货号:A2900908
同义名:
重组人PFKFB3蛋白(E.coli, N-6His)
/ Recombinant Human PFKFB3 (N-6His)
Recombinant Human PFKFB3 (N-6His)由大肠杆菌表达系统生产,目标基因编码Met1-His520,并在N末端带有6His标签。
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描述 | 产品名称:Recombinant Human PFKFB3 (N-6His)理论分子量:61.8 KDa蛋白种属:Human表达系统:E.coli蛋白表达区间:Met1-His520标签:N-6His剂型:液体纯度:≥95% as determined by reducing SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis. Highly phosphorylated PFKFB3 protein was found in human tumor cells, vascular endothelial cells, and smooth muscle cells. Because of its proto-oncogenic character, the PFK-2/FBPase-2 of the PFKFB3 gene is assumed to play a critical role in tumorigenesis. PFKFB3 also plays a crucial role in the progression of cancerous cells by enabling their glycolytic pathways even under severe hypoxic conditions, which makes it a potential target for cancer therapy. |
CAS号 | N/A |
分子量 | 61.8 KDa |
SMILES Code | NONE |
别名 | 重组人PFKFB3蛋白(E.coli, N-6His) ;Recombinant Human PFKFB3 (N-6His) |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |