货号:A2900752
同义名:
重组人/小鼠FGF-8b蛋白(E.coli, tag free)
/ Recombinant Human/Mouse FGF-8b; Fibroblast growth factor 8
Recombinant Human/Mouse FGF-8b是人源/小鼠源重组蛋白,在大肠杆菌中表达,为无标签形式。该蛋白是成纤维细胞生长因子家族成员,与小鼠FGF-8b具有100%氨基酸同源性,广泛表达于胚胎发育阶段,介导上皮-间质转化,参与调控胚胎发育、细胞增殖、分化和迁移,对正常脑、眼、耳、四肢及促性腺激素释放激素神经元系统的发育具有重要作用。


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| 描述 | Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Mouse FGF8b shares 100% aa identity with human FGF8b. FGF8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
| 蛋白种属 | Human/Mouse |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Gln23-Arg215 |
| 蛋白编号 | P55075-3/P37237-2 |
| 内毒素 | < 0.01 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,300mM NaCl,2% Sucrose,0.02% Tween 80,pH7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 22.5 KDa |
| SMILES Code | NONE |
| 别名 | 重组人/小鼠FGF-8b蛋白(E.coli, tag free) ;Recombinant Human/Mouse FGF-8b; Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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