产品名称：Recombinant Human IL-10理论分子量：18.6 KDa蛋白种属：Human表达系统：Human Cells蛋白表达区间：Ser19-Asn178标签：Tag free剂型：干粉纯度：≥95% as determined by reducing SDS-PAGE.储存条件：冻干蛋白应储存在≤-20°C，收到后可稳定保存一年。
溶解后的蛋白溶液可以在2-8°C下保存2-7天。如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。产品背景：Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations, it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed, IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation, it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection, high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations
Human IL-10/人IL-10蛋白(HEK293, tag free) 技术信息
CAS号
N/A
分子量
18.6 KDa
SMILES Code
NONE
别名
重组人IL-10蛋白(HEK293, tag free)
;Recombinant Human IL-10
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human IL-10/人IL-10蛋白(HEK293, tag free)
|Human IL-10/人IL-10蛋白(HEK293, tag free)
| 重组人IL-10蛋白(HEK293, tag free)
| Recombinant Human IL-10
| N/A
| Interleukin & Receptors
| 干细胞诱导
| Human IL-10/人IL-10蛋白(HEK293, tag free) 纯度/质量文件
| Human IL-10/人IL-10蛋白(HEK293, tag free) 生物活性
| Human IL-10/人IL-10蛋白(HEK293, tag free) 技术信息
搜索
