Monomethyl auristatin E | MMAE;Vedotin;Brentuximab vedotin;SGD-1010 | Microtubule/Tubulin

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Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

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临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02227199	Recurrent Adult Hodgkin Lympho... 展开 >>ma Refractory Hodgkin Lymphoma TNFRSF8 Positive 收起 <<	Phase 1 Phase 2	Recruiting	-	United States, Washington ... 展开 >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Ajay K. Gopal 206-606-2037 agopal@u.washington.edu Principal Investigator: Ajay K. Gopal 收起 <<
NCT00866047	-		Completed	-	-
NCT02001623	Ovary Cancer ... 展开 >>Cervix Cancer Endometrium Cancer Bladder Cancer Prostate Cancer (CRPC) Esophagus Cancer Lung Cancer(NSCLC) Squamous Cell Carcinoma of the Head and Neck (SCCHN) 收起 <<	Phase 1 Phase 2	Active, not recruiting	December 2018	-
NCT02623920	Diffuse Large B Cell Lymphoma ... 展开 >> Mediastinal Large B-cell Lymphoma Grey Zone Lymphoma High Grade B Cell Lymphoma Follicular Lymphoma Marginal Zone Lymphoma Small Lymphocytic Lymphoma 收起 <<	Phase 2	Withdrawn(Pharmaceutical compa... 展开 >>ny supplying the drug withdraw financial support. PI has decided to close study prior to enrollment of any patients.) 收起 <<	-	United States, Arizona ... 展开 >> Arizona Cancer Center at UMC North Tucson, Arizona, United States, 85724 收起 <<
NCT02594163	Diffuse Large B-cell Lymphoma ... 展开 >>Refractory Follicular B-cell Non-Hodgkin's Lymphoma 收起 <<	Phase 2	Terminated(Sponsor decision ba... 展开 >>sed on portfolio prioritization) 收起 <<	-	-
NCT02594163	-		Terminated(Sponsor decision ba... 展开 >>sed on portfolio prioritization) 收起 <<	-	-
NCT03474107	Ureteral Cancer ... 展开 >> Urothelial Cancer Bladder Cancer 收起 <<	Phase 3	Recruiting	September 2021	-
NCT03274492	Diffuse Large B-Cell Lymphoma	Phase 3	Recruiting	April 15, 2023	-
NCT02139592	-		Completed	-	Japan ... 展开 >> Osaka, Japan 收起 <<
NCT00866047	Lymphoma, Large-Cell, Anaplast... 展开 >>ic Lymphoma, Non-Hodgkin 收起 <<	Phase 2	Completed	-	-
NCT02191930	Hodgkin Lymphoma	Phase 2	Recruiting	April 2019	Germany ... 展开 >> 1st Dept. of Medicine, Cologne University Hospital Recruiting Cologne, Germany, 50924 Contact: Michael Fuchs ghsg@uk-koeln.de 收起 <<
NCT03264131	Lymphoma Adul... 展开 >>t T-Cell Leukemia/Lymphoma Lymphatic Diseases 收起 <<	Phase 2	Recruiting	January 30, 2026	United States, North Carolina ... 展开 >> Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill Recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Bob Broomer 919-966-9257 bob_broomer@med.unc.edu 收起 <<
NCT03652441	Classical Hodgkin Lymphoma	Phase 2	Not yet recruiting	December 2022	Germany ... 展开 >> 1st Department of Medicine, Cologne University Hospital Cologne, Germany 收起 <<
NCT03356054	DLBCL	Phase 1 Phase 2	Not yet recruiting	June 2025	Belgium ... 展开 >> ZNA Not yet recruiting Antwerp, Belgium Netherlands AMC Not yet recruiting Amsterdam, Netherlands VUmc Not yet recruiting Amsterdam, Netherlands Haga hospital Not yet recruiting Den Haag, Netherlands UMCG Not yet recruiting Groningen, Netherlands MUMC Not yet recruiting Maastricht, Netherlands Antonius hospital Not yet recruiting Nieuwegein, Netherlands Radboudumc Not yet recruiting Nijmegen, Netherlands Erasmus MC Not yet recruiting Rotterdam, Netherlands UMCU Not yet recruiting Utrecht, Netherlands Isala Not yet recruiting Zwolle, Netherlands Spain Hospital Clinic de Barcelona Not yet recruiting Barcelona, Spain Institute Català d'Oncologica - Hospital Not yet recruiting Barcelona, Spain Hospital 12 de Octubre Not yet recruiting Madrid, Spain Hospital Gregorio Marañón Not yet recruiting Madrid, Spain Hospital Clínico de Salamanca Not yet recruiting Salamanca, Spain Hospital La Fe Not yet recruiting Valencia, Spain 收起 <<
NCT02744612	Recurrent Hodgkin Lymphoma ... 展开 >> Refractory Hodgkin Lymphoma 收起 <<	Phase 2	Recruiting	December 2018	United States, California ... 展开 >> City of Hope Medical Center Recruiting Duarte, California, United States, 91010 Contact: Robert W. Chen, MD 626-256-4673 Principal Investigator: Robert W. Chen, MD University of California San Diego Not yet recruiting La Jolla, California, United States, 92093 Contact: Carolyn M. Mulroney, MD 858-822-6600 Principal Investigator: Carolyn M. Mulroney, MD United States, New York Weill Medical College of Cornell University Not yet recruiting New York, New York, United States, 10065 Contact: Peter Martin, MD 646-962-2064 Principal Investigator: Peter Martin, MD United States, Ohio Ohio State University Comprehensive Cancer Center Not yet recruiting Columbus, Ohio, United States, 43210 Contact: Kami Maddocks, MD 614-688-7942 Principal Investigator: Kami Maddocks, MD 收起 <<
NCT03013933	Recurrent Hodgkin Lymphoma ... 展开 >> Refractory Hodgkin Lymphoma CD30-Positive Neoplastic Cells Present 收起 <<	Phase 1	Recruiting	March 2019	United States, California ... 展开 >> City of Hope Medical Center Recruiting Duarte, California, United States, 91010 Contact: Robert W. Chen, MD 626-256-4673 ext 64762 rchen@coh.org Principal Investigator: Robert W. Chen, MD 收起 <<
NCT01290549	Non-Hodgkins Lymphoma ... 展开 >> Chronic Lymphocytic Leukemia 收起 <<	Phase 1	Completed	-	United States, California ... 展开 >> Stanford Cancer Center Stanford, California, United States, 94305-5820 Stanford Cancer Institute Pharmacy Stanford, California, United States, 94305 United States, Florida Florida Cancer Specialists; Sarasota Sarasota, Florida, United States, 34232 United States, New York Roswell Park Cancer Inst. Buffalo, New York, United States, 14263 United States, Tennessee Sarah Cannon Cancer Center Germantown, Tennessee, United States, 38138 United States, Texas M.D Anderson Cancer Center; Oncology Houston, Texas, United States, 77030 United States, Washington Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109 Canada, Alberta Cross Cancer Institute ; Dept of Medical Oncology Edmonton, Alberta, Canada, T6G 1Z2 Canada, British Columbia British Columbia Cancer Agency Vancouver, British Columbia, Canada, V5Z 1H6 Canada, Quebec McGill University; Sir Mortimer B Davis Jewish General Hospital; Oncology Montreal, Quebec, Canada, H3T 1E2 France CHU Dijon - SCE Hemato Dijon, France, 21000 Centre Hospitalier Regional Universitaire de Lille Lille, France CHU Lapeyronie, Hematologie Montpellier, France, 34295 Centre Hospitalier Lyon Sud; Hematolgie Pierre Benite, France, 69495 Centre Henri Becquerel; Hematologie Rouen, France, 76038 Netherlands Academisch Medisch Centrum; Hematologie Amsterdam, Netherlands, 1105 AZ 收起 <<
NCT03729609	-		Recruiting	May 31, 2022	Japan ... 展开 >> Takeda Selected Site Recruiting Tokyo, Japan 收起 <<
NCT01578967	Hodgkin Lymphoma, Adult	Not Applicable	Active, not recruiting	August 10, 2021	United States, California ... 展开 >> City of Hope Comprehensive Cancer Center Duarte, California, United States, 91010 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, North Carolina University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina, United States, 27599 Levine Cancer Istitute, Carolinas Health Care system Charlotte, North Carolina, United States, 28204 Rex Cancer Center Raleigh, North Carolina, United States, 27607 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37240 收起 <<
NCT01771107	AIDS-Related Hodgkin Lymphoma ... 展开 >> Ann Arbor Stage II Hodgkin Lymphoma Ann Arbor Stage IIA Hodgkin Lymphoma Ann Arbor Stage IIB Hodgkin Lymphoma Ann Arbor Stage III Hodgkin Lymphoma Ann Arbor Stage IIIA Hodgkin Lymphoma Ann Arbor Stage IIIB Hodgkin Lymphoma Ann Arbor Stage IV Hodgkin Lymphoma Ann Arbor Stage IVA Hodgkin Lymphoma Ann Arbor Stage IVB Hodgkin Lymphoma Classic Hodgkin Lymphoma HIV Infection 收起 <<	Phase 1 Phase 2	Recruiting	December 12, 2019	United States, California ... 展开 >> UC San Diego Moores Cancer Center Recruiting La Jolla, California, United States, 92093 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein UCLA Center for Clinical AIDS Research and Education Recruiting Los Angeles, California, United States, 90035 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein University of California Davis Comprehensive Cancer Center Recruiting Sacramento, California, United States, 95817 Contact: Scott D. Christensen 916-734-3771 schristensen@ucdavis.edu Principal Investigator: Scott D. Christensen United States, Florida University of Miami Miller School of Medicine-Sylvester Cancer Center Recruiting Miami, Florida, United States, 33136 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Illinois John H Stroger Jr Hospital of Cook County Recruiting Chicago, Illinois, United States, 60612 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Louisiana Louisiana State University Health Science Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting Baltimore, Maryland, United States, 21287 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Massachusetts Boston Medical Center Recruiting Boston, Massachusetts, United States, 02118 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Beth Israel Deaconess Medical Center Active, not recruiting Boston, Massachusetts, United States, 02215 United States, Missouri Siteman Cancer Center at Washington University Recruiting Saint Louis, Missouri, United States, 63110 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Washington University - Jewish Recruiting Saint Louis, Missouri, United States, 63110 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, New York Montefiore Medical Center-Einstein Campus Recruiting Bronx, New York, United States, 10461 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Pennsylvania Pennsylvania Oncology Hematology Associates Recruiting Philadelphia, Pennsylvania, United States, 19106 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Washington Virginia Mason Medical Center Recruiting Seattle, Washington, United States, 98101 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein Fred Hutchinson Cancer Research Center Recruiting Seattle, Washington, United States, 98109 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein France Centre Hospitalier Universitaire (CHU) de Toulouse Recruiting Cedex, France, 31059 Contact: Pierre Delobel 33-5-6177-7508 delobel.p@chu-toulouse.fr Principal Investigator: Pierre Delobel Hopital Antoine Beclere Recruiting Clamart, France, 92140 Contact: Francois Boue 33-1-4537-4409 francois.boue@abc.aphp.fr Principal Investigator: Francois Boue Henri Mondor University-Hospital Center Recruiting Creteil, France, 94000 Contact: Corinne Haioun 33-1-49-81-20-51 corinne.haioun@hmn.aphp.fr Principal Investigator: Corinne Haioun Hopital l'Archet-CHU de Nice Recruiting Nice, France, 06202 Contact: Nicolas Mounier 334-9203-5841 mounier.n@chu-nice.fr Principal Investigator: Nicolas Mounier Hopital Saint Louis Recruiting Paris, France, 75010 Contact: Eric Oksenhendler 33-1-4249-9811 eric.oksenhendler@sls.aphp.fr Principal Investigator: Eric Oksenhendler Hospital Saint-Antoine Recruiting Paris, France, 75012 Contact: Paul Coppo 33-1-4928-2616 paul.coppo@sat.aphp.fr Principal Investigator: Paul Coppo Centre Hospitalier Lyon-Sud Recruiting Pierre Benite, France, 69310 Contact: Gilles Salles 33-(0)-4-78-86-43-02 gilles.salles@chu-lyon.fr Principal Investigator: Gilles Salles Chu Purpan Recruiting Toulouse, France, 31059 Contact: Paul G. Rubinstein (312) 864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein 收起 <<
NCT02086604	Lymphoma, Large B-Cell, Diffus... 展开 >>e 收起 <<	Phase 1	Active, not recruiting	November 30, 2019	United States, Missouri ... 展开 >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, Ohio Ohio State University, James Cancer Hospital Columbus, Ohio, United States, 43210 收起 <<
NCT01578967	-		Active, not recruiting	-	-
NCT02505269	Hodgkin Lymphoma	Phase 2	Completed	-	United States, Massachusetts ... 展开 >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 收起 <<
NCT02689219	Germ Cell Tumors ... 展开 >> Testis Cancer Testicular Cancer Embryonal Carcinoma Nonseminomatous Germ Cell Tumor 收起 <<	Phase 2	Recruiting	December 31, 2019	United States, California ... 展开 >> USC/Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Charis Barg, RN 323-865-0845 charis.barg@med.usc.edu Principal Investigator: David Quinn, MD United States, Indiana Indiana University Health Hospital Recruiting Indianapolis, Indiana, United States, 46202 Contact: Yvonne LaFary, RN 317-278-5613 ylafary@iu.edu Principal Investigator: Costantine Albany, MD Indiana University Health Melvin and Bren Simon Cancer Center Recruiting Indianapolis, Indiana, United States, 46202 Contact: Yvonne LaFary, RN 317-278-5613 ylafary@iu.edu Principal Investigator: Costantine Albany, MD United States, New York Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Darren R. Feldman, MD 646-422-4491 feldman@mskcc.org Principal Investigator: Darren R. Feldman, MD United States, Utah Intermountain Precision Genomics Cancer Research Clinic Withdrawn Murray, Utah, United States, 84107 收起 <<
NCT03473691	Triple Negative Breast Cancer	Early Phase 1	Withdrawn(Pharmaceutical compa... 展开 >>ny decided to withdraw funding and not provide drug.) 收起 <<	May 1, 2018	-
NCT01902160	Recurrent Adult Hodgkin Lympho... 展开 >>ma 收起 <<	Phase 1	Completed	-	United States, New York ... 展开 >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 收起 <<
NCT01620229	Hematopoietic/Lymphoid Cancer	Phase 1 Phase 2	Withdrawn	-	United States, Washington ... 展开 >> Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Seattle, Washington, United States, 98109 收起 <<
NCT01703949	CD30-Positive Neoplastic Cells... 展开 >> Present Recurrent Hodgkin Lymphoma Recurrent Non-Hodgkin Lymphoma Refractory Hodgkin Lymphoma Refractory Non-Hodgkin Lymphoma 收起 <<	Phase 2	Recruiting	-	United States, Washington ... 展开 >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Ajay K. Gopal 206-606-2037 agopal@u.washington.edu Principal Investigator: Ajay K. Gopal 收起 <<
NCT02298257	HIV Infection ... 展开 >> HIV-associated Hodgkin Lymphoma Stage III Adult Hodgkin Lymphoma Stage IV Adult Hodgkin Lymphoma 收起 <<	Phase 2	Active, not recruiting	December 2019	France ... 展开 >> APHP - Hôpital Antoine Béclère Clamart, France, 92140 CHU de Nice Nice, France, 06202 APHP - Hôpital Saint Antoine Paris Cedex 12, France, 75571 Hopital St Louis Paris, France, 75475 Centre Hospitalier Lyon Sud Pierre Bénite, France, 69495 CHU de Toulouse Toulouse, France 收起 <<
NCT01026233	Disease, Hodgkin ... 展开 >> Lymphoma, Large-Cell, Anaplastic Lymphoma, Non-Hodgkin 收起 <<	Phase 1	Completed	-	United States, Alabama ... 展开 >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294-3300 United States, California City of Hope National Medical Center Duarte, California, United States, 91010 Stanford Cancer Center Stanford, California, United States, 94305 United States, Florida University of Miami Hospital and Clinics, Miller School of Medicine Miami, Florida, United States, 33136 United States, Illinois Cardinal Bernardin Cancer Center / Loyola University Medical Center Maywood, Illinois, United States, 60153 United States, New York New York University Cancer Institute New York, New York, United States, 10016 United States, Pennsylvania Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 United States, Texas Baylor University Medical Center Dallas, Texas, United States, 75246 Germany University Hospital of Cologne Koln, Germany, 50924 收起 <<
NCT02758717	Ann Arbor Stage IB Hodgkin Lym... 展开 >>phoma Ann Arbor Stage II Hodgkin Lymphoma Ann Arbor Stage IIA Hodgkin Lymphoma Ann Arbor Stage IIB Hodgkin Lymphoma Ann Arbor Stage III Hodgkin Lymphoma Ann Arbor Stage IIIA Hodgkin Lymphoma Ann Arbor Stage IIIB Hodgkin Lymphoma Ann Arbor Stage IV Hodgkin Lymphoma Ann Arbor Stage IVA Hodgkin Lymphoma Ann Arbor Stage IVB Hodgkin Lymphoma Classic Hodgkin Lymphoma 收起 <<	Phase 2	Recruiting	May 13, 2024	United States, California ... 展开 >> Stanford Cancer Institute Palo Alto Recruiting Palo Alto, California, United States, 94304 Contact: Ann Moffat 650-721-4096 amoffat@stanford.edu Principal Investigator: Ranjana H. Advani United States, District of Columbia MedStar Georgetown University Hospital Recruiting Washington, District of Columbia, United States, 20007 Contact: Pari Ramzi 202-784-0038 ramzip1@georgetown.edu Principal Investigator: Bruce D. Cheson United States, Illinois University of Chicago Comprehensive Cancer Center Withdrawn Chicago, Illinois, United States, 60637 United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Mayo Clinic Clinical Trials Office 507-538-7623 clinicaltrials@mayo.edu Principal Investigator: Stephen M. Ansell United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Kelly Hoye 314-362-4206 khoye@wustl.edu Principal Investigator: Nancy L. Bartlett United States, New Jersey Hackensack University Medical Center Recruiting Hackensack, New Jersey, United States, 07601 Contact: Kara M. Yannotti 551-996-5900 Kara.Yannotti@HackensackMeridian.org Principal Investigator: Tatyana A. Feldman United States, New York Laura and Isaac Perlmutter Cancer Center at NYU Langone Recruiting New York, New York, United States, 10016 Contact: Mohammad Maher Abdul-Hay 212-731-5670 Maher.Abdulhay@nyumc.org Principal Investigator: Catherine S. Diefenbach United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Rashmeet Reen 614-688-9283 rashmeet.reen@osumc.edu Principal Investigator: Kristie A. Blum United States, Texas M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Emily Wesson 713-794-5656 etwesson@mdanderson.org Principal Investigator: Michelle A. Fanale 收起 <<
