The DNA methyltransferase (DNMT) family are enzymes that can mediate the DNA methylation. Inhibiting the DNMTs have shown particular promise in reducing the formation of tumors[5]. The decitabine is a potent inhibitor of the DNA methylation with IC50 value of 100 and 10 ng/ml for 72 and 96h of exposure on both HL-60 and KG1a leukemic cells[6].
The human aortic smooth muscle cells (HASMCs) were treated with decitabine for 48 hours. The DNMT1 expression measured by western blotting assay in the nuclear fraction was reduced by the decitabine. The expression of the osteogenic genes ALP, Max2, BMP2, Pit-1, SM22 and -SMA in HASMCs measured by RT-qPCR was increased by decitabine[7]. The hyperoxia-indued lung injury Sprague-Dawley rats were injected with decitabine at a dose of 0.5 mg/kg/day for 14 days. The survival rate of the treatment group was significantly higher than the hyperoxia group. The P16 methylation rate in the lung tissues measured by PCR was induced by the hyperoxia and the decitabine could effectively reverse the hypermethylation of P16[8].
作用机制
Decitabine could combine with DNA during DNA replication and form covalent complexes with the DNMT1. Therefore, the methyl transfer activity of the enzyme is inhibited[8].
Decitabine/地西他宾 细胞实验
Cell Line
Concentration
Treated Time
Description
References
MOLM13 cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC significantly reduced cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
MV4;11 cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC significantly reduced cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
NALM-6 cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC significantly reduced cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
REH cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC significantly reduced cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
RS4;11 cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC had minimal effect on cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
SEM cells
100 nM
72 hours
Assessed proliferation and metabolic activity, DEC significantly reduced cell counts and metabolism
Mol Oncol. 2025 May;19(5):1404-1421
SW620 cells
2.5 μM and 5 μM
72 hours
To investigate the activation of PEPT1 transcription by DAC, results showed DAC activated PEPT1 transcription in a dose-dependent manner.
Cell Death Dis. 2021 May 24;12(6):532.
SW480 cells
2.5 μM and 5 μM
72 hours
To investigate the activation of PEPT1 transcription by DAC, results showed DAC activated PEPT1 transcription in a dose-dependent manner.
Cell Death Dis. 2021 May 24;12(6):532.
MTT cells
10^-4 mol/L VPA and 10^-7 mol/L DAC
2 days
Investigate the effects of VPA and DAC on SSTR2 levels and radioligand uptake in MTT cells. Results showed that the combination of VPA and DAC significantly increased SSTR2 levels and radioligand uptake.
Theranostics. 2023 Jan 1;13(1):278-294.
MPC cells
10^-4 mol/L VPA and 10^-7 mol/L DAC
2 days
Investigate the effects of VPA and DAC on SSTR2 levels and radioligand uptake in MPC cells. Results showed that DAC alone or in combination with VPA increased SSTR2 levels and radioligand uptake.
Theranostics. 2023 Jan 1;13(1):278-294.
Human umbilical vein endothelial cells (HUVECs)
10 μmol/L
24 hours
Inhibition of DNMTs suppressed the disturbed flow/OS-induced EndoMT and ameliorated the downregulation of ALDHs and β-alanine biosynthesis.
Theranostics. 2023 Aug 6;13(13):4392-4411
HCT116 cells
2.5 μM
24–72 h
Inhibited methylation and increased HOXB13 expression
Signal Transduct Target Ther. 2019 Nov 29;4:51.
RKO cells
2.5 μM
24–72 h
Inhibited methylation and increased HOXB13 expression
Signal Transduct Target Ther. 2019 Nov 29;4:51.
Alb-R26Met HCC cells
0.3 µM
48 h
Decitabine treatment does not affect the viability of Alb-R26Met HCC cells but interferes with their tumorigenic properties, as evidenced by reduced colony numbers in anchorage-independent growth, reduced number and size of foci in anchorage-dependent growth, and reduced tumor spheres in self-renewal conditions.
Nat Commun. 2018 Aug 8;9(1):3164.
T-ALL cells
1 μM
48 h
To evaluate the effect of Decitabine on T-ALL cell lines, results showed that Decitabine significantly upregulated tumor suppressor genes (e.g., BMF and BBC3) and downregulated the MYC pathway.
Blood Cancer Discov. 2020 Nov;1(3):274-289.
HGC27 cells
20μM
72 h
Decitabine synergized with COX inhibitors to reduce cell viability in HGC27 cells
Theranostics. 2019 Aug 14;9(21):6256-6268.
MKN1 cells
20μM
72 h
Decitabine synergized with COX inhibitors to reduce cell viability in MKN1 cells
Theranostics. 2019 Aug 14;9(21):6256-6268.
PUER cells
0.5 µM
Decitabine addition concurrent with OHT attenuated the repression of stem cell genes and the activation of differentiation genes, thereby maintaining self-renewal of hematopoietic precursors
Mol Cancer Ther. 2010 Jun;9(6):1536-43.
Human CD34+ hematopoietic precursors
0.5 µM
Decitabine addition concurrent with G-CSF attenuated the repression of stem cell genes and the activation of differentiation genes, thereby maintaining self-renewal of hematopoietic precursors
Mol Cancer Ther. 2010 Jun;9(6):1536-43.
ML-2 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
K562 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
U937 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
HL-60 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
KG-1 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
KG-1a cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
HCT116 cells
100 nM
24 h
Quantitative determination of Decitabine incorporation into DNA, showing significant incorporation of Decitabine
Nucleic Acids Res. 2014 Oct 29;42(19):e152.
Decitabine/地西他宾 动物实验
Species
Animal Model
Administration
Dosage
Frequency
Description
References
Mice
SEM-fluc and RS4;11-fluc cell line-derived xenograft models
Intraperitoneal injection
0.4 mg/kg
4 consecutive days starting 7 days after tumor cell injection
Assessed the effect of DEC on tumor cell proliferation, DEC significantly delayed tumor cell proliferation
Mol Oncol. 2025 May;19(5):1404-1421
Mice
MC38 tumor model
Intraperitoneal injection
0.2 mg/kg/day
5 consecutive days
DAC combined with anti-PD-1 significantly inhibited tumor growth, promoted TILs infiltration, and enhanced CD8+ T cell function
Mol Cancer. 2023 May 16;22(1):84
Mice
Endothelial lineage tracing mice and conditional EC Dnmt1 knockout mice
Intraperitoneal injection
0.2 mg/kg
6 consecutive days of injection and 1 day of rest as intervals for 3 weeks
Endothelial-specific knockout of Dnmt1 protected the vasculature from disturbed flow-induced remodeling and atherosclerosis.
Theranostics. 2023 Aug 6;13(13):4392-4411
CD-1 mice
Not specified
Oral gavage
0.4 mg/kg and 1.0 mg/kg
Single dose
To measure plasma drug levels of Decitabine, results showed significantly lower drug levels in male mice compared to females
Clin Cancer Res. 2013 Feb 15;19(4):938-48
Nude mice
Alb-R26Met HCC cell xenograft model
Intraperitoneal injection
2.5 mg/kg
Twice a week for three weeks
Decitabine treatment significantly reduced the tumor volume of Alb-R26Met HCC cells in nude mice, and the dose was not toxic.
Nat Commun. 2018 Aug 8;9(1):3164.
Mice
T-ALL patient-derived xenograft (PDX) models
Not specified
0.5 mg/kg
Once daily for 5 days, followed by 2 days off, for two cycles
To evaluate the effect of Decitabine on T-ALL xenograft models, results showed that Decitabine significantly prolonged leukemia-free survival and downregulated the MYC pathway.
Blood Cancer Discov. 2020 Nov;1(3):274-289.
