Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human LAG-3 (C-6His, HEK293)(Leu23-Gly434) 技术信息
CAS号
N/A
分子量
45.5 KDa
SMILES Code
NONE
别名
重组人LAG-3蛋白(C-6His, HEK293)(Leu23-Gly434)
;Recombinant Human LAG-3 (C-6His, HEK293)(Leu23-Gly434); Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human LAG-3 (C-6His, HEK293)(Leu23-Gly434)
|Human LAG-3 (C-6His, HEK293)(Leu23-Gly434)
| 重组人LAG-3蛋白(C-6His, HEK293)(Leu23-Gly434)
| Recombinant Human LAG-3 (C-6His, HEK293)(Leu23-Gly434)
| Lymphocyte activation gene 3 protein
| LAG3
| LAG-3
| Protein FDC
| CD223
| N/A
| Macrophage CD Proteins
| Immune Checkpoint Proteins
| NK Cell CD Proteins
| Human LAG-3 (C-6His, HEK293)(Leu23-Gly434) 纯度/质量文件
| Human LAG-3 (C-6His, HEK293)(Leu23-Gly434) 生物活性
| Human LAG-3 (C-6His, HEK293)(Leu23-Gly434) 技术信息
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