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Docusate Sodium/多库酯钠 {[allProObj[0].p_purity_real_show]}

货号:A571244 同义名: 多库酯钠 / Dioctyl sulfosuccinate sodium salt; Docusate (sodium salt)

Dioctyl sulfosuccinate sodium salt is a surfactant used to prepare reverse micelles.

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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Docusate Sodium/多库酯钠 化学结构 CAS号:577-11-7
Docusate Sodium/多库酯钠 化学结构
CAS号:577-11-7
Docusate Sodium/多库酯钠 3D分子结构
CAS号:577-11-7
Docusate Sodium/多库酯钠 化学结构 CAS号:577-11-7
Docusate Sodium/多库酯钠 3D分子结构 CAS号:577-11-7
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Docusate Sodium/多库酯钠 纯度/质量文件 产品仅供科研

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Docusate Sodium/多库酯钠 生物活性

描述 Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is primarily utilized in stool softeners and functions as a sulfated surfactant. It has the potential to inactivate viral pathogens by disrupting their envelopes or by denaturing/disassociating proteins. Docusate Sodium has shown efficacy in vitro against both wild type and drug-resistant strains of HSV types 1 and 2. Furthermore, it is classified as an obesogen, with developmental exposure leading to increased adult adiposity, inflammation, metabolic disorders, and dyslipidemia in offspring fed a standard diet in mice[1].[2].
体内研究

In experiments with mice, Docusate Sodium administered to dams at a concentration of 31.25 μg/mL (dissolved in water) resulted in increased body mass, fat mass, fat percentage, and reduced bone area in adult F1 male offspring[2].

Docusate Sodium/多库酯钠 参考文献

[1]Y Gong, et al. Preclinical evaluation of docusate as protective agent from herpes simplex viruses. Antiviral Res. 2001 Oct;52(1):25-32.

[2]Alexis M Temkin, et al. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 Feb 6;9(1):1530.

Docusate Sodium/多库酯钠 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.25mL

0.45mL

0.22mL

11.25mL

2.25mL

1.12mL

22.49mL

4.50mL

2.25mL

Docusate Sodium/多库酯钠 技术信息

CAS号577-11-7
分子式C20H37NaO7S
分子量 444.56
SMILES Code O=S(C(CC(OCC(CC)CCCC)=O)C(OCC(CC)CCCC)=O)([O-])=O.[Na+]
MDL No. MFCD00012455
别名 多库酯钠 ;Dioctyl sulfosuccinate sodium salt; Docusate (sodium salt); KM 10-1610; DOSS; Dioctyl sulfosuccinate; AOT; Constonate; Bis(2-ethylhexyl) sulfosuccinate sodium salt; Aerosol OT
运输蓝冰
InChI Key APSBXTVYXVQYAB-UHFFFAOYSA-M
Pubchem ID 23673837
存储条件

In solvent -20°C:3-6个月-80°C:12个月

溶解方案

H2O: 20 mg/mL(44.99 mM)

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