Human IL-6/人IL-6蛋白(E.coli, tag free)
{[allProObj[0].p_purity_real_show]}
货号：A2900800同义名：
重组人IL-6蛋白(E.coli, tag free)
/ Recombinant Human IL-6; Interleukin-6
Recombinant Human IL-6是人源白细胞介素6蛋白，在大肠杆菌中表达，为无标签蛋白。该蛋白属于IL6/GCSF/MGF家族，是一种含约170至180个氨基酸残基的糖蛋白，具有两个二硫键稳定其球状结构，第四α螺旋对其生物活性至关重要。IL-6是一种重要的促炎和免疫调节细胞因子，可由多种细胞表达，能够抑制早期黑色素瘤细胞生长并促进晚期细胞增殖。
Human IL-6/人IL-6蛋白(E.coli, tag free) 化学结构 CAS号：N/A
Human IL-6/人IL-6蛋白(E.coli, tag free) 3D分子结构 CAS号：N/A
Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Sucorse, 4% Mannitol, 0.05% PS-80, pH7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
搜索