Nude mice
HGC27 xenograft model
Intraperitoneal injection
5mg/kg
3 times per week for 21 days
Decitabine synergized with Celecoxib to inhibit HGC27 xenograft tumor growth
United States, Ohio
... 展开 >>
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
United States, Texas
M D Anderson Cancer Center
Houston, Texas, United States, 77030 收起 <<
United States, New York
... 展开 >>
51 West 51st Street, Suite 200
Recruiting
New York, New York, United States, 10019
Contact: Michelle Malanga 212-326-5731 mm4629@cumc.columbia.edu
Italy
University of Bologna
Not yet recruiting
Bologna, Italy
Principal Investigator: Pier Luigi Zinzani, MD, PhD
Korea, Republic of
Samsung Medical Center
Not yet recruiting
Seoul, Korea, Republic of
Principal Investigator: Won Seog Kim, MD, PhD 收起 <<
United States, Ohio
... 展开 >>
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
United States, Texas
M D Anderson Cancer Center
Houston, Texas, United States, 77030 收起 <<
United States, New York
... 展开 >>
51 West 51st Street, Suite 200
Recruiting
New York, New York, United States, 10019
Contact: Michelle Malanga 212-326-5731 mm4629@cumc.columbia.edu
Italy
University of Bologna
Not yet recruiting
Bologna, Italy
Principal Investigator: Pier Luigi Zinzani, MD, PhD
Korea, Republic of
Samsung Medical Center
Not yet recruiting
Seoul, Korea, Republic of
Principal Investigator: Won Seog Kim, MD, PhD 收起 <<
United States, Montana
... 展开 >>
Bozeman Deaconess Hospital
Bozeman, Montana, United States, 59715
United States, Washington
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, United States, 99336
EvergreenHealth Medical Center
Kirkland, Washington, United States, 98033
Skagit Valley Hospital
Mount Vernon, Washington, United States, 98274
Olympic Medical Center
Port Angeles, Washington, United States, 98362
Group Health Cooperative
Redmond, Washington, United States, 98052
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
Multicare Health System
Tacoma, Washington, United States, 98415
Wenatchee Valley Hospital and Clinics
Wenatchee, Washington, United States, 98801 收起 <<
Primary Mediastinal Large B-ce... 展开 >>ll Lymphoma 收起 <<
Phase 1
Phase 2
Recruiting
October 1, 2019
China, Beijing
... 展开 >> Biotherapeutic Department and Pediatrics Department of Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Weidong Han, Doctor 86-10-66937463 hanwdrsw@sina.com
Contact: Qingming Yang, Doctor 86-10-55499341 yangqm@medmail.com.cn
Principal Investigator: Wenying Zhang
Principal Investigator: Qian Mei
Principal Investigator: Yang Liu
Principal Investigator: Weidong Han
Principal Investigator: Qingming Yang
Principal Investigator: Hejin Jia
Principal Investigator: Jing Nie
Principal Investigator: Chunmeng Wang
Principal Investigator: Yan Zhang
Sub-Investigator: Kaichao Feng
Sub-Investigator: Meixia Chen
Sub-Investigator: Lu Shi
Sub-Investigator: Xiang Li
Sub-Investigator: Liang Dong
Biotherapeutic Department of Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Weidong Han, Doctor 86-10-66937463 hanwdrsw@sina.com
Contact: Qingming Yang, Doctor 86-10-55499341 yangqm@medmail.com.cn 收起 <<
China
... 展开 >> Ruijin Hospital North
Not yet recruiting
Shanghai, China
Contact: Sujiang Zhang, MD 0086-21-67888761 zbruce.zhang@hotmail.com
Principal Investigator: Sujiang Zhang, MD
Ruijin Hospital
Not yet recruiting
Shanghai, China
Contact: Junmin Li, MD 86-21-64370045 ext 665251 drlijunming@126.com
Principal Investigator: Junming Li, MD
Shanghai Institute of Hematology
Not yet recruiting
Shanghai, China
Contact: Min Lu, Ph.D. 86-21-64370045 ext 610805 min.lu@shsmu.edu.cn
Principal Investigator: Min Lu, Ph.D. 收起 <<
Terminated(The study was put o... 展开 >>n clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.) 收起 <<
-
United States, New York
... 展开 >>
Weill Cornell Medical College
New York, New York, United States, 10021 收起 <<
Acute Myeloid Leukemia (AML) W... 展开 >>ith Multilineage Dysplasia Following Myelodysplastic Syndrome, in Adults
AML (Adult) With 11q23 (MLL) Abnormalities
AML (Adult) With Del (5q)
AML (Adult) With Inv (16) (p13; q22)
AML (Adult) With t (16;16) (p13; q22)
AML (Adult) With t (8; 21) (q22; q22)
Secondary AML (Adult)
Untreated AML (Adult) 收起 <<
Phase 2
Terminated(Accrual factor)
-
United States, California
... 展开 >>
Stanford University School of Medicine
Stanford, California, United States, 94305 收起 <<
United States, Ohio
... 展开 >>
Gabrail Cancer Center
Canton, Ohio, United States, 44718
United States, Rhode Island
Landmark Medical Center
Woonsocket, Rhode Island, United States, 02895
United States, Tennessee
Sarah Cannon Research
Nashville, Tennessee, United States, 37203
United States, Texas
M. D. Anderson
Houston, Texas, United States, 77030 收起 <<
United States, Maryland
... 展开 >>
Johns Hopkins
Not yet recruiting
Baltimore, Maryland, United States, 21218
Contact: Amy DeZern, MD
Principal Investigator: Amy DeZern, MD
United States, Texas
US Oncology - Texas Oncology - Austin Midtown
Recruiting
Austin, Texas, United States, 78705
Contact: Jason Melear, MD 512-421-4163
Principal Investigator: Jason Melear, MD
US Oncology - Texas Oncology - San Antonio Medical Center
Recruiting
San Antonio, Texas, United States, 78240
Contact: Roger Lyons, MD
Principal Investigator: Roger Lyons, MD
US Oncology - Texas Oncology - Tyler
Recruiting
Tyler, Texas, United States, 75702
Contact: Habte Yimer, MD 903-579-9800
Principal Investigator: Habte Yimer, MD
United States, Washington
US Oncology - Northwest Cancer Specialists, P.C.
Recruiting
Vancouver, Washington, United States, 98684
Contact: David A Smith, MD
Principal Investigator: David A Smith, MD 收起 <<
United States, New York
... 展开 >>
University of Rochester
Recruiting
Rochester, New York, United States, 14642
Contact: Haley Misch 585-275-9485 Haley_Misch@urmc.rochester.edu
Contact: Robin Boerman 585-273-1507 Robin_Boerman@urmc.rochester.edu
Principal Investigator: Jane Liesveld, MD
Sub-Investigator: Kristen O'Dwyer, MD 收起 <<
Terminated(The study was put o... 展开 >>n clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.) 收起 <<
United States, Ohio
... 展开 >>
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
Columbus, Ohio, United States, 43210 收起 <<
United States, New Jersey
... 展开 >>
Hackensack University Medical Center - John Theurer Cancer Center
Hackensack, New Jersey, United States, 07601 收起 <<
Suspended(second DLT in cohort... 展开 >> experience. Cohort is closed and study is being amended in order to re-open) 收起 <<
November 2019
United States, Pennsylvania
... 展开 >>
Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, United States, 19171 收起 <<
United States, Ohio
... 展开 >>
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Withdrawn
Cleveland, Ohio, United States, 44106
Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center
Recruiting
Cleveland, Ohio, United States, 44195
Contact: Mitchell R Smith, MD, PhD 216-444-4366 smithm14@ccf.org
Principal Investigator: Mitchell R Smith, MD, PhD 收起 <<
United States, Washington
... 展开 >>
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, United States, 99336
EvergreenHealth Medical Center
Kirkland, Washington, United States, 98033
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109 收起 <<
China, Beijing
... 展开 >> Biotherapeutic Department of Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Wei D Han, Doctor +86-10-66937463 hanwdrsw@sina.com
Contact: Xue C Lu, Doctor +86-10-66876237 luxuechun@126.com
Sub-Investigator: Yang Liu, Master
Sub-Investigator: Bo Yang, Doctor
Sub-Investigator: Yao Wang, Master
Sub-Investigator: Yan Zhang, Doctor
Principal Investigator: Wei D Han, Doctor
Sub-Investigator: Xue C Lu, Doctor 收起 <<
United States, Connecticut
... 展开 >>
Boehringer Ingelheim Investigational Site
New Haven, Connecticut, United States
United States, Missouri
Boehringer Ingelheim Investigational Site
St. Louis, Missouri, United States
United States, New York
Boehringer Ingelheim Investigational Site
Lake Success, New York, United States
United States, Texas
Boehringer Ingelheim Investigational Site
Houston, Texas, United States 收起 <<
Acute Myeloid Leukemia With FL... 展开 >>T3/ITD Mutation
Blasts More Than 10 Percent of Bone Marrow Nucleated Cells
Blasts More Than 10 Percent of Peripheral Blood White Cells
Myelodysplastic Syndrome
Recurrent Acute Myeloid Leukemia
Recurrent Myelodysplastic Syndrome 收起 <<
Phase 1
Phase 2
Recruiting
January 1, 2020
United States, Texas
... 展开 >>
M D Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: Musa Yilmaz 713-745-9945
Principal Investigator: Musa Yilmaz 收起 <<
China, Beijing
... 展开 >> Biotherapeutic Department of Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Weidong Han, Doctor +86-10-66937463 hanwdrsw@sina.com
Contact: Qingming Yang, Doctor +86-10-55499341 yangqm@medmail.com.cn
Principal Investigator: Yang Liu, Doctor
Principal Investigator: Chunmeng Wang, Master
Principal Investigator: Wenying Zhang, Master
Principal Investigator: Meixia Chen, Doctor
Principal Investigator: Weidong Han, Doctor
Principal Investigator: Qingming Yang, Doctor
Principal Investigator: Qian Mei, Doctor
Principal Investigator: Jing Nie, Doctor
Sub-Investigator: Yan Zhang, Doctor
Sub-Investigator: Kaichao Feng, Doctor
Sub-Investigator: Jingdan Qiu, Doctor
Sub-Investigator: Hejin Jia, Doctor
Sub-Investigator: Xiang Li, Master
Sub-Investigator: Liang Dong, Master
Sub-Investigator: Lu Shi, Master 收起 <<
United States, Pennsylvania
... 展开 >>
Fox Chase Cancer Center
Recruiting
Philadelphia, Pennsylvania, United States, 19111
Contact: Philip Pancari, MD
Jeans Hospital
Recruiting
Philadelphia, Pennsylvania, United States, 19111
Contact: Philip Pancari, MD 收起 <<
Primary Malignant Neoplasm of ... 展开 >>Ovary
FIGO Stages II to IV 收起 <<
Phase 2
Phase 3
Recruiting
June 2024
China, Beijing
... 展开 >> Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Yan Zhang, Dr. 86-10-55499341 zhangyan@163.com
Principal Investigator: Yuanguang Meng, Professor 收起 <<
France
... 展开 >> CHU La Réunion - Site nord
Not yet recruiting
Saint-Denis, La Réunion, France, 97400
Contact: Tahar Touahri, MD tahar.touahri@chu-reunion.fr
Principal Investigator: Tahar Touahri, MD
CHU La Réunion-Site Sud
Not yet recruiting
Saint-Pierre, La Réunion, France, 97410
Contact: Patricia Zunic, MD patricia.zunic@chu-reunion.fr
Principal Investigator: Patricia Zunic, MD
Chu Amiens
Recruiting
Amiens, France, 80054
Contact: Lavinia Merlusca, MD 0322455915 merlusca.lavinia@chu-amiens.fr
Principal Investigator: Lavinia Merlusca, MD
CHU d'Angers
Recruiting
Angers, France, 49 000
Contact: Mathilde Hunault +33 2 41 35 44 75 MaHunault@chu-angers.fr
Principal Investigator: Mathilde Hunault, Professor
CH Victor Dupouy
Not yet recruiting
Argenteuil, France, 95107
Contact: Ahmad Al Jijakli, MD +33134232339 ahmad.aljijakli@ch-argenteuil.fr
Principal Investigator: Ahmad Al Jijakli, MD
Ch Avignon
Recruiting
Avignon, France, 84000
Contact: Bohrane Slama, MD 0432753132 bslama@ch-avignon.fr
Principal Investigator: Bohrane Slama, MD
Centre Hospitalier de La Cote Basque
Not yet recruiting
Bayonne, France, 64100
Contact: Anne Banos, MD 033559443832 abanos@ch-cotebasque.fr
Principal Investigator: Anne Banos, MD
Hôpital Nord Franche-Comté
Not yet recruiting
Belfort, France, 90015
Contact: Marius Moldovan, MD +33 3 84 98 23 17 marius.moldovan@hnfc.fr
Principal Investigator: Marius Moldovan, MD
Hôpital Avicenne
Recruiting
Bobigny, France, 93009
Contact: Thorsten Braun, MD (0) 33 1 48 95 70 51 thorsten.braun@avc.aphp.fr
Principal Investigator: Thorsten Braun, MD
CHU de Brest - Hôpital Morvan
Not yet recruiting
Brest, France, 29609
Contact: Jean-Richard Eveillard, MD 33 2 98 22 33 33 jean-richard.eveillard@chu-brest.fr
Principal Investigator: Jean-Richard Eveillard, MD
CHU Côte de Nacre
Recruiting
Caen, France, 14033
Contact: Stéphane CHEZE, MD 0033231272360 cheze-s@chu-caen.fr
Principal Investigator: Stéphane CHEZE, MD
Hôpital privé Sévigné
Recruiting
Cesson-Sévigné, France, 35510
Contact: Benoît Bareau, MD +33 2 23 21 05 50 benoit.bareau@gmail.com
Principal Investigator: Benoît Bareau, MD
CHU Estaing
Recruiting
Clermont-Ferrand, France, 63058
Contact: Benoit De RENZIS, MD 0334 73 75 00 65 bderenzis@chu-clermontferrand.fr
Principal Investigator: Benoit De RENZIS, MD
CH de Compiègne
Not yet recruiting
Compiègne, France, 60321
Contact: Sophie Dennetière, MD +33 3 44 23 63 47 s.dennetiere@ch-compiegnenoyon.fr
Principal Investigator: Sophie Dennetière, MD
Centre Hospitalier Sud-Francilien
Not yet recruiting
Corbeil-Essonnes, France, 91106
Contact: Célia Salanoubat, MD +33 1 60 90 31 78 celia.salanoubat@ch-sud-francilien.fr
Principal Investigator: Célia Salanoubat, MD
Centre Henri Mondor
Recruiting
Créteil, France, 94010
Contact: Andrea Toma, MD 0033149812057 andrea.toma@hmn.aphp.fr
Principal Investigator: Andrea Toma, MD
CHU Albert Michallon
Recruiting
Grenoble, France, 38043
Contact: Stéphane COURBY, MD 033 4 76 76 57 12 SCourby@chu-grenoble.fr
Principal Investigator: Stéphane COURBY, MD
Principal Investigator: Sophie Park, PHD
CH Le Mans
Recruiting
Le Mans, France, 72000
Contact: Kamel Laribi, MD 0243434361 klaribi@ch-lemans.fr
Principal Investigator: Kamel Laribi, MD
Clinique Victor Hugo
Not yet recruiting
Le Mans, France, 72000
Contact: Anne Parcelier, MD +33 2 43 47 94 93 a.parcelier@i-l-c.fr
Principal Investigator: Anne Parcelier, MD
Hôpital Saint Vincent de Paul
Not yet recruiting
Lille, France, 59020
Contact: Laurent Pascal, MD, PHD +33320874532 pascal.laurent@ghicl.net
Principal Investigator: Laurent Pascal, MD, PHD
CHRU de Limoges
Recruiting
Limoges, France, 87046
Contact: Marie-Pierre Gourin, MD 0033555056651 marie-pierre.gourin@chu-limoges.fr
Principal Investigator: Marie Pierre Gourin, MD
Centre Hospitalier Lyon Sud
Recruiting
Lyon, France, 69495
Contact: Eric WATTEL, PHD,MD 033 4 72 11 74 01 eric.wattel@chu-lyon.fr
Principal Investigator: Eric WATTEL, PHD,MD
Institut Paoli-Calmette
Recruiting
Marseille, France, 13009
Contact: Norbert VEY, PHD,MD 033 4 91 22 37 54 veyn@marseille.fnclcc.fr
Principal Investigator: Norbert VEY, PHD,MD
Centre Hospitalier de Meaux
Not yet recruiting
Meaux, France, 77100
Contact: Loïc Fouillard, MD 033164653876 l-fouillard@ch-meaux.fr
Principal Investigator: Loïc Fouillard, MD
Clinique Beausoleil
Not yet recruiting
Montpellier, France, 34000
Contact: Sophie Auger-Quittet, MD +33467759999 s.auger-quittet@languedoc-mutualite.fr
Principal Investigator: Sophie Auger-Quittet, MD
Hôpital Saint Eloi
Recruiting
Montpellier, France, 34295
Contact: Robert Navarro, MD +33467338362 r-navarro@chu-montpellier.fr
Principal Investigator: Robert Navarro, MD
Hopital de l'Hotel Dieu
Recruiting
Nantes, France, 44093
Contact: Pierre Peterlin, MD +33 2 40 08 32 71 pierre.peterlin@chu-nantes.fr
Principal Investigator: Pierre Peterlin, MD
Hopital Archet I
Not yet recruiting
Nice, France, 06202
Contact: Laurence LEGROS, MD 00 33 4 92 03 58 44 legros.l@chu-nice.fr
Principal Investigator: Laurence LEGROS, MD
CHU de Nîmes
Recruiting
Nîmes, France, 30029
Contact: Stefan Wickenhauser, MD +33 4 66 68 40 33 stefan.wickenhauser@chu-nimes.fr
Principal Investigator: Stefan Wickenhauser, MD
CHR d'Orléans
Recruiting
Orléans, France, 45067
Contact: Ali Arar, MD +33238229546 ali.arar@chr-orleans.fr
Principal Investigator: Ali Arar, MD
Hopital St Louis T4
Recruiting
Paris, France, 75475
Contact: Pierre Fenaux, PHD 0171207022 pierre.fenaux@sls.aphp.fr
Principal Investigator: Pierre Fenaux, PHD
Principal Investigator: ITZYKSON Raphael, MD
Centre Hospitalier Joffre
Recruiting
Perpignan, France, 66046
Contact: Laurence Sanhes, MD 00 33 468616448 laurence.sanhes@ch-perpignan.fr
Principal Investigator: Laurence Sanhes, MD
CHU de Haut-Lévèque
Not yet recruiting
Pessac, France, 33604
Contact: Sophie Dimicoli-Salazar, MD 033557656511 sophie.dimicoli-salazar@chu-bordeaux.fr
Principal Investigator: Sophie Dimicoli-Salazar, MD
CHU Poitiers
Recruiting
Poitiers, France, 86021
Contact: Jose Miguel Torregrosa Diaz, MD +33548444444 jose-miguel.torregrosa-diaz@chu-poitiers.fr
Principal Investigator: Jose Miguel Torregrosa Diaz, MD
CH René Dubos
Not yet recruiting
Pontoise, France, 95000
Contact: Riad Benramdane, MD +33156831442 benramdaner@yahoo.fr
Principal Investigator: Riad Benramdane, MD
CH Annecy Genevois
