Idebenone | CV-2619;Mnesis;Catena, Raxone, Sovrima | Iron death Inhibitor | ROS

首页 / / / / Idebenone/艾地苯醌

Idebenone/艾地苯醌 {[allProObj[0].p_purity_real_show]}

货号：A249566 同义名： CV-2619; Mnesis

Idebenone是辅酶Q10（CoQ10）的合成类似物，能保护线粒体膜免受脂质过氧化，同时作为神经保护剂使用。

Idebenone/艾地苯醌化学结构
CAS号：58186-27-9

Idebenone/艾地苯醌 3D分子结构
CAS号：58186-27-9

规格	价格	会员价	库存	数量
{[ item.pr_size ]}	{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}	{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}	{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]}	{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]}	现货	1周咨询	- +

购物车0 收藏询单

sales@ambeed.cn tech@ambeed.cn 400-920-2911 产品手册产品订购技术咨询
快速发货顺丰冷链运输，1-2 天到达

品质保证

技术支持

免费溶解

Idebenone/艾地苯醌纯度/质量文件产品仅供科研

货号：A249566 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Science, 2025, 387(6729): eadp5637. Ambeed. [ A875019 ]; • Nat. Electron., 2025, 8, 66-74. Ambeed. [ A100095 ]; • Adv. Mater., 2025, 2416621. Ambeed. [ A255324 , A420052 ]; • Adv. Mater., 2025, 2410493. Ambeed. [ A838608 ]; • Adv. Mater., 2025, 2420319. Ambeed. [ A106129 ]; 更多 >

Idebenone/艾地苯醌生物活性

描述	Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which targets mitochondria, preserves mitochondrial function, and confers cytoprotection. In this way, idebenone has neuroprotective effects and has applications in Friedreich ataxia.

Idebenone/艾地苯醌临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03014856	-		Completed	-	-
NCT00224640	Friedreich Ataxia	Phase 1 Phase 2	Completed	-	France ... 展开 >> Necker Hospital Paris, France, 75015 收起 <<
NCT03014908	-		Completed	-	Belgium ... 展开 >> Hasselt University Hasselt, Limburg, Belgium, 3500 收起 <<

Idebenone/艾地苯醌参考文献

[1]Rego AC, Santos MS, Oliveira CR. Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress. Free Radic Biol Med. 1999 Jun;26(11-12):1405-17.

[2]Yamada K, Tanaka T, et al. Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivo. Eur J Neurosci. 1999 Jan;11(1):83-90.

Idebenone/艾地苯醌实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.95mL

0.59mL

0.30mL

14.77mL

2.95mL

1.48mL

29.55mL

5.91mL

2.95mL

Idebenone/艾地苯醌技术信息

CAS号	58186-27-9
分子式	C₁₉H₃₀O₅
分子量	338.44
SMILES Code	O=C1C(CCCCCCCCCCO)=C(C)C(C(OC)=C1OC)=O
MDL No.	MFCD00274552

别名	CV-2619; Mnesis; Catena, Raxone, Sovrima
运输	蓝冰
InChI Key	JGPMMRGNQUBGND-UHFFFAOYSA-N
Pubchem ID	3686

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,2-8°C

溶解方案

细胞实验：

DMSO: 105 mg/mL(310.25 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验：请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议现用现配，当天使用；以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