NCT02616965	Cutaneous T-cell Lymphoma (CTC... 展开 >>L) 收起 <<	Phase 1	Recruiting	July 2021	United States, Pennsylvania ... 展开 >> Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111 Contact: Stefan K. Barta, MD 215-728-2674 Principal Investigator: Stefan K. Barta, MD 收起 <<
NCT03057795	Classical Hodgkin Lymphoma ... 展开 >> Hematopoietic Cell Transplantation Recipient Recurrent Hodgkin Lymphoma Refractory Hodgkin Lymphoma 收起 <<	Phase 2	Recruiting	October 2019	United States, California ... 展开 >> City of Hope Medical Center Recruiting Duarte, California, United States, 91010 Contact: Alex Herrera, MD 626-256-4673 aherrera@coh.org Principal Investigator: Alex Herrera United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Clinical Trials Referral Office https://www.mayo.edu/research/forms/cancer-clinical-trials 855-776-0015 Principal Investigator: Patrick B. Johnston, MD United States, New Jersey Hackensack University Medical Center Not yet recruiting Hackensack, New Jersey, United States, 07601 Contact: Alan P. Skarbnik 212-996-5900 Alan.Skarbnik@hackensackmeridian.org Principal Investigator: Alan P. Skarbnik United States, New York Memorial Sloan-Kettering Cancer Center Not yet recruiting New York, New York, United States, 10065 Contact: Gunjan L. Shah shahg@mskcc.org Principal Investigator: Gunjan L. Shah United States, Texas M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Yago L. Nieto 713-792-8750 ynieto@mdanderson.org Principal Investigator: Yago L. Nieto United States, Washington Fred Hutchinson Cancer Research Center Not yet recruiting Seattle, Washington, United States, 98109 Contact: Leona A. Holmberg 206-288-2035 lholmber@fredhutch.org Principal Investigator: Leona A. Holmberg 收起 <<
NCT02363283	Recurrent Uveal Melanoma ... 展开 >> Stage IV Uveal Melanoma AJCC v7 收起 <<	Phase 2	Completed	-	-
NCT03409432	Lymphomatoid Papulosis ... 展开 >> Primary Cutaneous Anaplastic Large Cell Lymphoma Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Recurrent T-Cell Non-Hodgkin Lymphoma Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Stage I Cutaneous T-Cell Non-Hodgkin Lymphoma Stage II Cutaneous T-Cell Non-Hodgkin Lymphoma Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma 收起 <<	Phase 2	Recruiting	April 30, 2020	United States, Ohio ... 展开 >> Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Basem M. William, MD 614-688-7942 basem.william@osumc.edu Principal Investigator: Basem M. William, MD 收起 <<
NCT01992653	Lymphoma, Non Hodgkin	Phase 1 Phase 2	Active, not recruiting	January 25, 2019	United States, Alabama ... 展开 >> The University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, Arizona Banner MD Anderson Cancer Center Gilbert, Arizona, United States, 85234 United States, Michigan Karmanos Cancer Institute Detroit, Michigan, United States, 48201 United States, Missouri Washington University; Pediatrics Saint Louis, Missouri, United States, 63110 United States, Oregon Northwest Cancer Specialists Portland, Oregon, United States, 97210 Oregon Health and Science University Portland, Oregon, United States, 97239 Willamette Valley Clinical Studies; Cancer Institute Springfield, Oregon, United States, 97477 United States, Texas Cancer Care Centers of South Texas San Antonio, Texas, United States, 78212 United States, Virginia Blue Ridge Cancer Care Roanoke, Virginia, United States, 24014 United States, Washington Northwest Medical Specialties, PLLC; Research Department Tacoma, Washington, United States, 98405 France Hopital Henri Mondor, Unite Hemopathies lymphoides Creteil, France, 94010 Hopital Claude Huriez - CHU Lille; Service des maladies du sang Lille, France, 59037 Hopital Haut-Leveque - Centre Francois Magendie; Service d'Hematologie Clinique Pessac, France, 33604 Centre Hospitalier Lyon Sud; Hematolgie Pierre Benite, France, 69495 Hopital Pontchaillou - CHU de Rennes Rennes, France, 35033 Centre Henri Becquerel; Hematologie Rouen, France, 76038 收起 <<
NCT02487979	Recurrent Osteosarcoma	Phase 2	Completed	-	-
NCT03373305	CD30-Positive Neoplastic Cells... 展开 >> Present Folliculotropic Mycosis Fungoides Recurrent Mycosis Fungoides Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Refractory Mycosis Fungoides Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Sezary Syndrome 收起 <<	Phase 1	Not yet recruiting	December 2020	United States, California ... 展开 >> City of Hope Medical Center Not yet recruiting Duarte, California, United States, 91010 Contact: Jasmine Zain, MD Principal Investigator: Jasmine Zain, MD 收起 <<
NCT02729961	Anaplastic Large Cell Lymphoma... 展开 >>, ALK-Positive CD30-Positive Neoplastic Cells Present Systemic Anaplastic Large Cell Lymphoma 收起 <<	Phase 1 Phase 2	Recruiting	July 1, 2023	United States, Washington ... 展开 >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Andrei R. Shustov 206-606-6744 ashustov@u.washington.edu Principal Investigator: Andrei R. Shustov 收起 <<
NCT01874054	Hodgkin Disease	Phase 1 Phase 2	Completed	-	United States, Alabama ... 展开 >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Pacific Hematology Oncology Associates San Francisco, California, United States, 94115 Stanford Cancer Center Stanford, California, United States, 94305 Oncology Institute of Hope & Innovation, The Whittier, California, United States, 90603 United States, Colorado Colorado Blood Cancer Institute Denver, Colorado, United States, 80218 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, Minnesota Mayo Clinic Minnesota Rochester, Minnesota, United States, 55905 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-7680 United States, New York Columbia University Medical Center New York, New York, United States, 10022 United States, Ohio Jewish Hospital, The Cincinnati, Ohio, United States, 45236 Case Western Reserve University / University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 United States, South Carolina Saint Francis Hospital / Bon Secours Greenville, South Carolina, United States, 29601 United States, Texas Charles A. Sammons Cancer Center / Baylor University Medical Center Dallas, Texas, United States, 75246 收起 <<
NCT03496779	Refractory Peripheral T-Cell L... 展开 >>ymphoma Relapsed Peripheral T-Cell Lymphoma 收起 <<	Phase 2	Recruiting	October 2022	Belgium ... 展开 >> ZNA Stuivenberg Recruiting Antwerpen, Belgium, 2060 Contact: Ka Lung WU, MD A. Z. Sint-Jan Recruiting Bruges, Belgium, 8000 Contact: Sylvia SNAUWAERT, MD Clinique Universitaire Saint LUC Recruiting Brussels, Belgium, 1200 Contact: Eric VAN DEN NESTE, Pr Institut Jules Bordet Recruiting Brussels, Belgium Contact: Marie MAEREVOET, MD ULB Hôpital Erasme Recruiting Brussels, Belgium Contact: Virginie DE WILDE, MD UZ Gent Recruiting Gent, Belgium, 9000 Contact: Fritz OFFNER, MD CHU de Liege Recruiting Liege, Belgium, 4000 Contact: Christophe BONNET, MD CHU UCL Namur Recruiting Yvoir, Belgium Contact: Marc ANDRE, MD France IHBN - CHU Cote de Nacre Recruiting Amiens, France, 80054 Contact: Ghandi DAMAJ, MD CHU d'Amiens Recruiting Amiens, France Contact: Caroline DELETTE, MD CHU Angers Recruiting Angers, France, 49033 Contact: Marie-Pierre MOLES-MOREAU, MD CH d'Avignon - Hôpital Henri Dufaut Recruiting Avignon, France, 84000 Contact: Hacene ZERAZHI, MD CH Côte Basque Recruiting Bayonne, France, 64100 Contact: Anne BANOS, MD CHU de Besançon - Hôpital Jean Minjoz Recruiting Besançon, France, 25030 Contact: Adrien CHAUCHET, MD CH Chambéry Recruiting Chambery, France, 73011 Contact: Maya Hacini, MD CHU d'Estaing Recruiting Clermont-Ferrand, France, 63000 Contact: Sebastien BAILLY, MD APHP - Hopital Henri Mondor Recruiting Creteil, France, 94010 Contact: Jehan DUPUIS, MD CHU de Dijon - Hôpital le Bocage Recruiting Dijon, France, 21000 Contact: Olivier CASASNOVAS, MD CHU Grenoble Recruiting Grenoble, France, 38043 Contact: Remy GRESSIN, MD CH