货号:A2900876
同义名:
重组人UBE2M蛋白(E.coli, tag free)
/ Recombinant Human UBE2M
Recombinant Human UBE2M由大肠杆菌表达系统生产,目标基因编码Met1-Lys183。
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描述 | 产品名称:Recombinant Human UBE2M理论分子量:20.9 KDa蛋白种属:Human表达系统:E.coli蛋白表达区间:Met1-Lys183标签:Tag free剂型:液体纯度:≥95% as determined by reducing SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. UBE2M accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. It involved in cell proliferation and is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. |
CAS号 | N/A |
分子量 | 20.9 KDa |
SMILES Code | NONE |
别名 | 重组人UBE2M蛋白(E.coli, tag free) ;Recombinant Human UBE2M |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |