货号:A2900805
同义名:
重组人/小鼠/大鼠Activin A蛋白(HEK293, tag free)
/ Recombinant Human/Mouse/Rat Activin A; Inhibin beta A chain
Recombinant Human/Mouse/Rat Activin A是人/小鼠/大鼠来源的重组蛋白,在人源细胞中表达,无标签。该蛋白是激活素家族成员,属于TGF-β超家族,为二硫键连接的二聚体,最初从生殖液中分离获得,具有刺激垂体促卵泡激素(FSH)释放的作用,参与调控下丘脑与垂体激素分泌、生殖细胞发育、红细胞分化、神经细胞存活及胚胎发育等多种生物学功能。


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| 描述 | Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. |
| 蛋白种属 | Human/Mouse/Rat |
| 表达系统 | Human Cells |
| 标签 | Tag free |
| 蛋白表达区间 | Gly311-Ser426 |
| 蛋白编号 | P08476 |
| 内毒素 | < 0.01 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 13 KDa |
| SMILES Code | NONE |
| 别名 | 重组人/小鼠/大鼠Activin A蛋白(HEK293, tag free) ;Recombinant Human/Mouse/Rat Activin A; Inhibin beta A chain; INHBA; Activin A |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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