Not yet recruiting
Pringy, France, 74374
Contact: Pascale Cony-Makhoul, MD +33 4 50 63 64 31 pconymakhoul@ch-annecygenevois.fr
Principal Investigator: Pascale Cony-Makhoul, MD
CHU de Reims
Not yet recruiting
Reims, France, 51092
Contact: Chantal HIMBERLIN, MD 003326783644 chimberlin@chu-reims.fr
Principal Investigator: Chantal HIMBERLIN, MD
CHU Pontchaillou
Recruiting
Rennes, France, 35033
Contact: Stanislas Nimubona, MD 33299289521 stanislas.nimubona@chu-rennes.fr
Principal Investigator: Stanislas Nimubona, MD
Centre Henri Bequerel
Recruiting
Rouen, France, 76038
Contact: Aspasia STAMATOULLAS, MD 00 33 2 32 08 22 88 aspasia.stamatoullas@chb.unicancer.fr
Principal Investigator: Aspasia STAMATOULLAS, MD
Hôpital Hautepierre
Not yet recruiting
Strasbourg, France, 67098
Contact: Shanti Natarajan-Ame, MD +33388121670 shanti.ame@chru-strasbourg.fr
Principal Investigator: Shanti Natarajan-Ame, MD
IUCT Oncopole - Département d'hématologie
Not yet recruiting
Toulouse, France, 31059
Contact: Christian RECHER, MD, PHD 05 61 77 20 78 recher.christian@iuct-oncopole.fr
Principal Investigator: Christian RECHER, MD
Iuct Oncopole
Recruiting
Toulouse, France, 31059
Contact: Odile BEYNE-RAUZY, MD, PHD +33(0)5 31 15 62 64 beynerauzy.odile@iuct-oncopole.fr
Principal Investigator: Odile Beyne-Rauzy, PHD
CH Valence
Not yet recruiting
Valence, France, 26953
Contact: Jixing Liu, MD +33475757566 jliu@ch-valence.fr
Principal Investigator: Jixing Liu, MD
CHU Brabois
Not yet recruiting
Vandœuvre-lès-Nancy, France, 54511
Contact: Agnès GUERCI-BRESLER, MD 0033383153281 a.guerci@chu-nancy.fr
Principal Investigator: Agnès GUERCI-BRESLER, MD
Institut gustave Roussy
Not yet recruiting
Villejuif, France, 94805
Contact: Eric Solary, MD +33142114507 eric.solary@igr.fr
Principal Investigator: ERIC SOLARY, MD 收起 <<
Acute Myeloid Leukemia
... 展开 >> Blasts 5 Percent or More of Bone Marrow Nucleated Cells
Recurrent Adult Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
TP53 wt Allele
Untreated Adult Acute Myeloid Leukemia 收起 <<
Phase 1
Recruiting
October 31, 2019
United States, California
... 展开 >>
City of Hope Comprehensive Cancer Center
Recruiting
Duarte, California, United States, 91010
Contact: Site Public Contact 800-826-4673 becomingapatient@coh.org
Principal Investigator: Samer K. Khaled
Los Angeles County-USC Medical Center
Recruiting
Los Angeles, California, United States, 90033
Contact: Site Public Contact 323-865-0451
Principal Investigator: Kevin R. Kelly
USC / Norris Comprehensive Cancer Center
Recruiting
Los Angeles, California, United States, 90033
Contact: Site Public Contact 323-865-0451
Principal Investigator: Kevin R. Kelly
Keck Medical Center of USC Pasadena
Recruiting
Pasadena, California, United States, 91105
Contact: Site Public Contact 323-865-0451
Principal Investigator: Kevin R. Kelly
University of California Davis Comprehensive Cancer Center
Recruiting
Sacramento, California, United States, 95817
Contact: Site Public Contact 916-734-3089
Principal Investigator: Brian A. Jonas
United States, Kentucky
University of Kentucky/Markey Cancer Center
Recruiting
Lexington, Kentucky, United States, 40536
Contact: Site Public Contact 859-257-3379
Principal Investigator: Reshma Ramlal
United States, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center
Recruiting
Baltimore, Maryland, United States, 21287
Contact: Site Public Contact 410-955-8804 jhcccro@jhmi.edu
Principal Investigator: Jonathan A. Webster
United States, Massachusetts
Massachusetts General Hospital Cancer Center
Recruiting
Boston, Massachusetts, United States, 02114
Contact: Site Public Contact 877-726-5130
Principal Investigator: Myrna R. Nahas
Brigham and Women's Hospital
Recruiting
Boston, Massachusetts, United States, 02115
Contact: Site Public Contact 888-823-5923 ctsucontact@westat.com
Principal Investigator: Myrna R. Nahas
Beth Israel Deaconess Medical Center
Recruiting
Boston, Massachusetts, United States, 02215
Contact: Site Public Contact 617-667-9925
Principal Investigator: Myrna R. Nahas
Dana-Farber Cancer Institute
Recruiting
Boston, Massachusetts, United States, 02215
Contact: Site Public Contact 877-442-3324
Principal Investigator: Myrna R. Nahas
United States, Ohio
Ohio State University Comprehensive Cancer Center
Active, not recruiting
Columbus, Ohio, United States, 43210 收起 <<
United States, Illinois
... 展开 >>
University of Chicago
Withdrawn
Chicago, Illinois, United States, 60637
United States, Iowa
University of Iowa
Not yet recruiting
Iowa City, Iowa, United States, 52242
Contact: Carlos Vigil, M.D. carlos-vigil@uiowa.edu
Principal Investigator: Carlos Vigil, M.D.
United States, Massachusetts
Massachusetts General Hospital
Withdrawn
Boston, Massachusetts, United States, 02114
Dana-Farber Cancer Institute
Withdrawn
Boston, Massachusetts, United States, 02215
United States, Missouri
Washington University School of Medicine
Recruiting
Saint Louis, Missouri, United States, 63110
Contact: John Welch, M.D., Ph.D. 314-362-2626 jwelch@wustl.edu
Principal Investigator: John Welch, M.D., Ph.D.
United States, Texas
The University of Texas MD Anderson Cancer Center
Withdrawn
Houston, Texas, United States, 77030
United States, Washington
Fred Hutchinson Cancer Research Center
Not yet recruiting
Seattle, Washington, United States, 98109
Contact: Elihu Estey, M.D. 206-288-7176 eestey@u.washington.edu
Principal Investigator: Elihu Estey, M.D. 收起 <<
Castration Levels of Testoster... 展开 >>one
Castration-Resistant Prostate Carcinoma
Metastatic Prostate Carcinoma in the Soft Tissue
Prostate Carcinoma Metastatic in the Bone
PSA Level Greater Than or Equal to Two
PSA Progression
Stage IV Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8 收起 <<
Phase 1
Phase 2
Not yet recruiting
August 31, 2020
United States, New York
... 展开 >>
Roswell Park Cancer Institute
Not yet recruiting
Buffalo, New York, United States, 14263
Contact: Gurkamal S. Chatta 716-845-3117 Gurkamal.Chatta@roswellpark.org
Principal Investigator: Gurkamal S. Chatta 收起 <<
China, Beijing
... 展开 >> Biotherapeutic Department of Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100853
Contact: Weidong Han, Doctor +86-10-66937463 hanwdrsw@sina.com
Contact: Qingming Yang, Doctor +86-10-55499341 yangqm@medmail.com.cn
Principal Investigator: Yang Liu, Doctor
Principal Investigator: Chunmeng Wang, Master
Principal Investigator: Wenying Zhang, Master
Principal Investigator: Meixia Chen, Doctor
Principal Investigator: Weidong Han, Doctor
Principal Investigator: Qingming Yang, Doctor
Principal Investigator: Qian Mei, Doctor
Principal Investigator: Jing Nie, Doctor
Sub-Investigator: Yan Zhang, Doctor
Sub-Investigator: Kaichao Feng, Doctor
Sub-Investigator: Jingdan Qiu, Doctor
Sub-Investigator: Hejin Jia, Doctor
Sub-Investigator: Xiang Li, Master
Sub-Investigator: Liang Dong, Master
Sub-Investigator: Lu Shi, Master 收起 <<
United States, Maryland
... 展开 >>
University of Maryland Greenebaum Comprehensive Cancer Center
Recruiting
Baltimore, Maryland, United States, 21201
Contact: Sunita Philip, MPH, CCRP 410-328-8199 sphilip1@umm.edu
Contact: Gary Saum 410-328-1180 gary.saum@umm.edu
Principal Investigator: Maria Baer, MD 收起 <<
France
... 展开 >> CHU de Bicêtre
Le Kremlin-Bicêtre, Ile de France, France, 94275
CHU d'Amiens
Amiens, France, 80054
CH Angers
Angers, France, 49 000
Hôpital Avignon
Avignon, France, 84000
Hopital de la Cote Basque
Bayonne, France, 64100
Hôpital Avicenne
Bobigny, France, 93009
CHU Haut-Lévèque
Bordeaux, France, 33604
Hôpital Boulogne Sur Mer
Boulogne Sur Mer, France, 62321
Hopital d'Instruction des Armées Percy
Clamart, France, 92140
CHU de
Clermont Ferrand, France, 63058
Centre Hospitalier Sud-Francilien
Corbeil-Essonnes, France, 91106
Hopital Henri Mondor
Creteil, France, 94000
CHU de Dijon
Dijon, France, 21034
Hôpital Versailles
Le Chesnay, France, 78157
Centre Hospitalier du Mans
Le Mans cedex, France, 72037
Institut Paoli Calmettes
Marseille, France, 13009
CHU de nantes
Nantes, France, 44093
Hôpital Archet1
Nice, France, 06202
CHU Caremeau
Nimes, France, 30029
CHR La Source orléans
Orléans, France, 45067
Hôpital Saint-Antoine.
