Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 质控信息
Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 生物活性
描述
Immunoglobulin α Fc Receptor (IgA Fc Receptor) is a member of the immunoglobulin gene superfamily. It is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens through the charged arginin residue within its transmembrane domain. IgA Fc Receptor binds both IgA1 and IgA2 with similar affinity. The site of interaction between FCAR and IgA was identified in the first extracellular domain of FCAR and the C2/C3 junction of IgA. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is also expressed on Kupffer cells in the liver, where it was suggested to provide a second line of defense.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
24.52 KDa
SMILES Code
NONE
别名
重组人FcAR蛋白(C-6His, HEK293)
;Recombinant Human FcAR (C-6His, HEK293); Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293)
|Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293)
| 重组人FcAR蛋白(C-6His, HEK293)
| Recombinant Human FcAR (C-6His, HEK293)
| Immunoglobulin Alpha Fc Receptor
| IgA Fc Receptor
| CD89
| FCAR
| N/A
| Macrophage CD Proteins
| Fc alpha RI/CD89
| Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 纯度/质量文件
| Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 生物活性
| Human FcAR (C-6His, HEK293)/人FcAR蛋白(C-6His, HEK293) 技术信息
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