货号:A2926490
同义名:
重组人CD37蛋白(C-Fc, HEK293)
/ Recombinant Human CD37 (C-Fc, HEK293); Leukocyte antigen CD37
Recombinant Human CD37 (C-Fc, HEK293) 是人源CD37蛋白,在HEK293人源细胞中表达,带有C-Fc标签。该蛋白属于跨膜4超家族(TM4SF)四跨膜蛋白,包含四个潜在跨膜区、两个胞外环及短胞质尾,主要表达于发育中的B细胞(从前B细胞到成熟外周B细胞阶段),但不表达于浆细胞。其参与细胞粘附、迁移、分化、增殖、转移、生长、存活、通过外泌体的细胞间通讯及免疫应答等多种生物学过程。


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| 描述 | CD37 is a member of the transmembrane 4 superfamily (TM4SF) of tetraspanin proteins. It consists of four potential membrane-spanning regions, two extracellular loops and short intracytoplasmatic tails. CD37 is expressed on developing B-cells from pre-B, peripheral mature B-cell stages, but not plasma cells. The involvement of CD37 (TSPAN26) protein in various biological processes including cell adhesion, motility, differentiation, proliferation, metastasis, growth, survival, trafficking, intercellular communication via exosomes and immune responses is well recognized. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-Fc |
| 蛋白表达区间 | Thr110-Asn241 |
| 蛋白编号 | P11049 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 42 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CD37蛋白(C-Fc, HEK293) ;Recombinant Human CD37 (C-Fc, HEK293); Leukocyte antigen CD37; Tetraspanin-26; TSPAN26; CD37 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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