Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His) 技术信息
CAS号
N/A
分子量
18.4 KDa
SMILES Code
NONE
别名
重组人IL-7蛋白(HEK293, C-6His)
;Recombinant Human IL-7 (C-6His); Interleukin-7; IL-7; IL7
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His)
|Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His)
| 重组人IL-7蛋白(HEK293, C-6His)
| Recombinant Human IL-7 (C-6His)
| Interleukin-7
| IL-7
| IL7
| N/A
| Interleukin & Receptors
| 干细胞诱导
| Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His) 纯度/质量文件
| Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His) 生物活性
| Human IL-7 (C-6His)/人IL-7蛋白(HEK293, C-6His) 技术信息
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