de Versailles - Hopital André Mignot Recruiting Le Chesnay, France, 78157 Contact: Hassan Farhat, MD CH du Mans Recruiting Le Mans, France, 72000 Contact: Kamel LARIBI, Dr CHRU de Lille - Hôpital Claude Huriez Recruiting Lille, France Contact: Franck MORSCHHAUSER, Pr CHU de Limoges Recruiting Limoges, France Contact: Arnaud JACCARD, MD Centre Leon Berard Recruiting Lyon Cedex 8, France, 69373 Contact: Emmanuelle NICOLAS-VIRELIZIER, MD Institut Paoli Calmettes Withdrawn Marseille, France, 13000 Centre Hospitalier Annecy Genevois Recruiting Metz-Tessy, France, 74374 Contact: Nicolas DAGUINDAU, MD CH Saint-Eloi Recruiting Montpellier, France, 34295 Contact: Guillaume CARTRON, MD 04 67 33 83 62 Principal Investigator: Guillaume CARTRON, MD CH de Mulhouse Sud Alsace Recruiting Mulhouse, France, 68070 Contact: Bernard DRENOU, MD CHU Nancy - Brabois Recruiting Nancy, France, 54511 Contact: Pierre Feugier, MD CHU de Nantes - Hôtel Dieu Recruiting Nantes, France, 44093 Contact: Steven LE GOUILL, Pr APHP - Hôpital Saint Louis Recruiting Paris Cedex 10, France, 75475 Contact: Catherine Thieblemont, MD APHP - Hôpital Necker Recruiting Paris, France, 75015 Contact: Richard Delarue, MD Centre François Magendie - Hôpital du Haut Lévêque Recruiting Pessac, France, 33604 Contact: Kamal BOUABDALLAH, MD Centre Hospitalier Lyon Sud Recruiting Pierre Bénite, France, 69495 Contact: Emmanuel BACHY, MD CHU de Poitiers - Hôpital de la Milétrie Recruiting Poitiers, France, 86021 Contact: Vincent DELWAIL, MD CHU De Rennes Recruiting Rennes, France, 35033 Contact: Thierry LAMY DE LA CHAPELLE, MD Centre Henri BECQUEREL Recruiting Rouen, France, 76038 Contact: Hervé TILLY, Pr CHU de Toulouse Recruiting Toulouse, France, 31059 Contact: Loïc Ysebaert, MD CHRU de Tours Recruiting Tours, France, 37044 Contact: Emmanuel Gyan, MD CH de Valenciennes Recruiting Valenciennes, France, 59322 Contact: Sabine TRICOT, MD 收起 <<
NCT02096042	Leukemia	Phase 1 Phase 2	Terminated(Slow accrual.)	-	United States, Texas ... 展开 >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT02169505	Lymphoma	Phase 2	Terminated(Slow Accrual)	-	United States, Texas ... 展开 >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT03657043	Ovarian Cancer ... 展开 >> Fallopian Tube Cancer Peritoneal Cancer 收起 <<	Phase 2	Not yet recruiting	September 2021	-
NCT02096042	-		Terminated(Slow accrual.)	-	-
NCT01950364	Hodgkin Lymphoma ... 展开 >> Anaplastic Large-cell Lymphoma 收起 <<	Phase 1	Completed	-	Belgium ... 展开 >> Brussels, Belgium Gent, Belgium Lithuania Vilnius, Lithuania Spain Barcelona, Spain Madrid, Spain Salamanca, Spain 收起 <<
NCT01874054	-		Completed	-	-
NCT02988843	Germ Cell Tumor	Phase 2	Suspended(Funding Unavailable)	February 2021	United States, Minnesota ... 展开 >> University of Minnesota Minneapolis, Minnesota, United States, 55455 收起 <<
NCT01900496	Lymphoma	Phase 1	Terminated(Low accrual)	-	United States, Maryland ... 展开 >> The Sidney Kimmel Comprehensive Canceer Center Baltimore, Maryland, United States, 21287 收起 <<
NCT01950364	-		Completed	-	-
NCT01830777	Acute Myelogenous Leukemia	Phase 1	Active, not recruiting	December 2019	United States, Massachusetts ... 展开 >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 收起 <<
NCT02487979	-		Completed	-	-
NCT01461538	Acute Lymphoid Leukemia ... 展开 >> Acute Myeloid Leukemia Anemia, Refractory, With Excess of Blasts Solid Tumors 收起 <<	Phase 2	Completed	-	-
NCT01461538	-		Completed	-	-
NCT02552121	Ovary Cancer ... 展开 >>Cervix Cancer Endometrium Cancer Bladder Cancer Prostate Cancer (CRPC) Esophagus Cancer Lung Cancer (NSCLC) 收起 <<	Phase 1 Phase 2	Completed	-	United States, Texas ... 展开 >> MD Anderson Cancer Center Houston, Texas, United States, 77030 Belgium Institut Jules Bordet Bruxelles, Brussels, Belgium, 1000 Universitaire Ziekenhuizen Leuven Leuven, Flemish Brabant, Belgium, 3000 Grand Hôpital de Charleroi Charleroi, Hainaut, Belgium, 6000 CHU de Liège Liege, Liège, Belgium, 4000 CHU UCL Namur - site Godinne Yvoir, Namur, Belgium, 5530 Cliniques Universitaires Saint-Luc Brussels, Belgium, 1200 CHU UCL Namur - Sainte Elisabeth Namur, Belgium, 5000 Denmark Rigshospitalet, Copenhagen University Hospital Copenhagen, Denmark, DK-2100 Hungary Petz Aladár Megyei Oktató Kórház Gyor, Gyor-Moson-Sopron, Hungary, 9023 Debreceni Egyetem Klinikai Központ Debrecen, Hajdu-Bihar, Hungary, 4032 Semmelweis Egyetem Onkológiai Központ Budapest, Hungary, 1083 United Kingdom University College London Hospitals NHS Foundation Trust London, England, United Kingdom, NW1 2PG Sarah Cannon Cancer Center London, England, United Kingdom, W1G 6AD The Christie NHS Foundation Trust Manchester, England, United Kingdom, M20 4BX The Royal Marsden NHS Foundation Trust Sueery, United Kingdom, SM2 5PT 收起 <<
NCT02572167	Hodgkin Lymphoma	Phase 1 Phase 2	Active, not recruiting	October 2020	United States, California ... 展开 >> City of Hope National Medical Center Duarte, California, United States, 91010-3000 Stanford Cancer Center Stanford, California, United States, 94305 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, Michigan Karmanos Cancer Institute / Wayne State University Detroit, Michigan, United States, 48201 United States, Minnesota Mayo Clinic Minnesota Rochester, Minnesota, United States, 55905 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-7680 United States, New Jersey Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, New York Memorial Sloan Kettering Cancer Center - Commack Commack, New York, United States, 11725 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10021 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio James Cancer Hospital / Ohio State University Columbus, Ohio, United States, 43210 United States, Texas Charles A. Sammons Cancer Center / Baylor University Medical Center Dallas, Texas, United States, 75246 收起 <<
NCT03326258	Advanced Malignant Solid Neopl... 展开 >>asm Estrogen Receptor Negative GPNMB Positive HER2/Neu Negative Metastatic Malignant Solid Neoplasm Metastatic Melanoma Progesterone Receptor Negative Stage III Breast Cancer AJCC v7 Stage III Cutaneous Melanoma AJCC v7 Stage III Uveal Melanoma AJCC v7 Stage IIIA Cutaneous Melanoma AJCC v7 Stage IIIB Cutaneous Melanoma AJCC v7 Stage IIIC Cutaneous Melanoma AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Stage IV Cutaneous Melanoma AJCC v6 and v7 Stage IV Uveal Melanoma AJCC v7 Triple-Negative Breast Carcinoma Unresectable Solid Neoplasm 收起 <<	Phase 1 Phase 2	Withdrawn(The study itself was... 展开 >> Disapproved on 04/20/2018 and will not be moving forward.) 收起 <<	-	-
NCT02302339	Melanoma	Phase 2	Terminated(Development of glem... 展开 >>batumumab vedotin was discontinued) 收起 <<	-	United States, California ... 展开 >> The Angeles Clinic and Research Institute Los Angeles, California, United States, 90025 Northern California Melanoma Center/St. Mary's Medical Center San Francisco, California, United States, 94117 United States, Florida Florida Cancer Specialists Fort Myers, Florida, United States, 33916 Mount Sinai Comprehensive Cancer Center Miami Beach, Florida, United States, 33140 Florida Cancer Specialists West Palm Beach, Florida, United States, 33407 United States, Georgia Northside Hospital Cancer Institute Atlanta, Georgia, United States, 30341 United States, Illinois University of Chicago Medicine Chicago, Illinois, United States, 60637 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, New York New York University School of Medicine New York, New York, United States, 10016 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Tennessee Tennessee Oncology Nashville, Tennessee, United States, 37203 Vanderbilt-Ingram Cancer Center Nashville, Tennessee, United States, 37232 United States, Texas Baylor Research Institute-Sammons Cancer Center Dallas, Texas, United States, 75246 收起 <<
NCT03438396	Cervical Cancer	Phase 2	Recruiting	April 2023	-
NCT02581631	Non-Hodgkin's Disease	Phase 1 Phase 2	Recruiting	February 13, 2020	-
NCT01657331	Hodgkin Lymphoma ... 展开 >> Anaplastic Large Cell Lymphoma 收起 <<	Phase 1 Phase 2	Active, not recruiting	April 2019	United States, New York ... 展开 >> Columbia University Medical Center New York, New York, United States, 10019 Canada, British Columbia British Columbia Cancer Agency Vancouver, British Columbia, Canada, V5z 4E6 Canada, Ontario Princess Margaret Hospital Toronto, Ontario, Canada 收起 <<