Paris-Cedex 12, France, 75571
Hopital Cochin
Paris, France, 75014
Hopital Necker
Paris, France, 75015
Hopital Hotel Dieu
Paris, France, 75181
Hoiptal St Louis
Paris, France, 75475
Centre Hospitalier Joffre
Perpignan, France, 66046
CHU de Reims
Reims, France, 51092
Centre Henri Becquerel
Rouen, France, 76038
Hematology Dpt, Hopital Purpan
Toulouse, France, 40031
CHU Bretoneau
Tours, France, 37044
Institut gustave Roussy
Villejuif, France, 94805 收起 <<
United States, Missouri
... 展开 >>
Washington University of St. Louis
Saint Louis, Missouri, United States, 63110
United States, New York
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029
Columbia University Medical Center
New York, New York, United States, 10032
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065
United States, North Carolina
Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, United States, 27157
United States, Ohio
Cleveland Clinic Taussig Cancer Center Institute
Cleveland, Ohio, United States, 44195
United States, Pennsylvania
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104 收起 <<
United States, Ohio
... 展开 >>
University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44195 收起 <<
United States, Pennsylvania
... 展开 >>
Penn State Cancer Institute
Recruiting
Hershey, Pennsylvania, United States, 17033
Contact: Clinical Research Nurse 717-531-7309 hzheng@pennstatehealth.psu.edu
Contact: Michelle Knapp, RN 717-531-0003 mknapp1@pennstatehealth.psu.edu
Principal Investigator: Hong Zheng, MD 收起 <<
United States, California
... 展开 >>
City of Hope Comprehensive Cancer Center
Recruiting
Duarte, California, United States, 91010
Contact: Site Public Contact 800-826-4673 becomingapatient@coh.org
Principal Investigator: Samer K. Khaled
University of California Davis Comprehensive Cancer Center
Recruiting
Sacramento, California, United States, 95817
Contact: Site Public Contact 916-734-3089
Principal Investigator: Brian A. Jonas
United States, Florida
Moffitt Cancer Center
Active, not recruiting
Tampa, Florida, United States, 33612
United States, Massachusetts
Massachusetts General Hospital Cancer Center
Recruiting
Boston, Massachusetts, United States, 02114
Contact: Site Public Contact 877-726-5130
Principal Investigator: Jacqueline S. Garcia
Brigham and Women's Hospital
Recruiting
Boston, Massachusetts, United States, 02115
Contact: Site Public Contact 888-823-5923 ctsucontact@westat.com
Principal Investigator: Jacqueline S. Garcia
Beth Israel Deaconess Medical Center
Recruiting
Boston, Massachusetts, United States, 02215
Contact: Site Public Contact 617-667-9925
Principal Investigator: Jacqueline S. Garcia
Dana-Farber Cancer Institute
Recruiting
Boston, Massachusetts, United States, 02215
Contact: Site Public Contact 877-442-3324
Principal Investigator: Jacqueline S. Garcia
United States, Ohio
Case Western Reserve University
Recruiting
Cleveland, Ohio, United States, 44106
Contact: Site Public Contact 800-641-2422 CTUReferral@UHhospitals.org
Principal Investigator: Benjamin K. Tomlinson
United States, Virginia
University of Virginia Cancer Center
Recruiting
Charlottesville, Virginia, United States, 22908
Contact: Site Public Contact 434-243-6303 PAS9E@virginia.edu
Principal Investigator: Michael K. Keng 收起 <<
United States, Massachusetts
... 展开 >>
Novartis Investigative Site
Recruiting
Boston, Massachusetts, United States, 02114
Contact: Meghan Burke 617-726-5131 Mburke19@partners.org
Principal Investigator: Andrew M. Brunner
United States, Oregon
Novartis Investigative Site
Recruiting
Portland, Oregon, United States, 97239
United States, Texas
Novartis Investigative Site
Recruiting
Houston, Texas, United States, 77030
Australia, Victoria
Novartis Investigative Site
Recruiting
Melbourne, Victoria, Australia, 3004
Finland
Novartis Investigative Site
Recruiting
Helsinki, Finland, FIN-00290
France
Novartis Investigative Site
Recruiting
Marseille, France, 13273
Germany
Novartis Investigative Site
Recruiting
Jena, Germany, 07740
Netherlands
Novartis Investigative Site
Recruiting
Amsterdam, Netherlands, 1081 HV
Spain
Novartis Investigative Site
Recruiting
Barcelona, Catalunya, Spain, 08036
United Kingdom
Novartis Investigative Site
Recruiting
Cardiff, United Kingdom, CF4 4XN 收起 <<
United States, Iowa
... 展开 >>
University of Iowa Hospitals and Clinics
Recruiting
Iowa City, Iowa, United States, 52242
Contact: Varun Monga, MD 319-384-9497 varun-monga@uiowa.edu 收起 <<
Belgium
... 展开 >> University of Liège
Liège, Belgium
Netherlands
University Medical Center Groningen (UMCG)
Groningen, Netherlands
Radboud university medical center
Nijmegen, Netherlands, 6500 HB 收起 <<
Other Diseases of Blood and Bl... 展开 >>ood-forming Organs
Acute Myeloid Leukemia
Myelodysplastic Syndrome 收起 <<
Phase 2
Recruiting
December 2020
United States, Texas
... 展开 >>
University of Texas MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact mkonople@mdanderson.org 收起 <<
China, Shandong
... 展开 >>
Qilu hospital, Shandong University
Recruiting
Jinan, Shandong, China, 250012
Contact: Ming Hou houming@medmail.com.cn
Principal Investigator: Ming Hou
Shandong University Qilu Hospital
Recruiting
Jinan, Shandong, China, 250012
Contact: Ming Lv
Principal Investigator: Ming Hou, Dr 收起 <<
Childhood Solid Tumor
... 展开 >> Childhood Lymphoma
Relapsed Cancer
Refractory Cancer
Adult Solid Tumor
Adult Lymphoma 收起 <<
Early Phase 1
Recruiting
May 12, 2022
United States, Ohio
... 展开 >>
Cincinnati Children's Hospital Medical Center
Recruiting
Cincinnati, Ohio, United States, 45229
Contact: Laura Fossett 513-636-2799 cancer@cchmc.org 收起 <<
United States, Arizona
... 展开 >>
Banner MD Anderson Cancer Center
Recruiting
Gilbert, Arizona, United States
United States, Connecticut
Yale Cancer Center
Recruiting
New Haven, Connecticut, United States
United States, Florida
Mayo Clinic
Recruiting
Jacksonville, Florida, United States
United States, Illinois
Loyola University Medical Center
Recruiting
Maywood, Illinois, United States
United States, Kansas
The University of Kansas Cancer Center
Recruiting
Westwood, Kansas, United States
United States, Minnesota
Mayo Clinic
Recruiting
Rochester, Minnesota, United States
United States, Missouri
Washington University School of Medicine
Recruiting
Saint Louis, Missouri, United States
United States, Nebraska
University of Nebraska Medical Center
Recruiting
Omaha, Nebraska, United States
United States, New York
Roswell Park Cancer Institute
Recruiting
Buffalo, New York, United States
Memorial Sloan Kettering Cancer Center
Recruiting
New York, New York, United States
Stony Brook University
Recruiting
Stony Brook, New York, United States
United States, Ohio
University Hospital of Cleveland Seidman Cancer Center
Recruiting
Cleveland, Ohio, United States
The Ohio State University Comprehensive Cancer Center
Recruiting
Columbus, Ohio, United States
United States, Texas
Baylor Charles A. Sammons Cancer Center
Recruiting
Dallas, Texas, United States
MD Anderson Cancer Center
Recruiting
Houston, Texas, United States
United States, Washington
Fred Hutchinson Cancer Research Center
Recruiting
Seattle, Washington, United States
United States, Wisconsin
Medical College of Wisconsin
Recruiting
Milwaukee, Wisconsin, United States
Canada, Ontario
University of Ottawa
Recruiting
Ottawa, Ontario, Canada 收起 <<
China, Guangdong
... 展开 >>
Department of Hematology,Nanfang Hospital, Southern Medical University
Recruiting
Guangzhou, Guangdong, China, 510515
Contact: Hua Jin +86-020-61641613 499509173@qq.com 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, California
City of Hope National Medical Center
Duarte, California, United States, 91010-3000
United States, Florida
H. Lee Moffitt Cancer Center & Research Institute
Tampa, Florida, United States, 33612
United States, Georgia
Winship Cancer Institute / Emory University School of Medicine
Atlanta, Georgia, United States, 30322
United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
United States, Michigan
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States, 48109
United States, New Jersey
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
United States, New York
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10021
United States, Ohio
Cleveland Clinic, The
Cleveland, Ohio, United States, 44195
United States, Texas
Charles A. Sammons Cancer Center / Baylor University Medical Center
Dallas, Texas, United States, 75246
MD Anderson Cancer Center / University of Texas
Houston, Texas, United States, 77030-4095
United States, Utah
University of Utah
Salt Lake City, Utah, United States, 84112
United States, Washington
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States, 98109-1024 收起 <<
United States, Florida
... 展开 >>
Moffitt Cancer Center
Recruiting
Tampa, Florida, United States, 33612
Contact: Rami Komrokji, MD
United States, Maryland
John Hopkins
Recruiting
Baltimore, Maryland, United States, 21218
Contact: Amy DeZern, MD
United States, Massachusetts
Dana Farber
Recruiting
Boston, Massachusetts, United States, 02215
Contact: David Steensma, MD
United States, New York
Weill Cornell Medicin
Recruiting
New York, New York, United States, 10065
Contact: Gail Roboz, MD
United States, Ohio
Cleveland Clinic
Recruiting
Cleveland, Ohio, United States, 44195
Contact: Mikkael Sekeres, MD
United States, Texas
University of Texas MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: Clinical Research Operations cdinardo@mdanderson.org 收起 <<
United States, California
... 展开 >>
Children's Hospital Oakland
Oakland, California, United States, 94609
United States, Massachusetts
Children's Hospital
Boston, Massachusetts, United States, 02115
United States, New York
Weill Medical College of Cornell University
New York, New York, United States, 10021
United States, Pennsylvania
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Canada, Ontario
Toronto General Hospital
Toronto, Ontario, Canada, M5G 2C4 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, California
Stanford University
Stanford, California, United States, 94305-5826
