Human CDCP1 (C-6His, HEK293)(Phe30-Ser341)
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货号：A2926621同义名：
重组人CDCP1蛋白(C-6His, HEK293)(Phe30-Ser341)
/ Recombinant Human CDCP1 (C-6His, HEK293)(Phe30-Ser341); CUB domain-containing protein 1
Recombinant Human CDCP1 (C-6His, HEK293)(Phe30-Ser341)是人类来源的重组蛋白，在HEK293细胞中表达，带有C端6×His标签。该蛋白为含CUB结构域蛋白1（CDCP1），是一种跨膜糖蛋白，具有含两个CUB结构域的大胞外域和含五个酪氨酸的小胞内域，广泛表达于人类上皮组织，其酪氨酸磷酸化与细胞粘附负调控相关，过表达可导致细胞粘附丧失及脱落表型。
Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 化学结构 CAS号：N/A
Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 3D分子结构 CAS号：N/A
CUB domain-containing protein 1(CDCP1) is a transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsinor EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 技术信息
CAS号
N/A
分子量
36.1 KDa
SMILES Code
NONE
别名
重组人CDCP1蛋白(C-6His, HEK293)(Phe30-Ser341)
;Recombinant Human CDCP1 (C-6His, HEK293)(Phe30-Ser341); CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318; TRASK
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human CDCP1 (C-6His, HEK293)(Phe30-Ser341)
|Human CDCP1 (C-6His, HEK293)(Phe30-Ser341)
| 重组人CDCP1蛋白(C-6His, HEK293)(Phe30-Ser341)
| Recombinant Human CDCP1 (C-6His, HEK293)(Phe30-Ser341)
| CUB domain-containing protein 1
| Membrane glycoprotein gp140
| Subtractive immunization M plus HEp3-associated 135 kDa protein
| SIMA135
| Transmembrane and associated with src kinases
| CD318
| TRASK
| N/A
| Epithelial cell CD Proteins
| Stem Cell CD Proteins
| Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 纯度/质量文件
| Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 生物活性
| Human CDCP1 (C-6His, HEK293)(Phe30-Ser341) 技术信息
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