Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 6% Sucrose, 4% Mannitol, 0.05% Tween 80, pH 8.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CNTF/人CNTF蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
22.93 KDa
SMILES Code
NONE
别名
重组人CNTF蛋白(E.coli, tag free)
;Recombinant Human CNTF; Ciliary Neurotrophic Factor; CNTF
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human CNTF/人CNTF蛋白(E.coli, tag free)
|Human CNTF/人CNTF蛋白(E.coli, tag free)
| 重组人CNTF蛋白(E.coli, tag free)
| Recombinant Human CNTF
| Ciliary Neurotrophic Factor
| CNTF
| N/A
| Neurotrophic Factors
| 干细胞诱导
| Human CNTF/人CNTF蛋白(E.coli, tag free) 纯度/质量文件
| Human CNTF/人CNTF蛋白(E.coli, tag free) 生物活性
| Human CNTF/人CNTF蛋白(E.coli, tag free) 技术信息
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