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Cyclic AMP/环磷腺苷 {[allProObj[0].p_purity_real_show]}

货号：A353547 同义名： 腺苷-3'，5'-环磷酸 / Cyclic adenosine monophosphate; Adenosine cyclic 3',5'-monophosphate

cAMP is cyclic adenosine monophosphate.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Cyclic AMP/环磷腺苷 化学结构 CAS号：60-92-4
Cyclic AMP/环磷腺苷 化学结构
CAS号：60-92-4
Cyclic AMP/环磷腺苷 3D分子结构
CAS号：60-92-4
Cyclic AMP/环磷腺苷 化学结构 CAS号：60-92-4
Cyclic AMP/环磷腺苷 3D分子结构 CAS号：60-92-4
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Cyclic AMP/环磷腺苷 纯度/质量文件 产品仅供科研

货号：A353547 标准纯度： {[allProObj[0].p_purity_real_show]}
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Cyclic AMP/环磷腺苷 生物活性

描述 cAMP (Cyclic adenosine monophosphate) is the first discovered second messenger, which plays pivotal roles in cell signaling, and regulates many physiological and pathological processes. cAMP can regulate the transcription of various target genes, mainly through protein kinase A (PKA) and its downstream effectors such as cAMP-responsive element binding protein (CREB). cAMP signaling may have both tumor-suppressive and tumor-promoting roles depending on the tumor types and context. cAMP-PKA signaling can regulate cancer cell growth, migration, invasion and metabolism[1]. The second messenger cyclic AMP (cAMP) is a major intracellular mediator of many hormones and neurotransmitters and regulates a myriad of cell functions, including synaptic plasticity in neurons[2]. cAMP critically modulates the development of neuronal connectivity. It is involved in a wide range of cellular processes that require independent regulation. The subcellular compartmentalization and temporal regulation of cAMP signals have recently been identified as important coding strategies leading to specificity[3].

Cyclic AMP/环磷腺苷 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00008008 Brain and Central Nervous Syst... 展开 >>em Tumors 收起 << Phase 2 Completed - United States, New Jersey ... 展开 >> St. Joseph's Hospital and Medical Center Paterson, New Jersey, United States, 07503 United States, New York Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center New York, New York, United States, 10032 收起 <<
NCT02620878 Type 1 Diabetes Not Applicable Completed - -
NCT01621776 Type 1 Diabetes Not Applicable Completed - United States, Florida ... 展开 >> Camp Winona DeLeon Springs, Florida, United States, 32130 收起 <<

Cyclic AMP/环磷腺苷 参考文献

[1]Zhang H, Kong Q, Wang J, Jiang Y, Hua H. Complex roles of cAMP-PKA-CREB signaling in cancer. Exp Hematol Oncol. 2020 Nov 24;9(1):32.

[2]Calebiro D, Maiellaro I. cAMP signaling microdomains and their observation by optical methods. Front Cell Neurosci. 2014 Oct 28;8:350.

[3]Averaimo S, Nicol X. Intermingled cAMP, cGMP and calcium spatiotemporal dynamics in developing neuronal circuits. Front Cell Neurosci. 2014 Nov 13;8:376.

Cyclic AMP/环磷腺苷 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.04mL

0.61mL

0.30mL

15.19mL

3.04mL

1.52mL

30.38mL

6.08mL

3.04mL

Cyclic AMP/环磷腺苷 技术信息

CAS号60-92-4
分子式C10H12N5O6P
分子量 329.21
SMILES Code NC1=NC=NC2=C1N=CN2[C@@H]3O[C@@](COP(O4)(O)=O)([H])[C@]4([H])[C@H]3O
MDL No. MFCD00005845
别名 腺苷-3'，5'-环磷酸 ;Cyclic adenosine monophosphate; Adenosine cyclic 3',5'-monophosphate; NSC 143670; NSC 94017; Adenosine Cyclophosphate; cAMP
运输蓝冰
InChI Key IVOMOUWHDPKRLL-KQYNXXCUSA-N
Pubchem ID 6076
存储条件

In solvent -20°C: 3-6个月 -80°C: 12个月

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C
溶解方案

H2O: 2 mg/mL(6.08 mM)，配合低频超声助溶

0.1 M NaOH: 30 mg/mL(91.13 mM)，配合低频超声，并调节pH至6

Tags: Cyclic AMP | Cyclic adenosine monophosphate;Adenosine cyclic 3', 5'-monophosphate;NSC 143670;NSC 94017;Adenosine 3',5'-cyclic monophosphate;Adenosine Cyclophosphate;cAMP | 腺苷-3'，5'-环磷酸 | AmBeed-信号通路专用抑制剂 | Cyclic AMP/环磷腺苷 纯度/质量文件 | Cyclic AMP/环磷腺苷 生物活性 | Cyclic AMP/环磷腺苷 临床数据 | Cyclic AMP/环磷腺苷 参考文献 | Cyclic AMP/环磷腺苷 实验方案 | Cyclic AMP/环磷腺苷 技术信息

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