NCT02533570	Systemic Lupus Erythematosus	Phase 2	Terminated(Sponsor decision ba... 展开 >>sed on portfolio prioritization) 收起 <<	-	United States, Alabama ... 展开 >> University of Alabama at Birmingham - (UAB) Birmingham, Alabama, United States, 35294 United States, California TriWest Research Associates, LLC El Cajon, California, United States, 92020-4124 Advanced Medical Research, LLC La Palma, California, United States, 90623 United States, Colorado University of Colorado Aurora, Colorado, United States, 80045 United States, Florida Clinical Research of West Florida - Corporate Clearwater, Florida, United States, 33765 Lakes Research, LLC Miami Lakes, Florida, United States, 33014 Arthritis Associates Orlando, Florida, United States, 32804 McIlwain Medical Group Tampa, Florida, United States, 33613 United States, Michigan Henry Ford Health System Detroit, Michigan, United States, 48202 United States, Missouri Clayton Medical Associates, P.C. Saint Louis, Missouri, United States, 63117 United States, New York Weill Cornell Physicians at Brooklyn Heights Brooklyn, New York, United States, 11201 United States, North Carolina DJL Clinical Research, PLLC Charlotte, North Carolina, United States, 28210 United States, Oklahoma Arthritis & Rheumatology Center of Oklahoma Oklahoma City, Oklahoma, United States, 73103 United States, Tennessee Ramesh C Gupta MD Memphis, Tennessee, United States, 38119 United States, Texas Tekton Research, Inc. Austin, Texas, United States, 78745 Accurate Clinical Research Houston, Texas, United States, 77034 United States, Virginia Arthritis Clinic of Northern Virginia, PC Arlington, Virginia, United States, 22205-3606 收起 <<
NCT02254239	Recurrent Hodgkin Lymphoma ... 展开 >> Refractory Hodgkin Lymphoma 收起 <<	Phase 1	Suspended(Per study design)	September 30, 2020	United States, Minnesota ... 展开 >> Mayo Clinic Rochester, Minnesota, United States, 55905 收起 <<
NCT02533570	-		Terminated(Sponsor decision ba... 展开 >>sed on portfolio prioritization) 收起 <<	-	-
NCT01805037	Adult Grade III Lymphomatoid G... 展开 >>ranulomatosis Adult Nasal Type Extranodal NK/T-cell Lymphoma Anaplastic Large Cell Lymphoma Angioimmunoblastic T-cell Lymphoma Contiguous Stage II Adult Burkitt Lymphoma Contiguous Stage II Adult Diffuse Large Cell Lymphoma Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma Contiguous Stage II Adult Lymphoblastic Lymphoma Contiguous Stage II Grade 1 Follicular Lymphoma Contiguous Stage II Grade 2 Follicular Lymphoma Contiguous Stage II Grade 3 Follicular Lymphoma Contiguous Stage II Mantle Cell Lymphoma Contiguous Stage II Marginal Zone Lymphoma Contiguous Stage II Small Lymphocytic Lymphoma Cutaneous B-cell Non-Hodgkin Lymphoma Epstein-Barr Virus Infection Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Hepatosplenic T-cell Lymphoma Intraocular Lymphoma Nodal Marginal Zone B-cell Lymphoma Noncontiguous Stage II Adult Burkitt Lymphoma Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma Noncontiguous Stage II Adult Lymphoblastic Lymphoma Noncontiguous Stage II Grade 1 Follicular Lymphoma Noncontiguous Stage II Grade 2 Follicular Lymphoma Noncontiguous Stage II Grade 3 Follicular Lymphoma Noncontiguous Stage II Mantle Cell Lymphoma Noncontiguous Stage II Marginal Zone Lymphoma Noncontiguous Stage II Small Lymphocytic Lymphoma Noncutaneous Extranodal Lymphoma Peripheral T-cell Lymphoma Post-transplant Lymphoproliferative Disorder Progressive Hairy Cell Leukemia, Initial Treatment Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Grade III Lymphomatoid Granulomatosis Recurrent Adult Hodgkin Lymphoma Recurrent Adult Immunoblastic Large Cell Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Adult T-cell Leukemia/Lymphoma Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Recurrent Small Lymphocytic Lymphoma Refractory Hairy Cell Leukemia Small Intestine Lymphoma Splenic Marginal Zone Lymphoma Stage I Adult Burkitt Lymphoma Stage I Adult Diffuse Large Cell Lymphoma Stage I Adult Diffuse Mixed Cell Lymphoma Stage I Adult Diffuse Small Cleaved Cell Lymphoma Stage I Adult Hodgkin Lymphoma Stage I Adult Immunoblastic Large Cell Lymphoma Stage I Adult Lymphoblastic Lymphoma Stage I Adult T-cell Leukemia/Lymphoma Stage I Cutaneous T-cell Non-Hodgkin Lymphoma Stage I Grade 1 Follicular Lymphoma Stage I Grade 2 Follicular Lymphoma Stage I Grade 3 Follicular Lymphoma Stage I Mantle Cell Lymphoma Stage I Marginal Zone Lymphoma Stage I Small Lymphocytic Lymphoma Stage IA Mycosis Fungoides/Sezary Syndrome Stage IB Mycosis Fungoides/Sezary Syndrome Stage II Adult Hodgkin Lymphoma Stage II Adult T-cell Leukemia/Lymphoma Stage II Cutaneous T-cell Non-Hodgkin Lymphoma Stage IIA Mycosis Fungoides/Sezary Syndrome Stage IIB Mycosis Fungoides/Sezary Syndrome Stage III Adult Burkitt Lymphoma Stage III Adult Diffuse Large Cell Lymphoma Stage III Adult Diffuse Mixed Cell Lymphoma Stage III Adult Diffuse Small Cleaved Cell Lymphoma Stage III Adult Hodgkin Lymphoma Stage III Adult Immunoblastic Large Cell Lymphoma Stage III Adult Lymphoblastic Lymphoma Stage III Adult T-cell Leukemia/Lymphoma Stage III Cutaneous T-cell Non-Hodgkin Lymphoma Stage III Grade 1 Follicular Lymphoma Stage III Grade 2 Follicular Lymphoma Stage III Grade 3 Follicular Lymphoma Stage III Mantle Cell Lymphoma Stage III Marginal Zone Lymphoma Stage III Small Lymphocytic Lymphoma Stage IIIA Mycosis Fungoides/Sezary Syndrome Stage IIIB Mycosis Fungoides/Sezary Syndrome Stage IV Adult Burkitt Lymphoma Stage IV Adult Diffuse Large Cell Lymphoma Stage IV Adult Diffuse Mixed Cell Lymphoma Stage IV Adult Diffuse Small Cleaved Cell Lymphoma Stage IV Adult Hodgkin Lymphoma Stage IV Adult Immunoblastic Large Cell Lymphoma Stage IV Adult Lymphoblastic Lymphoma Stage IV Adult T-cell Leukemia/Lymphoma Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma Stage IV Grade 1 Follicular Lymphoma Stage IV Grade 2 Follicular Lymphoma Stage IV Grade 3 Follicular Lymphoma Stage IV Mantle Cell Lymphoma Stage IV Marginal Zone Lymphoma Stage IV Small Lymphocytic Lymphoma Stage IVA Mycosis Fungoides/Sezary Syndrome Stage IVB Mycosis Fungoides/Sezary Syndrome T-cell Large Granular Lymphocyte Leukemia Testicular Lymphoma Untreated Hairy Cell Leukemia Waldenström Macroglobulinemia 收起 <<	Phase 1 Phase 2	Unknown	-	United States, Illinois ... 展开 >> Northwestern University Recruiting Chicago, Illinois, United States, 60611 Contact: Adam M. Petrich, MD 312-695-6180 apetrich@nmff.org Principal Investigator: Adam M. Petrich, MD Sub-Investigator: Leo Gordon, MD Sub-Investigator: Jane Winter, MD Sub-Investigator: Shuo Ma, MD, PhD Sub-Investigator: Steven Rosen, MD Sub-Investigator: Amy Chadburn, MD University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Chadi Nabhan, MD 773-702-9574 Principal Investigator: Chadi Nabhan, MD United States, Massachusetts Tufts University School of Medicine Recruiting Boston, Massachusetts, United States, 02111 Contact: Andrew M. Evens, MD 617-636-8077 Principal Investigator: Andrew M. Evens, MD 收起 <<
NCT03485209	Colorectal Neoplasms ... 展开 >> Carcinoma, Non-Small-Cell Lung Exocrine Pancreatic Cancer Carcinoma, Squamous Cell of Head and Neck 收起 <<	Phase 2	Recruiting	April 2021	United States, California ... 展开 >> University of California Davis Recruiting Davis, California, United States, 95616 Contact: Michelle Cregan 916-734-8512 mpcregan@ucdavis.edu Principal Investigator: May Cho Stanford Cancer Center / Blood and Marrow Transplant Program Recruiting Stanford, California, United States, 94305 Contact: Ann Moffat 669-233-2816 amoffat@stanford.edu Principal Investigator: Omid Tehrani United States, Connecticut Yale Cancer Center Recruiting New Haven, Connecticut, United States, 06520 Contact: Erica Carbone 203-737-4645 erica.carbone@yale.edu Principal Investigator: Jill Lacy, MD United States, Florida Shands Cancer Center / University of Florida Recruiting Gainesville, Florida, United States, 32610 Contact: Ashton Monismith 352-265-0680 amonismith@ufl.edu Principal Investigator: Thomas George, MD United States, Georgia Winship Cancer Institute / Emory University School of Medicine Recruiting Atlanta, Georgia, United States, 30322 Contact: Monique Guyinn 404-778-1900 monique.guyinn@emory.edu Principal Investigator: Conor Steuer United States, Illinois Ingalls Cancer Care / Ingalls Memorial Hospital Recruiting Harvey, Illinois, United States, 60426 Contact: Margaret Marriott 703-339-4800 mmarriott@ingalls.org Principal Investigator: Kimberly Kruczek, MD United States, Kansas University