Human IL-10/人IL-10蛋白(HEK293, tag free)
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货号：A2900775同义名：
重组人IL-10蛋白(HEK293, tag free)
/ Recombinant Human IL-10; Interleukin-10
Recombinant Human IL-10是人源蛋白，在人源细胞中表达，无标签。该蛋白又称细胞因子合成抑制因子（CSIF），属于IL-10家族，是一种分泌型蛋白，主要由活化的造血细胞及肝星状细胞、角质形成细胞和胎盘细胞滋养层细胞分泌。作为抗炎TH2型细胞因子，它在调控免疫反应、抑制过度炎症反应中发挥关键作用，具有成为治疗性分子和疾病生物标志物的潜力。
Human IL-10/人IL-10蛋白(HEK293, tag free) 化学结构 CAS号：N/A
Human IL-10/人IL-10蛋白(HEK293, tag free) 3D分子结构 CAS号：N/A
Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations, it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed, IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation, it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection, high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IL-10/人IL-10蛋白(HEK293, tag free) 技术信息
CAS号
N/A
分子量
18.6 KDa
SMILES Code
NONE
别名
重组人IL-10蛋白(HEK293, tag free)
;Recombinant Human IL-10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10; RP11-262N9.1; IL10A; MGC126450; MGC126451; TGIF
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IL-10/人IL-10蛋白(HEK293, tag free)
|Human IL-10/人IL-10蛋白(HEK293, tag free)
| 重组人IL-10蛋白(HEK293, tag free)
| Recombinant Human IL-10
| Interleukin-10
| IL-10
| Cytokine synthesis inhibitory factor
| CSIF
| IL10
| RP11-262N9.1
| IL10A
| MGC126450
| MGC126451
| TGIF
| N/A
| Interleukin & Receptors
| 干细胞诱导
| Human IL-10/人IL-10蛋白(HEK293, tag free) 纯度/质量文件
| Human IL-10/人IL-10蛋白(HEK293, tag free) 生物活性
| Human IL-10/人IL-10蛋白(HEK293, tag free) 技术信息
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