货号:A2900857
同义名:
重组人STAT6蛋白(E.coli, C-6His)
/ Recombinant Human STAT6 (C-6His); Signal Transducer and Activator of Transcription 6
Recombinant Human STAT6 (C-6His)由大肠杆菌表达系统生产,目标基因编码Ser627-Ser837,并在C末端带有6His标签。
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描述 | Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. STAT6 has been shown to interact with EP300, CREB-binding protein, NFKB1, Nuclear receptor coactivator 1, IRF4 and SND1. |
蛋白种属 | Human |
表达系统 | E.coli |
标签 | C-6His |
蛋白表达区间 | Ser627-Ser837 |
蛋白编号 | P42226 |
内毒素 | < 1 EU/µg as determined by LAL test. |
剂型 | 干粉 |
剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
CAS号 | N/A |
分子量 | 23.9 KDa |
SMILES Code | NONE |
别名 | 重组人STAT6蛋白(E.coli, C-6His) ;Recombinant Human STAT6 (C-6His); Signal Transducer and Activator of Transcription 6; IL-4 Stat; STAT6 |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |