Human STAT6 (C-6His)

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Chemical Structure| N/A 同义名 : 重组人STAT6蛋白(E.coli, C-6His) ;Recombinant Human STAT6 (C-6His); Signal Transducer and Activator of Transcription 6; IL-4 Stat; STAT6
CAS号 : N/A
货号 : A2900857
分子式 : -
纯度 : 85% determined by reducing SDS-PAGE.
分子量 : 23.9 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. STAT6 has been shown to interact with EP300, CREB-binding protein, NFKB1, Nuclear receptor coactivator 1, IRF4 and SND1.