方案二

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03014856	-		Completed	-	-
NCT00224640	Friedreich Ataxia	Phase 1 Phase 2	Completed	-	France ... 展开 >> Necker Hospital Paris, France, 75015 收起 <<
NCT03014908	-		Completed	-	Belgium ... 展开 >> Hasselt University Hasselt, Limburg, Belgium, 3500 收起 <<
NCT01421381	-		Completed	-	Canada, Quebec ... 展开 >> Hôpital Notre-Dame (CHUM) Montreal,, Quebec, Canada, H2L 4M1 Germany Friedrich Baur Institut Neurologische Klinik und Poliklinik München, Germany, D-80336 United Kingdom Biomedical Research Centre, The Medical School Newcastle upon Tyne, United Kingdom, NE2 4HH 收起 <<
NCT02774005	Leber's Hereditary Optic Neuro... 展开 >>pathy (LHON) 收起 <<	Phase 4	Recruiting	February 2021	-
NCT01495715	Leber's Hereditary Optic Neuro... 展开 >>pathy 收起 <<	Phase 3	Withdrawn	-	-
NCT00015808	Friedreich Ataxia	Phase 1	Completed	-	United States, Maryland ... 展开 >> National Institute of Neurological Disorders and Stroke (NINDS) Bethesda, Maryland, United States, 20892 收起 <<
NCT02887443	Drug-Drug Interaction	Phase 1	Completed	-	France ... 展开 >> Eurofins Optimed Gières, France, 38610 收起 <<
NCT00078481	Friedreich Ataxia	Phase 1	Completed	-	United States, Maryland ... 展开 >> National Institute of Neurological Disorders and Stroke (NINDS) Bethesda, Maryland, United States, 20892 收起 <<
NCT00654784	Duchenne Muscular Dystrophy (D... 展开 >>MD) 收起 <<	Phase 2	Completed	-	Belgium ... 展开 >> Children's Hospital, University Hospital Leuven, Belgium 收起 <<
NCT02771379	-		Recruiting	February 2021	Austria ... 展开 >> Universitaetsklinikum Graz Recruiting Graz, Austria, 8036 Principal Investigator: Mona Schneider, MD Medical University of Vienna Recruiting Vienna, Austria Principal Investigator: Berthold Pemp, MD France CHU de Nîmes - Hôpital Carémeau Recruiting Nîmes, Gard, France, 30029 Principal Investigator: Luc Jeanjean, MD CHU Angers - Hôpital Hôtel Dieu Recruiting Angers, Maine Et Loire, France, 49033 Principal Investigator: Christophe Verny, MD Hopital Roger Salengro - CHU Lille Recruiting Lille, Nord, France, 59037 Principal Investigator: Sabine Defoort Delemmes, MD Hôpital Européen Georges Pompidou Recruiting Paris, Paris Cedex 15, France, 75908 Principal Investigator: Christophe Orssaud, MD CHU Amiens - Centre Saint Victor Recruiting Amiens, Somme, France, 80054 Principal Investigator: Solange Milazzo, MD Hopital Neurologique Pierre Wertheimer Recruiting Lyon Cedex, France, 69677 Principal Investigator: Damien Biotti, MD Hospices Civils de Lyon Recruiting Lyon, France, 69002 Principal Investigator: Caroline Tilikete, MD Centre Hospitalier National d'Ophtalmologie (CHNO) des Quinze-Vingts Recruiting Paris, France, 75012 Principal Investigator: Catherine Vignal, MD Fondation Ophtalmologique Adolphe de Rothschild Recruiting Paris, France, 75019 Principal Investigator: Rabih Hage, MD Germany Julius Maximilians University Recruiting Wuerzburg, Baden Wuerttemberg, Germany, 97070 Principal Investigator: Thomas Ach, MD Charite - Campus Virchow-Klinikum Recruiting Berlin, Germany, 13353 Principal Investigator: Uwe Pleyer, MD Universitaetsklinikum Essen Recruiting Essen, Germany Principal Investigator: Michael Oeverhaus, MD Universitaetsklinikum Freiburg Recruiting Freiburg, Germany Principal Investigator: Wolf Lagreze Universitaetsklinikum Hamburg-Eppendorf Recruiting Hamburg, Germany, 20246 Principal Investigator: Martin Spitzer, MD Universitaetsklinikum Heidelberg Recruiting Heidelberg, Germany Principal Investigator: Klaus Rohrschneider, MD Friedrich-Baur-Institut Recruiting Munich, Germany Principal Investigator: Thomas Klopstock Universitaetsklinikum Muenster Recruiting Munster, Germany Principal Investigator: Nicole Eter, MD Universitaetsklinikum Neubrandenburg Recruiting Neubrandenburg, Germany Principal Investigator: Herbert Jaegle, MD Universitaetsklinikum Regensburg Recruiting