Human ANGPTL8 (N-Fc, HEK293)
产品说明书
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同义名 : | 重组人ANGPTL8蛋白(N-Fc, HEK293) ;Recombinant Human ANGPTL8 (N-Fc, HEK293); Betatrophin; Angiopoietin-like protein 8; Lipasin; Angptl8 |
| CAS号 : | N/A | |
| 货号 : | A2924579 | |
| 分子式 : | - | |
| 纯度 : | 70% determined by reducing SDS-PAGE. | |
| 分子量 : | 46 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes. | ||