Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human GDNF/人GDNF蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
15.1 KDa
SMILES Code
NONE
别名
重组人GDNF蛋白(E.coli, tag free)
;Recombinant Human GDNF; Glial Cell Line-Derived Neurotrophic Factor; hGDNF; Astrocyte-Derived Trophic Factor; ATF; GDNF
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human GDNF/人GDNF蛋白(E.coli, tag free)
|Human GDNF/人GDNF蛋白(E.coli, tag free)
| 重组人GDNF蛋白(E.coli, tag free)
| Recombinant Human GDNF
| Glial Cell Line-Derived Neurotrophic Factor
| hGDNF
| Astrocyte-Derived Trophic Factor
| ATF
| GDNF
| N/A
| Neurotrophic Factors
| TGF-beta Superfamily
| 干细胞诱导
| Human GDNF/人GDNF蛋白(E.coli, tag free) 纯度/质量文件
| Human GDNF/人GDNF蛋白(E.coli, tag free) 生物活性
| Human GDNF/人GDNF蛋白(E.coli, tag free) 技术信息
搜索
