification and the In Vitro Acetylcholinesterase Inhibitory Activity of Phellodendron chinense and Its Components. Molecules. 2017 Jun 2;22(6):925
[3] Su S, Wang X, Xi X, Zhu L, Chen Q, Zhang H, Qin Y, Yang B, Che N, Cao H, Zhong W, Wang B. Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis. J Cell Mol Med. 2021 Jun;25(12):5707-5720
[4] Li L, Huang T, Tian C, Xiao Y, Kou S, Zhou X, Liu S, Ye X, Li X. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos. Life Sci. 2016 Jul 15;157:97-106
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Phellodendrine chloride/盐酸黄柏碱 实验方案
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总药量计算器
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1mg
5mg
10mg
1 mM
5 mM
10 mM
2.65mL
0.53mL
0.26mL
13.23mL
2.65mL
1.32mL
26.46mL
5.29mL
2.65mL
Phellodendrine chloride/盐酸黄柏碱 技术信息
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