Regensburg, Germany Principal Investigator: Helmut Hoeh, MD Greece Athens Ophthalmological Center Recruiting Athens, Greece, 11528 Principal Investigator: Agathi Kouri, MD Italy Università di Bologna-Clinica Neurologica-Dipartimento di Scienze Neurologiche Not yet recruiting Bologna, Italy, 40123 Principal Investigator: Valerio Carelli, MD Ospedale San Raffaele Recruiting Milano, Italy, 20132 Principal Investigator: Francesco Maria Bandello, MD Azienda Ospedaliera S. Camillo Forlanini Not yet recruiting Rome, Italy, 00152 Principal Investigator: Anna De Negri, MD Netherlands Universitair Medisch Centrum Groningen Recruiting Groningen, Netherlands, 9713 GZ Principal Investigator: Jan-Willem Pott, MD Maastricht University Medical Center Not yet recruiting Maastricht, Netherlands, 6211 LK Principal Investigator: Noël Bauer, MD 收起 <<
NCT01854359	Multiple Sclerosis ... 展开 >> Primary Progressive Multiple Sclerosis 收起 <<	Phase 1 Phase 2	Active, not recruiting	August 1, 2019	United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT00537680	Friedreich's Ataxia	Phase 3	Completed	-	United States, California ... 展开 >> David Geffen School of Medicine, UCLA Los Angeles, California, United States, 90095-1769 United States, Pennsylvania The Children's Hopsital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 收起 <<
NCT00654784	-		Completed	-	-
NCT00950248	Primary Progressive Multiple S... 展开 >>clerosis 收起 <<	Phase 1 Phase 2	Completed	-	United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT00537680	-		Completed	-	-
NCT00229632	Friedreich Ataxia	Phase 2	Completed	-	United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT00747487	Leber's Hereditary Optic Neuro... 展开 >>pathy 收起 <<	Phase 2	Completed	-	Canada, Quebec ... 展开 >> Unité de recherche clinique Ophtalmologie- Hopital Notre-Dame Montreal, Quebec, Canada, H2L 4M1 Germany Klinikum der Universität München - Grosshadern, Neurologische Klinik und Poliklinik Munich, Germany, 81377 United Kingdom Clinical Research Facility, 4th Floor Leazes Wing, Royal Victoria Infirmary Newcastle Upon Tyne, United Kingdom, NE1 4LP 收起 <<
NCT02814019	Duchenne Muscular Dystrophy (D... 展开 >>MD) 收起 <<	Phase 3	Recruiting	August 2019	-
NCT00905268	-		Completed	-	-
NCT00697073	Friedreich's Ataxia	Phase 3	Completed	-	United States, California ... 展开 >> David Geffen School of Medicine, UCLA Los Angeles, California, United States, 90095-1769 United States, Pennsylvania The Children's Hopsital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 收起 <<
NCT00697073	-		Completed	-	-
NCT01027884	Muscular Dystrophy, Duchenne ... 展开 >> Ambulatory Care 收起 <<	Phase 3	Completed	-	-
NCT01027884	-		Completed	-	-
NCT00905268	Friedreich's Ataxia	Phase 3	Completed	-	Austria ... 展开 >> Universitätsklinik Innsbruck Innsbruck, Austria, 6020 Belgium Hôpital Erasme - Université Libre de Bruxelles Bruxelles, Belgium, 1070 France Hôpital de la Salpêtrière - INSERM U679, Neurologie et Thérapeutique expérimentale Paris, France, 75651 Germany HELIOS Klinikum BerlinBuch Berlin, Germany, 13125 Neurologische Universitätsklinik und Poliklinik- Universitätsklinikum Bonn Bonn, Germany, 53105 Klinik II, Neuropädiatrie u.Muskelerkrankungen- Universitätsklinik Freiburg Freiburg, Germany, 79106 Zentrum für Neurologische Medizin Göttingen, Germany, 37073 UKE Hamburg Neuropädiatrie-Zentum für Frauen, Kinder und Jugendmedizin Hamburg, Germany, 20246 Neurologische Klinik- klinikum Grosshadern München, Germany, 81377 Neurologische Universitätsklinik und Poliklinik Tübingen, Germany, 72076 Netherlands University Medical Center Groningen Groningen, Netherlands, 9700 RB United Kingdom National Hospital for Neurology & Neurosurgery London, United Kingdom, WC1N 3BG University of Newcastle upon Tyne -Mitochondrial Research Group Newcastle, United Kingdom, NE2 4HH 收起 <<