United States, Colorado
Hospital Corporation of America-HealthOne, LLC
Denver, Colorado, United States, 80218
United States, Florida
Mayo Clinic - Jacksonville, FL
Jacksonville, Florida, United States, 32224
University of Miami School of Medicine
Miami, Florida, United States, 33136
United States, North Carolina
UNC-Chapel Hill School of Medicine
Chapel Hill, North Carolina, United States, 27599
United States, Tennessee
Sarah Cannon Research Institute
Nashville, Tennessee, United States, 37203
United States, Texas
Methodist Hospital
San Antonio, Texas, United States, 78229 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic Arizona
Recruiting
Phoenix, Arizona, United States, 85054
Principal Investigator: Lisa Sproat, MD
United States, California
UCLA Ronald Reagan Medical Center
Recruiting
Los Angeles, California, United States, 90095
Principal Investigator: Gary Schiller, MD
University of California, San Francisco
Recruiting
San Francisco, California, United States, 94143
Principal Investigator: Gabriel Mannis, MD
United States, Colorado
University of Colorado
Recruiting
Denver, Colorado, United States, 80203
Principal Investigator: Dan Pollyea, MD
United States, Florida
Mayo Clinic Florida
Recruiting
Jacksonville, Florida, United States, 32224
Principal Investigator: James Foran, MD
United States, Georgia
Emory University
Recruiting
Atlanta, Georgia, United States, 30308
Principal Investigator: William Blum, MD
United States, Illinois
University of Chicago
Recruiting
Chicago, Illinois, United States, 60637
Principal Investigator: Wendy Stock, MD
United States, Maryland
University of Maryland Medical Center
Recruiting
Baltimore, Maryland, United States, 21201
Principal Investigator: Maria Baer, MD
United States, New York
Memorial Sloan Kettering Cancer Center
Recruiting
New York, New York, United States, 10065
Principal Investigator: Eytan M Stein, MD
United States, Ohio
Ohio State University
Recruiting
Columbus, Ohio, United States, 43210
Principal Investigator: John C Byrd, MD
Principal Investigator: Alice Mims, MD
Principal Investigator: Alison R Walker, MD, MPH
United States, Oregon
Oregon Health & Science University
Recruiting
Portland, Oregon, United States, 97239
Principal Investigator: Uma Borate, MD
United States, Texas
University of Texas Southwestern
Recruiting
Dallas, Texas, United States, 75390
Principal Investigator: Prapti Patel, MD
United States, Utah
Huntsman Cancer Institute, University of Utah
Recruiting
Salt Lake City, Utah, United States, 84112
Principal Investigator: Michael Deininger, MD, PhD 收起 <<
United States, Florida
... 展开 >>
Research Site
Tampa, Florida, United States, 33613
United States, New York
Research Site
Bronx, New York, United States, 10467
Research Site
New York, New York, United States, 10021
United States, Texas
Research Site
Houston, Texas, United States, 77030 收起 <<
Terminated(Study terminated du... 展开 >>e to slow enrollment.) 收起 <<
-
France
... 展开 >> Hopital Avicenne/University
Paris, France, 93009
Germany
St. Johannes-Hospital Duisburg
Duisburg, Germany, 47166
Medizinische Hochschule Hannover
Hannover, Germany, 30625
Netherlands
UMC St Radboud Centraal
Nijmegen, Netherlands, 6525 GA
United Kingdom
Royal Bournemouth Hospital
Bournemouth, England, United Kingdom, BH7 7DW
St. James Hospital
Leeds, England, United Kingdom, LS9 7TF
King's College Hospital
London, England, United Kingdom, SE5 9RS 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic
Scottsdale, Arizona, United States, 85259
United States, California
University of Southern California
Los Angeles, California, United States, 90033
United States, Connecticut
Yale University
New Haven, Connecticut, United States, 06520
United States, Florida
Florida Cancer Specialists - South
Fort Myers, Florida, United States, 33916
Florida Cancer Specialists - North
Saint Petersburg, Florida, United States, 33705
United States, Illinois
University of Chicago Cancer Center
Chicago, Illinois, United States, 60637
United States, New York
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Cornell University
New York, New York, United States, 10021
Columbia University Medical Center
New York, New York, United States, 10032
United States, North Carolina
Duke University
Durham, North Carolina, United States, 27705
United States, Ohio
Ohio State University
Columbus, Ohio, United States, 43210
United States, Pennsylvania
Temple University
Philadelphia, Pennsylvania, United States, 19111
United States, Tennessee
Sarah Cannon Research Institute
Nashville, Tennessee, United States, 37203
Tennessee Oncology
Nashville, Tennessee, United States, 37203
United States, Texas
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Canada, Ontario
Princess Margaret Hospital
Toronto, Ontario, Canada, M5G 2M9 收起 <<
United States, Arizona
... 展开 >>
The University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States, 85719
Banner-University Medical Center Tucson
Tucson, Arizona, United States, 85724
United States, Illinois
The University of Chicago Medical Center
Chicago, Illinois, United States, 60637
United States, North Carolina
Wake Forest Baptist Health
Winston-Salem, North Carolina, United States, 27157 收起 <<
France
... 展开 >> Service de rythmologie - GH Est-Hôpital Louis Pradel - CHU de Lyon HCL
Not yet recruiting
Bron, France, 69229
Contact: Philippe CHEVALIER, MD 04 72 35 76 89 ext +33 philippe.chavalier@chu-lyon.fr
Contact: Camille VALLA 04 27 85 62 69 ext +33 camille.valla@chu-lyon.fr
Principal Investigator: Philippe CHEVALIER, MD 收起 <<
China, Guangdong
... 展开 >>
Department of Hematology,Nanfang Hospital, Southern Medical University
Recruiting
Guangzhou, Guangdong, China, 510515
Contact: Li Xuan +86-020-61641613 356135708@qq.com
Principal Investigator: Qifa Liu 收起 <<
United States, New York
... 展开 >>
Roswell Park Cancer Institute
Not yet recruiting
Buffalo, New York, United States, 14263
Contact: Kunle Odunsi 716-845-8376 kunle.odunsi@roswellpark.org
Principal Investigator: Kunle Odunsi 收起 <<
Acute Myeloid Leukemia With In... 展开 >>v(16)(p13.1q22); CBFB-MYH11
Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1
de Novo Myelodysplastic Syndrome
High Risk Myelodysplastic Syndrome
Inv(16)
Myelodysplastic Syndrome With Excess Blasts
t(16;16)
t(8;21)
Untreated Adult Acute Myeloid Leukemia 收起 <<
Phase 2
Recruiting
April 30, 2020
United States, Texas
... 展开 >>
M D Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: Gautam Borthakur 713-563-1586
Principal Investigator: Gautam Borthakur 收起 <<
United States, California
... 展开 >>
City of Hope Comprehensive Cancer Center
Recruiting
Duarte, California, United States, 91010
Contact: Weili Sun, MD,PhD 800-826-4673 weilisun@coh.org
Principal Investigator: Weili Sun, MD,PhD
Children's Hospital of Central California
Recruiting
Madera, California, United States, 93636
Contact: Faisal Razzaqi, MD 866-353-5437 frazzaqi@valleychildrens.org
Principal Investigator: Faisal Razzaqi, MD
Children's Hospital of Orange County
Recruiting
Orange, California, United States, 92968
Contact: Jamie Frediani, MD 714-509-4348 jfrediani@choc.org
Principal Investigator: Jamie Frediani, MD
Lucile Packard Children's Hospital Stanford University
Recruiting
Palo Alto, California, United States, 94304
Contact: Norman J. Lacayo, MD 650-497-8953 lacayon@stanford.edu
Principal Investigator: Norman J. Lacayo, MD
Rady Children's Hospital and Health Center
Recruiting
San Diego, California, United States, 92123
Contact: Deborah Schiff, MD 858-966-5983 dschiff@chsd.org
Principal Investigator: Deborah Schiff, MD
United States, Tennessee
St. Jude Children's Research Hospital
Recruiting
Memphis, Tennessee, United States, 38105
Contact: Tanja A. Gruber, MD, PhD 866-278-5833 tanja.gruber@stjude.org
Contact: Referral Office 866-278-5833 referralinfo@stjude.org
Principal Investigator: Tanja A. Gruber, MD, PhD
United States, Texas
Cook Children's Medical Center
Recruiting
Fort Worth, Texas, United States, 76104
Contact: Kenneth M. Heym, MD 682-885-4007 kenneth.heym@cookchildrens.org
Principal Investigator: Kenneth M. Heym, MD 收起 <<
United States, California
... 展开 >>
UCLA
Los Angeles, California, United States
United States, Illinois
University of Chicago
Chicago, Illinois, United States
Loyola University Medical Center
Maywood, Illinois, United States
United States, Indiana
Indiana University
Indianapolis, Indiana, United States
United States, Kansas
University of Kansas Medical Center Research Institute, Inc
Fairway, Kansas, United States
United States, Massachusetts
Dana Farber Cancer Institute
Boston, Massachusetts, United States
United States, Michigan
Henry Ford Health System
Detroit, Michigan, United States
Karmanos Cancer Institute
Detroit, Michigan, United States
United States, New York
Weill Cornell Medical College - New York - Presbyterian Hospital
New York, New York, United States
United States, North Carolina
Duke Cancer Center
Durham, North Carolina, United States
United States, Ohio
University Hospitals Case Medical Center
Cleveland, Ohio, United States
Ohio State University
Columbus, Ohio, United States
United States, Oregon
Oregon Health & Science University
Portland, Oregon, United States, 97239
United States, South Carolina
Saint Francis Cancer Center
Greenville, South Carolina, United States
Canada, Ontario
Princess Margaret
Toronto, Ontario, Canada
Canada, Quebec
Jewish General Hospital
Montreal, Quebec, Canada
Germany
Universitätsklinikum Frankfurt Medizinische Klinik II
Frankfurt, Germany, 60590 收起 <<
China
... 展开 >> Beijing Friendship Hospital
Not yet recruiting
Beijing, China
Fujian Medical University Union Hospital
Not yet recruiting
Fuzhou, China
The People's Hospital of Guangxi Zhuang Autonomous Region
Not yet recruiting
Nanning, China
Shanghai Tong Ren hospital
Recruiting
Shanghai, China
Contact: Ligen Liu 18017337037 llg3532@shtrhospital.com
The center hospital of Shanghai Fengxian District
Not yet recruiting
Shanghai, China
First Affiliated Hospital of Zhengzhou University.