of Kansas Cancer Center Recruiting Westwood, Kansas, United States, 66205 Contact: Michelle Cairns 913-945-7547 mcairns3@kumc.edu Principal Investigator: Anwaar Saeed United States, Kentucky Norton Cancer Institute Recruiting Louisville, Kentucky, United States, 40202 Contact: Catherine Conway 502-629-4267 catherine.conway@nortonhealthcare.org Principal Investigator: John Hamm, MD United States, Massachusetts Dana Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Ketki Bhushan 617-632-4270 Ketki_Bhushan@DFCI.HARVARD.EDU Principal Investigator: Geoffrey Shapiro United States, Minnesota HealthPartners Institute Recruiting Saint Louis Park, Minnesota, United States, 55426 Contact: Alissa Gavenda 952-993-6071 Alissa.Gavenda@ParkNicollet.com Principal Investigator: Daniel Anderson, MD United States, Oregon Oregon Health and Science University Recruiting Portland, Oregon, United States, 97239-3098 Contact: Zack Godwin 503-494-1617 godwinz@ohsu.edu Principal Investigator: Matthew Taylor, MD United States, Rhode Island Rhode Island Hospital Recruiting Providence, Rhode Island, United States, 02903 Contact: John Vatkevich 401-444-6217 John.vatkevich@lifespan.org Principal Investigator: Howard Safran United States, Texas MD Anderson Cancer Center / University of Texas Recruiting Houston, Texas, United States, 77030-4095 Contact: Meiyue Hong 713-745-4367 mghong@mdanderson.org Principal Investigator: David Hong Joe Arrington Cancer Research and Treatment Center Recruiting Lubbock, Texas, United States, 79410 Contact: Mary Jane Flores 806-725-7993 maryjane.Flores@stjoe.org Principal Investigator: Isaac Tafur, MD 收起 <<
NCT03474133	Hodgkin's Lymphoma	Phase 2	Not yet recruiting	December 2, 2023	-
NCT02979522	Hodgkin Disease	Phase 1 Phase 2	Recruiting	October 29, 2021	United States, Arkansas ... 展开 >> Arkansas Children's Hospital Recruiting Little Rock, Arkansas, United States, 72202 United States, Colorado Children's Hospital Colorado Recruiting Aurora, Colorado, United States, 80045 United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 United States, Ohio Cincinnati Childrens Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229-3039 Brazil Hospital Sao Rafael S/A Recruiting Salvador, Bahia, Brazil, 41253-190 INCA - Instituto Nacional de Cancer Recruiting Rio de Janeiro, Rio Do Janeiro, Brazil, 20230-230 Hospital de Clinicas de Porto Alegre Recruiting Porto Alegre, Rio Grande Do Sul, Brazil, 90035-903 Hospital de Cancer de Barretos - Fundacao Pio XII Recruiting Barretos, Sao Paulo, Brazil, 14784-400 Jardim das Americas Recruiting Parana, Brazil, 81520-060 GRAACC - Grupo de Apoio ao Adolescente e a Crianca com Cancer Recruiting Sao Paulo, Brazil, 04023-062 ICr - Instituto da Crianca - HCFMUSP Recruiting Sao Paulo, Brazil, 05403-000 Hospital Santa Marcelina Recruiting Sao Paulo, Brazil, 08270-070 Hong Kong The Chinese University of Hong Kong Recruiting Shatin, Hong Kong, 00000 Italy Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi Recruiting Bologna, Italy, 40138 Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer Recruiting Firenze, Italy, 50139 Fondazione IRCCS Policlinico San Matteo Recruiting Pavia, Italy, 27100 Ospedale Pediatrico Bambino Gesu,UOC Onco-ematologia Recruiting Roma, Italy, 165 Azienda Ospedaliera Citta della Salute e della Scienza di Torino Recruiting Torino, Italy, 10126 Japan NHO Nagoya Medical Center Recruiting Nagoya-shi, Aichi-Ken, Japan, 460-0001 Kyushu University Hospital Recruiting Fukuoka-shi, Fukuoka-Ken, Japan, 812-8582 Hokuyukai Sapporo Hokuyu Hospital Recruiting Sapporo-shi, Hokkaido, Japan, 003-0006 St. Marianna University School of Medicine Hospital Recruiting Kawasaki-shi, Kanagawa-Ken, Japan, 216-8511 Singapore National University Cancer Institute Singapore Recruiting Singapore, Singapore, 119228 Taiwan Taichung Veterans General Hospital Recruiting Taichung, Taiwan, 40705 National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 收起 <<
NCT01578499	Primary Cutaneous Anaplastic L... 展开 >>arge Cell Lymphoma Mycosis Fungoides Cutaneous T-Cell Lymphoma 收起 <<	Phase 3	Completed	-	-
NCT01780662	Recurrent Adult Hodgkin Lympho... 展开 >>ma Recurrent Childhood Hodgkin Lymphoma Refractory Childhood Hodgkin Lymphoma 收起 <<	Phase 1 Phase 2	Active, not recruiting	-	-
NCT01578499	-		Completed	-	-
NCT03222492	Diffuse Cutaneous Systemic Scl... 展开 >>erosis Scleroderma dcSSc 收起 <<	Phase 1 Phase 2	Recruiting	September 2020	United States, California ... 展开 >> UCLA Medical Center: Division of Rheumatology Recruiting Los Angeles, California, United States, 90095 Contact: Nashla Barroso 310-825-9682 nbarroso@mednet.ucla.edu Principal Investigator: Suzanne Kafaja, MD United States, District of Columbia Georgetown University Medical Center: Division of Rheumatology Recruiting Washington, District of Columbia, United States, 20057 Contact: Sabrina Elliott 202-444-6210 sabrina.elliott@georgetown.edu Principal Investigator: Virginia Steen, MD United States, Massachusetts Boston University School of Medicine: Rheumatology Section, Scleroderma Clinical Centers Recruiting Boston, Massachusetts, United States, 02118 Contact: Connor Buchholz 617-358-6797 connorbu@bu.edu Principal Investigator: Robert Simms, MD United States, Michigan University of Michigan Health System: Department of Internal Medicine, Division of Rheumatology Recruiting Ann Arbor, Michigan, United States, 48109 Contact: Monica Sanborn 734-232-2090 monan@med.umich.edu Principal Investigator: Vivek Nagaraja, MD United States, Minnesota Minnesota University of Minnesota, Division of Rheumatology Not yet recruiting Minneapolis, Minnesota, United States, 55455 Principal Investigator: Jerry A. Molitor, MD United States, New York Hospital for Special Surgery, New York: Division of Rheumatology Recruiting New York, New York, United States, 10021 Contact: Jesse Ojeda 212-774-7620 ojeda@hss.edu Principal Investigator: Jessica Gordon, MD United States, North Carolina Duke University Medical Center: Division of Rheumatology and Immunology Recruiting Durham, North Carolina, United States, 27710 Contact: Karissa Grier 919-684-6150 karissa.grier@duke.edu Principal Investigator: Ankoor Shah, MD United States, Pennsylvania University of Pittsburgh Medical Center: Division of Rheumatology and Clinical Recruiting Pittsburgh, Pennsylvania, United States, 15217 Contact: Dana Ivanco 412-648-7040 des2@pitt.edu Principal Investigator: Robert Lafyatis,, MD United States, South Carolina Medical University of South Carolina: Division of Rheumatology & Immunology Recruiting Charleston, South Carolina, United States, 29425 Contact: Nathan Wilson 843-792-8272 wilsonn@musc.edu Principal Investigator: Richard Silver, MD United States, Texas University of Texas Houston Medical School: Division of Rheumatology and Clinical Immunogenetics Recruiting Houston, Texas, United States, 77030 Contact: Pat Gonzales 713-500-7118 patricia.gonzales@uth.tmc.edu Principal Investigator: Maureen Mayes, MD, MPH Canada, Ontario Toronto Mount Sinai Hospital Not yet recruiting Toronto, Ontario, Canada, ON M5G 1X5 Contact: Judith Guthrie judith.guthrie@sinaihealthsystem.ca Principal Investigator: Sindu R. Johnson, MD,PhD,FRCPC 收起 <<
NCT02429375	Hodgkin Lymphoma	Phase 1 Phase 2	Active, not recruiting	April 2019	United States, New York ... 展开 >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 收起 <<
NCT02244021	Relapsed/Refractory Hodgkin's ... 展开 >>Lymphoma 收起 <<	Phase 2	Completed	-	Italy ... 展开 >> Istituto di Ematologia "L. & A. Seragnoli" , Policlinico S. Orsola Malpighi Bologna, Italy Ematologia, IRCCS AOU San Martino-IST Genova, Italy Ematologia Ospedale Vito Fazzi Lecce, Italy Ematologia e Unità BMT IRCCS Istituto Nazionale dei Tumori Milano, Italy Università degli Studi di Modena e Reggio Emilia, D.A.I di Medicina diagnostica clinica e sanità pubblica, AOU Policlinico Modena, Italy Dipartimento di Oncologia Medica ed Ematologia, Istituto Humanitas Rozzano, Italy SC Ematologia - Azienda Ospedaliera AO Città della Salute e della Scienza Torino, Italy 收起 <<
NCT03219333	Carcinoma, Transitional Cell ... 展开 >> Urinary Bladder Neoplasms Urologic Neoplasms Renal Pelvis Neoplasms Urothelial Cancer Ureteral Neoplasms Urethral Neoplasms 收起 <<	Phase 2	Recruiting	May 2025	-
NCT01700751	Leukemia, Acute Myeloid ... 展开 >> Leukemia, Lymphoblastic,Acute Myelodysplastic Syndromes 收起 <<	Phase 1	Active, not recruiting	January 31, 2020	United States, Missouri ... 展开 >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 收起 <<
