Human IL-15/人IL-15蛋白(E.coli, tag free)
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货号：A2900780同义名：
重组人IL-15蛋白(E.coli, tag free)
/ Recombinant Human IL-15; Interleukin-15
Recombinant Human IL-15是人源白细胞介素15蛋白，在大肠杆菌中表达，为无标签形式。该蛋白是一种调节T细胞和自然杀伤细胞活化与增殖的细胞因子，高亲和力结合IL-15RAα亚基，同时结合IL-2受体的β和γ链但不结合α亚基，与IL-2在结构和功能上相关但具有独特免疫作用，主要由单核细胞、巨噬细胞和树突状细胞等组成性表达。
Human IL-15/人IL-15蛋白(E.coli, tag free) 化学结构 CAS号：N/A
Human IL-15/人IL-15蛋白(E.coli, tag free) 3D分子结构 CAS号：N/A
Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IL-15/人IL-15蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
12.5 KDa
SMILES Code
NONE
别名
重组人IL-15蛋白(E.coli, tag free)
;Recombinant Human IL-15; Interleukin-15; IL-15; IL15
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IL-15/人IL-15蛋白(E.coli, tag free)
|Human IL-15/人IL-15蛋白(E.coli, tag free)
| 重组人IL-15蛋白(E.coli, tag free)
| Recombinant Human IL-15
| Interleukin-15
| IL-15
| IL15
| N/A
| Interleukin & Receptors
| 干细胞诱导
| Human IL-15/人IL-15蛋白(E.coli, tag free) 纯度/质量文件
| Human IL-15/人IL-15蛋白(E.coli, tag free) 生物活性
| Human IL-15/人IL-15蛋白(E.coli, tag free) 技术信息
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