Not yet recruiting
Zhengzhou, China 收起 <<
United Kingdom
... 展开 >> UHW
Recruiting
Cardiff, United Kingdom, CF14 4XN
Principal Investigator: Steve Knapper
Nottingham University Hospital
Recruiting
Nottingham, United Kingdom
Contact: Nigel Russell, MD 收起 <<
France
... 展开 >> Centre hospitalier de la côte Basque
Bayonne, France, 64100
Hôpital Avicenne
Bobigny, France, 93009
CHU de Haut-Lévèque
Bordeaux Pessac, France, 33604
Centre henri Mondor
Creteil, France, 94010
CHU de Grenoble
Grenoble, France, 38043
CHU de Limoges
Limoges, France, 87042
Institut paoli calmettes
Marseille, France, 13273
centre hospitalier de Meaux
Meaux, France, 77100
CHU de nantes
Nantes, France, 44093
Centre Antoine Lacassagne
Nice, France, 06189
Hôpital L'archet 1, Nice
Nice, France, 06202 cedex 3
Hôpital Saint Louis
Paris, France, 75010
Hôpital Saint Antoine
Paris, France, 75012
Hôpital Saint-Louis
Paris, France, 75475 cedex 10
Hôpital Cochin
Paris, France, 75679 cedex14
Centre henri Becquerel
Rouen, France, 76038
Hôpital Bretonneau de Tours
Tours, France, 37000 收起 <<
China
... 展开 >> China PLA General Hospital
Recruiting
Beijing, China, 100039
Contact: Li Yu, M.D Ph.D 010-66937644 chunhuiliyu@yahoo.com
Principal Investigator: Li-Xin Yu 收起 <<
United States, Ohio
... 展开 >>
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
Columbus, Ohio, United States, 43210 收起 <<
United States, Colorado
... 展开 >>
University of Colorado, Anschutz Cancer Pavilion
Recruiting
Aurora, Colorado, United States, 80045
Contact: Daniel Pollyea, MD
Contact: Derek Schatz, BS, CCRP 720-848-0628 derek.schatz@ucdenver.edu
United States, Florida
BRCR Medical Center Inc.
Recruiting
Plantation, Florida, United States, 33324
Contact: Harshad Amin, MD
Contact: Mariaclaudia Reyes 561-447-0614 mreyes@brcrglobal.com
United States, Kansas
University of Kansas Clinical Research Center
Recruiting
Westwood, Kansas, United States, 66205
Contact: Abdulraheem Yacoub, MD
United States, Michigan
Karmanos Cancer Institute
Recruiting
Detroit, Michigan, United States, 48201
Contact: Jay Yang, MD 313-576-8952 yangj@karmanos.org
Contact: Christiane Houde, BS 313-576-9381 houdec@karmanos.org 收起 <<
Chronic Myelomonocytic Leukemi... 展开 >>a
de Novo Myelodysplastic Syndrome
Myelodysplastic Syndrome
Secondary Myelodysplastic Syndrome 收起 <<
Phase 2
Recruiting
-
United States, Arizona
... 展开 >>
Mayo Clinic in Arizona
Recruiting
Scottsdale, Arizona, United States, 85259
Contact: Mayo Clinic Clinical Trials Office 855-776-0015 cancerclinicaltrials@mayo.edu
Principal Investigator: Nandita Khera
United States, Ohio
Cleveland Clinic Foundation
Recruiting
Cleveland, Ohio, United States, 44195
Contact: Aaron T. Gerds 216-444-6833 gerdsa@ccf.org
Principal Investigator: Aaron T. Gerds
United States, Washington
Fred Hutch/University of Washington Cancer Consortium
Recruiting
Seattle, Washington, United States, 98109
Contact: Bart L. Scott 206-667-1990 bscott@fhcrc.org
Principal Investigator: Bart L. Scott
Kaiser Permanente Washington
Terminated
Seattle, Washington, United States, 98112 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 收起 <<
United States, Texas
... 展开 >>
University of Texas MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact tkadia@mdanderson.org 收起 <<
United States, California
... 展开 >>
USC / Norris Comprehensive Cancer Center
Not yet recruiting
Los Angeles, California, United States, 90033
Contact: Mojtaba Akhtari mojtaba.akhtari@med.usc.edu
Principal Investigator: Mojtaba Akhtari
United States, Nebraska
University of Nebraska Medical Center
Recruiting
Omaha, Nebraska, United States, 68198
Contact: Vijaya R. Bhatt 402-559-8008 vijaya.bhatt@unmc.edu
Principal Investigator: Vijaya R. Bhatt 收起 <<
France
... 展开 >> CH Angers
Angers, France, 49 000
CH Avignon
Avignon, France, 84000
Centre Hospitalier de La Cote Basque
Bayonne, France, 64100
Hôpital Avicenne
Bobigny, France, 93 000
CHU Clémenceau
Caen, France, 14033
CHU Henri Mondor
Créteil, France, 94010
CHU de Grenoble
Grenoble, France, 38043
Centre Hospitalier du Mans
Le Mans, France, 72000
CHRU Limoges
Limoges, France, 87046
CH Lyon Sud
Lyon, France, 69495
Hôpital Paoli Calmettes
Marseille, France, 13273
Centre Hospitalier de Meaux
Meaux, France, 77100
Clinique Beausoleil (Montpellier)
Montpellier, France, 34000
CHU de nantes
Nantes, France, 44093
Centre Catherine de Sienne (Nantes)
Nantes, France, 44277
CHU de Nice - Hopital de l'Archet 1
Nice, France, 06 202
CHR Orléans
Orléans, France, 45000
Hopital St Louis T4
Paris, France, 75475
Centre Hospitalier Joffre
Perpignan, France, 66046
CHU de Haut-Lévèque
Pessac, France, 33604
CHU de Poitiers
Poitiers, France, 86000
Centre Hospitalier de la région d'Annecy
Pringy, France, 74374
Centre Henri Becquerel
Rouen, France, 76038
Chu Purpan
Toulouse, France, 31059
Hopital Purpan Service d'Hématologie Clinique
Toulouse, France
CHU Bretonneau
Tours, France, 37044
CHU Brabois
Vandœuvre-lès-Nancy, France, 54511 收起 <<
United States, Alabama
... 展开 >>
Southern Cancer Center
Mobile, Alabama, United States, 36608
United States, California
City of Hope
Duarte, California, United States, 91010
USC Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033
Sutter Medical Group
Sacramento, California, United States, 95816
United States, Colorado
Colorado Blood Cancer Institute
Denver, Colorado, United States, 80218
United States, Connecticut
Yale School of Medicine
New Haven, Connecticut, United States, 06520
United States, Florida
Florida Cancer Specialist South
Fort Myers, Florida, United States, 33916
Florida Cancer Specialist North
St Petersburg, Florida, United States, 33705
United States, Illinois
Northwestern University
Chicago, Illinois, United States, 60601
United States, Kansas
University of Kansas Cancer Center
Westwood, Kansas, United States, 66205
United States, Kentucky
University of Kentucky
Lexington, Kentucky, United States, 40536
United States, New Jersey
John Theurer Cancer Center
Hackensak, New Jersey, United States, 07601
United States, Ohio
Oncology Hematology Care
Cincinati, Ohio, United States, 45242
Cleveland Clinic
Cleveland, Ohio, United States, 44195
United States, Oklahoma
University of Oklahoma Health Science Center
Oklahoma City, Oklahoma, United States, 73104
United States, Tennessee
Tennessee Oncology-Chattanooga
Chattanooga, Tennessee, United States, 37404
Tennessee Oncology
Nashville, Tennessee, United States, 37203
United States, Texas
Baylor University Medical Center
Dallas, Texas, United States, 75246
University of Texas Southwestern
Dallas, Texas, United States, 75390
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Cancer Care Centers of South Texas
San Antonio, Texas, United States, 78229 收起 <<
United States, Minnesota
... 展开 >>
Children's Hospitals and Clinics of Minnesota
Minneapolis, Minnesota, United States, 55404
United States, Wisconsin
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States, 53226 收起 <<
China, Guangdong
... 展开 >>
Department of Hematology,Nanfang Hospital, Southern Medical University
Recruiting
Guangzhou, Guangdong, China, 510515
Contact: Li Xuan +86-020-62787883 356135708@qq.com
Principal Investigator: Qifa Liu 收起 <<
China
... 展开 >> Chinese PLA General Hospital
Recruiting
Beijing, China, 100853
Contact: Li Yu, M.D. Ph.D. 86-010-55499003 chunhuiliyu@yahoo.com
Principal Investigator: Li Yu, M.D. Ph.D. 收起 <<
United States, California
... 展开 >>
Scripps Health
Recruiting
San Diego, California, United States, 92103
Contact: Marin Xavier, M.D.
Contact: Boyka S Petrov Petrov.Boyka@scrippshealth.org
United States, Georgia
Georgia Cancer Center-Augusta University
Recruiting
Augusta, Georgia, United States, 30912
Contact: Jeremy M Pantin, M.D.
Contact: Christine Sanchez csanchez@augusta.edu
United States, Nevada
Comprehensive Cancer Centers of Nevada
Recruiting
Las Vegas, Nevada, United States, 89169
Contact: Khin Win, MBBS, CCRC khin.win@usoncology.com
Contact: Tiffany Gordon tiffany.gordon@usoncology.com
Principal Investigator: Edwin Kingsley, MD
United States, New Mexico
New Mexico Cancer Care Alliance
Recruiting
Albuquerque, New Mexico, United States, 87106
Contact: Kaylee Deutsch, MHA, CCRP kdeutsch@nmcca.org
Contact: April Encee, RN, OCN aencee@salud.unm.edu
Principal Investigator: Cecilia Arana-Yi, MD
United States, North Carolina
Duke Cancer Institute, Duke Univ Medical Center
Recruiting
Durham, North Carolina, United States, 27710
Contact: David Rizzieri, M.D.
Contact: Rachel Stowe rachel.stowe@duke.edu
United States, Texas
University of Texas; M D Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: Jorge Cortes, M.D.
