Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli)
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货号：A2924785同义名：
重组人ER alpha蛋白(N-6His, E.coli)
/ Recombinant Human ER alpha (N-6His, E.coli); Estrogen Receptor
Recombinant Human ER alpha (N-6His, E.coli) 是人源雌激素受体α蛋白，在大肠杆菌中表达，带有N端6×His标签。该蛋白属于核激素受体超家族，是重要的配体激活转录因子，参与激素结合、DNA结合及转录激活，主要定位于细胞核，可形成同源或异源二聚体。雌激素及其受体对生殖发育、骨骼健康至关重要，也与乳腺癌、子宫内膜癌及骨质疏松等病理过程相关。
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 化学结构 CAS号：N/A
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 3D分子结构 CAS号：N/A
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 质控信息
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 生物活性
描述
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Lyophilized from a 0.2 μm filtered solution of 20mM Glycine-HCl, 8% Sucrose, 0.05% Tween 80, pH 3.5.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 技术信息
CAS号
N/A
分子量
14.38 KDa
SMILES Code
NONE
别名
重组人ER alpha蛋白(N-6His, E.coli)
;Recombinant Human ER alpha (N-6His, E.coli); Estrogen Receptor; ER; ER-Alpha; Estradiol Receptor; Nuclear Receptor Subfamily 3 Group A Member 1; ESR1; ESR; NR3A1; Estrogen Receptor Alpha; ER alpha; estrogen receptor alpha
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli)
|Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli)
| 重组人ER alpha蛋白(N-6His, E.coli)
| Recombinant Human ER alpha (N-6His, E.coli)
| Estrogen Receptor
| ER
| ER-Alpha
| Estradiol Receptor
| Nuclear Receptor Subfamily 3 Group A Member 1
| ESR1
| ESR
| NR3A1
| Estrogen Receptor Alpha
| ER alpha
| estrogen receptor alpha
| N/A
| Nuclear Receptor Superfamily
| Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 纯度/质量文件
| Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 生物活性
| Human ER alpha (N-6His, E.coli)/人ER alpha蛋白(N-6His, E.coli) 技术信息
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