NCT00993967	Freidreich's Ataxia	Phase 3	Completed	-	Austria ... 展开 >> Universitätsklinik Innsbruck Innsbruck, Austria Belgium Hôpital Erasme - Univeristé Libre de Bruxelles Bruxelles, Belgium, 1070 France Hôpital de la Salpétrière - INSERM U679, Neurologie et Thérapeutique expérimentale Paris, France, 75651 Germany HELIOS Klinikum Berlin Berlin, Germany, 13125 Neurologische Universitätsklinik und Ploklinik - Universitätsklimikum Bonn Bonn, Germany, 53105 Klinik II, Neuropädiatrie und Muskelerkrankungen - Universitätsklinik Freiburg Freiburg, Germany, 79106 Zentrum für Neurologische Medizin Göttingen, Germany, 37073 UKE Hamburg Neuropädiatrie - Zentrum für Frauen, Kinder und Jugendmedizin Hamburg, Germany, 20246 Neurologische Klinik - Klinikum Grosshadern München, Germany, 81377 Neurologische Universitätsklinik und Poliklinik Tübingen, Germany, 72076 Netherlands University medical Center Groningen Groningen, Netherlands, 9700 RB 收起 <<
NCT00758225	Duchenne Muscular Dystrophy	Phase 2	Completed	-	Belgium ... 展开 >> University Hospitals Leuven Leuven, Belgium, 3000 收起 <<
NCT00887562	-		Completed	-	-
NCT00993967	-		Completed	-	-
NCT03727295	Oxidative Stress is an Importa... 展开 >>nt Cause of Parkinson's Disease 收起 <<	Phase 4	Not yet recruiting	May 30, 2021	-
NCT01303406	Friedreich's Ataxia	Phase 3	Completed	-	Austria ... 展开 >> Innsbruck, Austria Germany Bonn, Germany München, Germany Tübingen, Germany Netherlands Groningen, Netherlands United Kingdom The National Hospital, University College London London, United Kingdom, WC 1N 3BG 收起 <<
NCT03433807	-		-	-	United States, Arizona ... 展开 >> Phoenix Children's Hospital Phoenix, Arizona, United States, 85016 Contact: Saunder Bernes, MD United States, Iowa University of Iowa Iowa City, Iowa, United States, 52242 Contact: Kathy Mathews, MD United States, Maryland Kennedy Krieger Baltimore, Maryland, United States, 21287 Contact: Kathryn Wagner, MD, PhD 收起 <<
NCT00887562	MELAS Syndrome	Phase 2	Completed	-	United States, New York ... 展开 >> Columbia University Medical Center New York, New York, United States, 10032 收起 <<
NCT03603288	Duchenne Muscular Dystrophy	Phase 3	Recruiting	January 2022	United States, Minnesota ... 展开 >> Gillette Children's Specialty Healthcare Recruiting Saint Paul, Minnesota, United States, 55101 Contact: Randel Richardson, MD Belgium University Hospital Leuven Recruiting Leuven, Belgium, 3000 Contact: Gunnar Buyse, MD Principal Investigator: Gunnar Buyse, MD CHR Citadelle Recruiting Liège, Belgium, 4000 Principal Investigator: Laurent Servais, MD Italy Fondazione IRCCS Eugenio Medea Recruiting Bosisio Parini, Italy, 23842 Contact: Maria Grazia Nadia D'Angelo, MD Principal Investigator: Maria Grazia Nadia D'Angelo, MD Switzerland Center for neuromuscular disorders, Universitäts-Kinderspital beider Basel (UKBB) Recruiting Basel, Switzerland, 4301 Principal Investigator: Andrea Klein, MD United Kingdom Robert Jones and Agnes Hunt Orthopaedic Hospital Recruiting Oswestry, United Kingdom, SY10 7AG Contact: Tracey Willis, MD Principal Investigator: Tracey Willis, MD 收起 <<
NCT01303406	-		Completed	-	-

Idebenone/艾地苯醌 {[allProObj[0].p_purity_real_show]}

Idebenone/艾地苯醌纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Idebenone/艾地苯醌质控信息

Idebenone/艾地苯醌生物活性

Idebenone/艾地苯醌临床研究

Idebenone/艾地苯醌参考文献

Idebenone/艾地苯醌实验方案

Idebenone/艾地苯醌技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

Idebenone/艾地苯醌 {[allProObj[0].p_purity_real_show]}

Idebenone/艾地苯醌 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Idebenone/艾地苯醌 质控信息

Idebenone/艾地苯醌 生物活性

Idebenone/艾地苯醌 临床研究

Idebenone/艾地苯醌 参考文献

Idebenone/艾地苯醌 实验方案

Idebenone/艾地苯醌 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

请登录您的专属账户

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

Idebenone/艾地苯醌纯度/质量文件产品仅供科研

Idebenone/艾地苯醌质控信息

Idebenone/艾地苯醌生物活性

Idebenone/艾地苯醌临床研究

Idebenone/艾地苯醌参考文献

Idebenone/艾地苯醌实验方案

Idebenone/艾地苯醌技术信息