Contact: Jane A Autry JAAutry@mdanderson.org
United States, Wisconsin
ProHealth Care Inc
Not yet recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Dawn Minikel dawn.minikel@phci.org
Contact: Amelia Crouse amelia.crouse@phci.org
Principal Investigator: Timothy Wassenaar, MD
France
Necker Hospital- APHP
Recruiting
Paris, France, 75015
Contact: Olivier Hermine, MD, PhD 收起 <<
United States, Iowa
... 展开 >>
University of Iowa Hospitals and Clinics
Recruiting
Iowa City, Iowa, United States, 52242
Contact: Karen Parrott 319-353-6347 karen-parrott@uiowa.edu
Principal Investigator: Carlos E Vigil, MD
United States, Ohio
James Cancer Hospital & Solove Research Institute
Recruiting
Columbus, Ohio, United States, 43210
Contact: Molly Vittorio 614-293-7940 molly.vittorio@osumc.edu
Principal Investigator: William Blum, Professor
United States, Texas
MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: Cora Cheung 713-792-3461 cmcheung@mdanderson.org
Principal Investigator: Jorge Cortes, Professor
Germany
Universitätsklinikum Frankfurt, Medizinische Klinik II
Recruiting
Frankfurt, Germany, 60596
Contact: Laura Hefermehl +49 69 6301 86708 Laura.Hefermehl@kgu.de
Principal Investigator: Jörg Chromik, Dr
University Medical Center Hamburg-Eppendorf Martinistrasse
Recruiting
Hamburg, Germany, 20246
Contact: Sonja T Loges, MD, PhD +49 407-410-51969 s.loges@uke.de
Principal Investigator: Sonja Loges, MD, PhD
Medizinische Hochschule Hannover
Recruiting
Hannover, Germany, 30625
Contact: Gabriele Samson +49 (511) 532 9321 samson.gabriele@mh-hannover.de
Principal Investigator: Michael Heuser, Dr
Universitätsklinikum Ulm, Oberer Eselsberg, Zentrum für Innere Medizin III
Recruiting
Ulm, Germany, 89081
Contact: Manuela Wetzel +49 (0) 731 500 45709 manuela.wetzel@uniklinik-ulm.de
Principal Investigator: Peter Paschka, Dr
Norway
Haukeland University Hospital
Recruiting
Bergen, Norway, 5021
Contact: Marianne Emblem Lehmann +47 59972890/ 95975516 marianne.emblem.lehmann@helse-bergen.no
Principal Investigator: Bjørn Tore Gjertsen, Professor 收起 <<
United States, Pennsylvania
... 展开 >>
Temple BMT Program at Jeanes Hospital
Recruiting
Philadelphia, Pennsylvania, United States, 19111
Principal Investigator: Patricia Kropf, MD
Principal Investigator: Jean-Pierre Issa, MD
Sub-Investigator: Stefan Barta, MD
Sub-Investigator: Philip Pancari, MD
Sub-Investigator: Henry Fung, MD
United States, Texas
M.D. Anderson Cancer Center
Not yet recruiting
Houston, Texas, United States, 77030
Contact: Alexandra Thackrey, RN- BC 713-745-2238 AMThackrey@mdanderson.org
Principal Investigator: Hagop Kantarjian, MD 收起 <<
Advanced Esophageal Cancers
... 展开 >> Primary Small Cell Lung Cancers
Non-Small-Cell Lung Carcinoma
Pleural Mesotheliomas
Cancers of Non-thoracic Origin With Metastases to the Lungs or Pleura 收起 <<
Phase 1
Completed
-
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892 收起 <<
Carcinoma, Non-Small-Cell Lung... 展开 >>
Lung Cancer
Non-Small Cell Lung Cancer 收起 <<
Phase 1
Phase 2
Recruiting
December 31, 2020
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 收起 <<
United States, Texas
... 展开 >>
M D Anderson Cancer Center
Not yet recruiting
Houston, Texas, United States, 77030
Contact: Tapan M. Kadia 713-563-3534
Principal Investigator: Tapan M. Kadia 收起 <<
Chronic Myelomonocytic Leukemi... 展开 >>a
de Novo Myelodysplastic Syndromes
Myelodysplastic Syndromes
Refractory Anemia
Refractory Anemia With Excess Blasts
Refractory Anemia With Ringed Sideroblasts
Refractory Cytopenia With Multilineage Dysplasia
Thrombocytopenia 收起 <<
Phase 1
Phase 2
Completed
-
United States, Ohio
... 展开 >>
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44195 收起 <<
United States, California
... 展开 >>
USC / Norris Comprehensive Cancer Center
Recruiting
Los Angeles, California, United States, 90033
Contact: Ibrahim L. Syed 323-865-3928 Ibrahim.Syed@med.usc.edu
Principal Investigator: Casey L. O'Connell, MD 收起 <<
United States, Massachusetts
... 展开 >>
Dana-Farber Cancer Institute
Recruiting
Boston, Massachusetts, United States, 02115
Contact: Richard M. Stone, MD 617-632-2214 rstone@partners.org
Principal Investigator: Richard Stone, MD
Beth Israel Deaconess Medical Center
Recruiting
Boston, Massachusetts, United States, 02215
Contact: David Avigan, MD 617-667-9920 davigan@bidmc.harvard.edu
Principal Investigator: David Avigan, MD 收起 <<
United States, Massachusetts
... 展开 >>
Beth Israel Deaconess Medical Center
Recruiting
Boston, Massachusetts, United States, 02215
Contact: Emma Logan, BSN 617-667-5984 eklogan@bidmc.harvard.edu
Principal Investigator: Jacalyn Rosenblatt, MD
Dana Farber Cancer Institute
Not yet recruiting
Boston, Massachusetts, United States, 02215
Contact: Robert J Soiffer, MD Robert_soiffer@dfci.harvard.edu
Principal Investigator: Robert J Soiffer, MD 收起 <<
United States, Illinois
... 展开 >>
Rush University Medical Center
Chicago, Illinois, United States, 60612
United States, New York
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
United States, Texas
MD Anderson Cancer Center
Houston, Texas, United States, 77030-3387 收起 <<
United States, California
... 展开 >>
City of Hope Medical Center
Duarte, California, United States
Scripps Clinic
Escondido, California, United States
USC/Norris Cancer Center
Los Angeles, California, United States
United States, Minnesota
Metro-Minnesota CCOP
St. Louis Park, Minnesota, United States
United States, New York
New York Medical College
Valhalla, New York, United States
United States, South Carolina
Liberty Hematology/Oncology
Columbia, South Carolina, United States
United States, Texas
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Canada, Ontario
Princess Margaret Hospital
Toronto, Ontario, Canada 收起 <<
United States, California
... 展开 >>
Beckman Research Institute, City of Hope
Duarte, California, United States, 91010
USC/Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033-0800
Los Angeles County-University of Southern California Medical Center
Los Angeles, California, United States, 90033
University of California Davis Cancer Center
Sacramento, California, United States, 95817 收起 <<
United States, California
... 展开 >>
City of Hope Medical Center
Duarte, California, United States
Scripps Clinic
Escondido, California, United States
USC/Norris Cancer Center
Los Angeles, California, United States
United States, Minnesota
Metro-Minnesota CCOP
St. Louis Park, Minnesota, United States
United States, New York
New York Medical College
Valhalla, New York, United States
United States, South Carolina
Liberty Hematology/Oncology
Columbia, South Carolina, United States
United States, Texas
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Canada, Ontario
Princess Margaret Hospital
Toronto, Ontario, Canada 收起 <<
United States, California
... 展开 >>
City of Hope Medical Center
Duarte, California, United States
Scripps Clinic
Escondido, California, United States
USC/Norris Cancer Center
Los Angeles, California, United States
United States, Minnesota
Metro-Minnesota CCOP
St. Louis Park, Minnesota, United States
United States, New York
New York Medical College
Valhalla, New York, United States
United States, South Carolina
Liberty Hematology/Oncology
Columbia, South Carolina, United States
United States, Texas
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Canada, Ontario
Princess Margaret Hospital
Toronto, Ontario, Canada 收起 <<
Esophageal Cancer
... 展开 >> Lung Cancer
Malignant Mesothelioma
Metastatic Cancer 收起 <<
Phase 1
Completed
-
United States, Maryland
... 展开 >>
Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support
Bethesda, Maryland, United States, 20892-1182
Center for Cancer Research
Bethesda, Maryland, United States, 20892 收起 <<
Italy
... 展开 >> Medical Oncology and Immunotherapy Unit, University Hospital of Siena
Recruiting
Siena, Italy, 53100
Contact: Anna Maria Di Giacomo, PhD, MD +390577586305 a.m.digiacomo@ao-siena.toscana.it
Contact: Giovanni Amato, PhD +390577586326 dataman.immonco@ao-siena.toscana.it 收起 <<
United States, Pennsylvania
... 展开 >>
Abramson Cancer Center of the University of Pennsylvania
Not yet recruiting
Philadelphia, Pennsylvania, United States, 19104 收起 <<
United States, Washington
... 展开 >>
Fred Hutch/University of Washington Cancer Consortium
Recruiting
Seattle, Washington, United States, 98109
Contact: Pamela S. Becker 206-616-1589 pbecker@u.washington.edu
Principal Investigator: Pamela S. Becker 收起 <<
Suspended(Study enrollment on ... 展开 >>hold to evaluate safety and efficacy data.) 收起 <<
January 31, 2019
United States, California
... 展开 >>
City of Hope
Duarte, California, United States, 91010
United States, Connecticut
Yale University
New Haven, Connecticut, United States, 06511
United States, New York
The NewYork-Presbyterian Hospital Columbia University Medical Center
New York, New York, United States, 10032
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
United States, North Carolina
Levine Cancer Institute
Charlotte, North Carolina, United States, 28204
United States, Pennsylvania
Temple University Hospital
Philadelphia, Pennsylvania, United States, 19140
United States, Utah
Huntsman Cancer Institute
Salt Lake City, Utah, United States, 84112
United States, Wisconsin
The University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, United States, 53705 收起 <<
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