Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 质控信息
Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 生物活性
描述
The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 0.05% Tween80, pH8.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 技术信息
CAS号
N/A
分子量
46 KDa
SMILES Code
NONE
别名
重组人ANGPTL8蛋白(N-Fc, HEK293)
;Recombinant Human ANGPTL8 (N-Fc, HEK293); Betatrophin; Angiopoietin-like protein 8; Lipasin; Angptl8
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293)
|Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293)
| 重组人ANGPTL8蛋白(N-Fc, HEK293)
| Recombinant Human ANGPTL8 (N-Fc, HEK293)
| Betatrophin
| Angiopoietin-like protein 8
| Lipasin
| Angptl8
| N/A
| Angiopoietins
| Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 纯度/质量文件
| Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 生物活性
| Human ANGPTL8 (N-Fc, HEK293)/人ANGPTL8蛋白(N-Fc, HEK293) 技术信息
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