Human IGF-I/人IGF-I蛋白(E.coli, tag free)
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货号：A2900819同义名：
重组人IGF-I蛋白(E.coli, tag free)
/ Recombinant Human IGF-I; Insulin-Like Growth Factor I
Recombinant Human IGF-I是人源胰岛素样生长因子I，在大肠杆菌中表达，为无标签蛋白。该蛋白属于胰岛素样生长因子家族，成熟的人源IGF-I含70个氨基酸，与小鼠IGF-I有94%同源性并具有跨物种活性，通过与IGF-IR、IGF-IIR及胰岛素受体结合，参与调控细胞周期、增殖及肿瘤进展，其表达受生长激素调节。
Human IGF-I/人IGF-I蛋白(E.coli, tag free) 化学结构 CAS号：N/A
Human IGF-I/人IGF-I蛋白(E.coli, tag free) 3D分子结构 CAS号：N/A
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro.
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in 50mM Acetic Acid.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IGF-I/人IGF-I蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
7.6 KDa
SMILES Code
NONE
别名
重组人IGF-I蛋白(E.coli, tag free)
;Recombinant Human IGF-I; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IGF-I/人IGF-I蛋白(E.coli, tag free)
|Human IGF-I/人IGF-I蛋白(E.coli, tag free)
| 重组人IGF-I蛋白(E.coli, tag free)
| Recombinant Human IGF-I
| Insulin-Like Growth Factor I
| IGF-I
| Mechano Growth Factor
| MGF
| Somatomedin-C
| IGF1
| IBP1
| N/A
| IGF family
| 干细胞诱导
| Human IGF-I/人IGF-I蛋白(E.coli, tag free) 纯度/质量文件
| Human IGF-I/人IGF-I蛋白(E.coli, tag free) 生物活性
| Human IGF-I/人IGF-I蛋白(E.coli, tag free) 技术信息
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