货号:A2900885
同义名:
重组人NT-3蛋白(E.coli, tag free)
/ Recombinant Human NT-3; Neurotrophin-3
Recombinant Human NT-3是人源蛋白,在大肠杆菌中表达,无标签。该蛋白是神经营养因子-3,属于NGF家族成员,与β-NGF、BDNF和NT-4结构相关,成熟区为119个氨基酸,人、小鼠和大鼠的成熟序列一致。Recombinant Human NT-3可选择性促进中枢及外周神经系统中特定神经元亚群的存活与分化。


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| 描述 | Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Tyr139-Thr257 |
| 蛋白编号 | P20783 |
| 内毒素 | < 0.01 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 13.6 KDa |
| SMILES Code | NONE |
| 别名 | 重组人NT-3蛋白(E.coli, tag free) ;Recombinant Human NT-3; Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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