NCT01396070	Non-Hodgkin Lymphoma (NHL) ... 展开 >> Cutaneous Lymphoma Cutaneous T-cell Lymphoma (CTCL) Mycosis Fungoides Sezary Syndrome 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Stanford University School of Medicine Stanford, California, United States, 94305 收起 <<
NCT02462538	ALK+ Anaplastic Large Cell Lym... 展开 >>phoma 收起 <<	Phase 1 Phase 2	Recruiting	June 2021	Austria ... 展开 >> Universitätsklinik für Innere Medizin V Recruiting Innsbruck, Austria, A-6020 Contact: Angelina Rauth 0043512504 ext 23382 studienambulanz.haematologie@uki.at Principal Investigator: Wolfgang Willenbacher, Dr AKH Linz, Innere Medizin 3, Zentrum f. Haematologie u. med. Onkologie Recruiting Linz, Austria, A-4021 Contact: Bettina Pfleger +43 7327806 ext 6207 bettina.pfleger@akh.linz.at Contact: Elisabeth Morbitzer +43 7327806 ext 6204 elisabeth.morbitzer@akh.linz.at Principal Investigator: Michael A. Fridrik, Univ.Doz.Dr Universitätsklinik der PMU, Universitätsklinik für Innere Medizin III Recruiting Salzburg, Austria, 5020 Contact: Michaela Schachner, Mag. +43 662 4482 ext 2847 m.schachner@salk.at Principal Investigator: Richard Greil, Univ.Prof.Dr Universitätsklinik f. Innere Medizin I, AKH Wien, Klinische Abteilung für Hämatologie und Hämostaseologie Recruiting Wien, Austria, 1090 Contact: Natascha Vydra + 43 1 40400 ext 44100 natascha.vydra@meduniwien.ac.at Principal Investigator: Ulrich Jäger, Univ.Prof.Dr 收起 <<
NCT01616680	Graft Versus Host Disease	Phase 2	Withdrawn	-	United States, Washington ... 展开 >> Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Seattle, Washington, United States, 98109 收起 <<
NCT03539536	Non-small Cell Lung Cancer	Phase 2	Recruiting	December 10, 2021	-
NCT02497131	Lymphatic Diseases	Phase 2	Recruiting	December 2021	Italy ... 展开 >> Ematologia "L. & A. Seragnoli" - Policlinico S. Orsola Malpighi Recruiting Bologna, Italy, 40138 Contact: Vittorio Stefoni, MD +39.0516363680 vittorio.stefoni2@unibo.it A.O.Spedali civili di Brescia Not yet recruiting Brescia, Italy Principal Investigator: Giuseppe Rossi, MD Ematologia e Trapianto IRCCS, Istituto Nazionale dei Tumori Recruiting Milano, Italy Principal Investigator: Paolo Corradini, MD SC Ematologia - Città della Salute e della Scienza Recruiting Torino, Italy, 10126 Principal Investigator: Umberto Vitolo, MD A.O. Universitaria S. Maria Della Misericordia Di Udine Recruiting Udine, Italy, 33100 Principal Investigator: Stefano Volpetti, MD 收起 <<
NCT03187210	Lymphoma	Phase 1 Phase 2	Recruiting	June 2022	Switzerland ... 展开 >> Department for Medical Oncology University Hospital/Inselspital Recruiting Berne, Switzerland, 3010 Principal Investigator: Thomas Pabst, Prof Dr med 收起 <<
NCT02423291	Primary Mediastinal Large B Ce... 展开 >>ll Lymphoma 收起 <<	Phase 2	Completed	-	Italy ... 展开 >> S.C. Ematologia A.O. SS. Antonio e Biagio e C. Arrigo Alessandria, AL, Italy, 15121 Unità funzionale di Ematologia A.O.U. Careggi Firenze, FI, Italy, 50134 Dip. Oncologia, Ematologia e Patologie dell'apparato respiratorio A.O.U. Policlinico di Modena Modena, MO, Italy, 41100 Divisione di Ematologia Azienda Ospedaliera "Bianchi Melacrino Morelli" Reggio Calabria, RC, Italy, 89125 S. C. Ematologia IRCCS Azienda Ospedaliera Arcispedale "S.Maria Nuova" Reggio Emilia, RE, Italy, 4210 S.C.D.O. Ematologia 2 A.O. Città della Salute e della Scienza Torino, TO, Italy, 1012 Istituto di Ematologia L. & A. Seragnoli Bologna, Italy, 40138 Ematologia Ospedale Businco Cagliari, Italy, 09121 Dipartimento di Biotecnologie Cellulari ed Ematologia Università "La Sapienza" Roma, Italy, 0016 收起 <<
NCT02423291	-		Completed	-	-
NCT01596218	Graft vs. Host Disease	Phase 1	Completed	-	United States, Massachusetts ... 展开 >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States United States, Ohio Ohio State University Columbus, Ohio, United States 收起 <<
NCT01396070	-		Completed	-	-
NCT03245736	Ovary Cancer ... 展开 >>Cervix Cancer Endometrium Cancer Bladder Cancer Prostate Cancer Esophagus Cancer Lung Cancer, Nonsmall Cell Squamous Cell Carcinoma of the Head and Neck 收起 <<	Phase 2	Recruiting	January 1, 2022	United States, Florida ... 展开 >> Brian Slomovitz Recruiting Miami, Florida, United States, 33136 Contact: Brian Slomovitz, Dr United Kingdom Johann de Bono Recruiting Chelsea, United Kingdom, SM2 5PT Contact: Johann de Bono, Professor Beatson Cancer Centre Recruiting Glasgow, United Kingdom Principal Investigator: Robert Jones, Dr Fiona Thistlethwaite Recruiting Manchester, United Kingdom, M20 4BX Contact: Fiona Thistlethwaite, Dr 收起 <<
NCT02227433	Hodgkin Lymphoma	Phase 2	Active, not recruiting	April 2019	Italy ... 展开 >> Irccs Centro Di Riferimento Oncologico Di Aviano (Pn) Aviano, Italia, Italy, 33081 Policlinico S.Orsola Malpighi Bologna, Italy Irccs Istituto Nazionale Per Lo Studio E La Cura Dei Tumori Fondazione Giovanni Pascale Di Napoli Napoli, Italy Università La Sapienza Rome, Italy, 00161 收起 <<
NCT01421667	Lymphoma, B-Cell ... 展开 >> Lymphoma, Large B-Cell, Diffuse Lymphoma, Non-Hodgkin Lymphoma, T-Cell 收起 <<	Phase 2	Completed	-	-
NCT01851200	Germ Cell Cancer	Phase 2	Completed	-	Italy ... 展开 >> Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Mi, Italy, 20133 收起 <<
NCT01807598	Aggressive Systemic Mastocytos... 展开 >>is Mast Cell Leukemia Systemic Mastocytosis 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Stanford University, School of Medicine Stanford, California, United States, 94305 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT01421667	-		Completed	-	-
NCT01508312	Hodgkin's Lymphoma	Phase 2	Active, not recruiting	September 2019	United States, New York ... 展开 >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 收起 <<
NCT01671813	Lymphoma	Not Applicable	Withdrawn(Terminated by pharma... 展开 >>ceutical sponsor - no accrual) 收起 <<	-	-
NCT02939014	Hodgkin Disease ... 展开 >> Lymphoma, Large-Cell, Anaplastic 收起 <<	Phase 2	Active, not recruiting	December 1, 2019	China, Beijing ... 展开 >> Beijing, Beijing, China China, Guangdong Guangzhou, Guangdong, China China, Jiangsu Nanjing, Jiangsu, China China, Jilin Changchun, Jilin, China China, Shanghai Shanghai, Shanghai, China China, Tianjin Tianjin, Tianjin, China China, Zhejiang Hangzhou, Zhejiang, China 收起 <<
NCT02588651	T-cell Lymphoma ... 展开 >> Angioimmunoblastic T-cell Lymphoma Hepato-splenic T-cell Lymphoma Adult T-cell Leukemia/Lymphoma Enteropathy Associated T-cell Lymphoma NK T-cell Lymphoma Transformed Mycosis Fungoides 收起 <<	Phase 2	Recruiting	December 2022	United States, Michigan ... 展开 >> University of Michigan Recruiting Ann Arbor, Michigan, United States, 48109-5413 Contact: Ryan Wilcox, MD rywilcox@umich.edu Principal Investigator: Ryan Wilcox, MD Wayne State University, Karmanos Cancer Institute Recruiting Detroit, Michigan, United States, 48201 Contact: Radhakrishnan Ramchandren, MD 313-576-8739 ramchanr@karmanos.org Principal Investigator: Radhakrishnan Ramchandren, MD United States, New Jersey Hackensack University Medical Center Recruiting Hackensack, New Jersey, United States, 07601 Contact: Tatyana Feldman, MD 551-996-5900 Tatyana.Feldman@HackensackMeridian.org Principal Investigator: Tatyana Feldman, MD United States, Ohio University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center Recruiting Cleveland, Ohio, United States, 44106 Contact: Paolo Caimi, MD 216-844-0139 Paolo.Caimi@uhhospitals.org Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center Recruiting Cleveland, Ohio, United States, 44195 Contact: Deepa Jagadeesh, MD, MPH 216-444-0857 jagaded@ccf.org 收起 <<
NCT02280785	Non-Hodgkin Lymphoma	Phase 2	Completed	-	Korea, Republic of ... 展开 >> National Cancer Center Goyang-si, Gyeonggi-do, Korea, Republic of, 410-769 Yonsei Severance Hospital Seoul, Korea, Republic of, 120-752 Asan Medical Center Seoul, Korea, Republic of, 138-736 Korean Cancer Center Hospital Seoul, Korea, Republic of, 139-706 收起 <<
NCT01841021	Peripheral T-Cell Lymphoma	Not Applicable	Terminated(Slow accrual, loss ... 展开 >>of sponsor support) 收起 <<	-	United States, Florida ... 展开 >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 收起 <<
NCT01909934	Anaplastic Large-cell Lymphoma	Phase 4	Recruiting	April 23, 2020	-
NCT01393717	Recurrent Hodgkin Lymphoma ... 展开 >> Refractory Hodgkin Lymphoma 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> City of Hope Medical Center Duarte, California, United States, 91010 United States, New York Weill Medical College, Cornell University New York, New York, United States, 10065 收起 <<
NCT03587844	Mycosis Fungoides ... 展开 >> Lymphomatoid Papulosis 收起 <<	Phase 2	Recruiting	July 2020	United States, California ... 展开 >> Stanford University Medical Center Not yet recruiting Stanford, California, United States, 94305-5408 Contact: Youn Kim, MD 650-498-6000 United States, New Jersey Memorial Sloan Kettering Basking Ridge Recruiting Basking Ridge, New Jersey, United States, 07920 Contact: Alison Moskowitz, MD 212-639-4839 Memorial Sloan Kettering Monmouth Recruiting Middletown, New Jersey, United States, 07748 Contact: Alison Moskowitz, MD 212-639-4839 United States, New York Memorial Sloan Kettering Commack Recruiting Commack, New York, United States, 11725 Contact: Alison Moskowitz, MD 212-639-4839 Memorial Sloan Kettering Westchester Recruiting Harrison, New York, United States, 10604 Contact: Alison Moskowitz, MD 212-639-4839 Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Alison Moskowitz, MD 212-639-4839 Contact: Steven Horwitz, MD 212-639-3045 Principal Investigator: Alison Moskowitz, MD Memorial Sloan Kettering Rockville Centre Recruiting Rockville Centre, New York, United States, 11570 Contact: Alison Moskowtiz, MD 212-639-4839 收起 <<
NCT01393717	-		Completed	-	-
NCT01841021	-		Terminated(Slow accrual, loss ... 展开 >>of sponsor support) 收起 <<	-	-
NCT02780011	CD30-positive Lymphoma ... 展开 >> CD30-positive Solid Tumor 收起 <<	Phase 1	Withdrawn(lack of funding)	September 2018	United States, Texas ... 展开 >> Houston Methodist Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT03205891	Malignant Neoplasms Stated as ... 展开 >>Primary Lymphoid Haematopoietic Classical Hodgkin Lymphoma Anaplastic Large Cell Lymphoma CD30+ Peripheral T-cell Lymphoma 收起 <<	Phase 1	Withdrawn(Change in treatment ... 展开 >>priorities for these disease types as well as staffing concerns.) 收起 <<	March 2021	-
NCT01492088	-		Completed	-	-
NCT01990534	-		Active, not recruiting	-	-
NCT01990534	Hodgkin Lymphoma	Phase 4	Active, not recruiting	March 2020	Czech Republic ... 展开 >> Praha, Prague, Czech Republic Brno, Czech Republic Germany Heidelberg, Baden Wuerttemberg, Germany Koeln, Germany Malaysia Georgetown, Penang, Malaysia Ampang, Selangor, Malaysia Kuala Lumpur, Malaysia Poland Gdansk, Poland Krakow, Poland Warszawa, Poland Spain Pamplona, Navarra, Spain Madrid, Spain Thailand Bangkoknoi, Bangkok, Thailand Patumwan, Bangkok, Thailand Ratchathewi, Bangkok, Thailand Turkey Izmir, Bornova, Turkey Ankara, Turkey Izmir, Turkey 收起 <<
NCT03007030	Lung Diseases Due to External ... 展开 >>Agents Mesothelioma 收起 <<	Phase 2	Recruiting	April 2022	United States, Texas ... 展开 >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact astsao@mdanderson.org 收起 <<
NCT02567851	Hodgkin Disease	Phase 2	Completed	-	United Kingdom ... 展开 >> Queen Elizabeth Hospital Birmingham, United Kingdom University Hospital of Wales Cardiff, United Kingdom Beatson West of Scotland Cancer Center Glasgow, United Kingdom St James University Hospital Leeds, United Kingdom University Hospital Leicester, United Kingdom Royal Liverpool Hospital Liverpool, United Kingdom Guys Hospital London, United Kingdom The Christie Hospital Manchester, United Kingdom, M20 4BX The Freeman Hospital Newcastle, United Kingdom Norfolk and Norwich Hospital Norwich, United Kingdom The Churchill Hospital Oxford, United Kingdom Southampton General Hospital Southampton, United Kingdom 收起 <<
NCT02713828	Squamous Cell Carcinoma of the... 展开 >> Lung 收起 <<	Phase 1 Phase 2	Terminated(Company discontinue... 展开 >>d further development of study drug for this indication) 收起 <<	-	United States, Florida ... 展开 >> University of Miami Hospital Miami, Florida, United States, 33136 United States, Georgia Emory University Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Louisiana Ochsner Medical Center New Orleans, Louisiana, United States, 70121 United States, Nebraska Missouri Valley Cancer Consortium Omaha, Nebraska, United States, 68106 United States, New Jersey Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08903 United States, New York Stony Brook University Stony Brook, New York, United States, 11794-9446 United States, Pennsylvania Penn State Hershey Cancer Institute Hershey, Pennsylvania, United States, 17033 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75390 United States, West Virginia West Virginia University Morgantown, West Virginia, United States, 26506 United States, Wisconsin Gundersen Health System La Crosse, Wisconsin, United States, 54601 收起 <<
NCT01492088	Relapsed or Refractory Hodgkin... 展开 >> Lymphoma Relapsed or Refractory Anaplastic Large-cell Lymphoma 收起 <<	Phase 1 Phase 2	Completed	-	United States, Colorado ... 展开 >> Aurora, Colorado, United States United States, Missouri Kansas City, Missouri, United States United States, New York New York, New York, United States United States, Texas Houston, Texas, United States France Bordeaux Cedex, France Lyon, France Paris Cedex 12, France Germany Berlin, Germany Frankfurt, Germany Giessen, Germany Halle, Germany Munster, Germany Italy Padova, Italy Roma, Italy Mexico Mexico Df, Mexico Netherlands Rotterdam, Netherlands Spain Barcelona, Spain United Kingdom London, United Kingdom 收起 <<
NCT02388490	Relapsed or Refractory EBV-and... 展开 >> CD30-positive Lymphomas 收起 <<	Phase 2	Active, not recruiting	September 2018	Korea, Republic of ... 展开 >> Seoul National University Bundang Hospital Seongnam, Korea, Republic of Seoul National Unversity Hospital Seoul, Korea, Republic of SMG-SNU Boramae Medical Center Seoul, Korea, Republic of 收起 <<
NCT03070990	Metastatic Urothelial Cancer	Phase 1	Active, not recruiting	March 2019	Japan ... 展开 >> Site JP00003 Tsukuba, Ibaraki, Japan Site JP00005 Sendai, Miyagi, Japan Site JP00008 Suita, Osaka, Japan Site JP00004 Chuo, Tokyo, Japan Site JP00007 Koto, Tokyo, Japan Site JP00006 Fukuoka, Japan Site JP00001 Niigata, Japan Site JP00002 Okayama, Japan 收起 <<
NCT03302728	Lymphoma, T-Cell, Cutaneous ... 展开 >> Lymphoma, T-Cell, Peripheral Hodgkin Lymphoma 收起 <<	Phase 1	Not yet recruiting	August 15, 2021	Australia, Victoria ... 展开 >> Peter MacCallum Cancer Centre Not yet recruiting Melbourne, Victoria, Australia, 3000 Contact: Maria Farrell, Ms 收起 <<
NCT01940796	Graft-vs-Host Disease ... 展开 >> GVHD 收起 <<	Phase 1	Terminated(Toxicity)	-	United States, Massachusetts ... 展开 >> Massachusetts General Hospital Boston, Massachusetts, United States, 02215 收起 <<
NCT02164006	Hodgkin's Lymphoma	Phase 1	Active, not recruiting	February 2019	United States, California ... 展开 >> TG Therapeutics Investigational Trial Site Duarte, California, United States, 91010 TG Therapeutics Investigational Trial Site San Diego, California, United States, 92093 United States, Florida TG Therapeutics Investigational Trial Site Sarasota, Florida, United States, 34232 United States, Michigan TG Therapeutics Investigational Trial Site Detroit, Michigan, United States, 48201 收起 <<

描述	Monomethyl auristatin E (MMAE) produced under Good Manufacturing Practice (GMP) guidelines is a version of MMAE that inhibits tubulin polymerization^[1].
体内研究	The combination of Monomethyl auristatin E (MMAE) with ionizing radiation (IR) leads to delayed tumor growth, whereas the use of tumor-targeting ACPP-cRGD-MMAE alongside IR results in a more pronounced and prolonged regression of tumors in xenograft models^[2].
体外研究	Within CD30+ cancer cells, Monomethyl auristatin E (MMAE) is effectively liberated from SGN-35 and can kill adjacent non-targeted cells due to its ability to permeate cell membranes^[1]. MMAE enhances the sensitivity of colorectal and pancreatic cancer cells to ionizing radiation (IR) in a manner that is both schedule and dose-dependent, which is associated with mitotic arrest. This increased radiosensitivity results in reduced clonogenic survival and a higher incidence of DNA double-strand breaks in cells subjected to irradiation^[2].
作用机制	MMAE binds to tubulin and interferes with microtubule formation.^[4]

Dose	Cynomolgus monkey: 0.3 mg/kg - 3 mg/kg^[5] (i.v.) Rat: 0.03 mg/kg - 0.2 mg/kg^[6] (i.v.) Mice: 0.3 mg/kg^[7] (i.v.)
Administration	i.v.

CAS号	474645-27-7
分子式	C₃₉H₆₇N₅O₇
分子量	717.98
SMILES Code	O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](NC)C(C)C)=O)=O)=O)OC)=O
MDL No.	MFCD22124498

别名	MMAE; Vedotin; Brentuximab vedotin; SGD-1010
运输	蓝冰

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