货号:A2926496
同义名:
重组生物素化人LILRB3蛋白(C-Fc-Avi, HEK293)
/ Biotinylated Human LILRB3 (C-Fc-Avi, HEK293); Leukocyte immunoglobulin-like receptor subfamily B member 3
Biotinylated Human LILRB3 (C-Fc-Avi, HEK293) 是人源蛋白,采用HEK293细胞表达系统表达,带有C端Fc和Avi标签。它是白细胞免疫球蛋白样受体亚家族B成员3,属于具有抑制功能的免疫调节受体,含有ITIM结构域,可通过未明确机制在脱颗粒时从胞膜释放,可能调控中性粒细胞成熟与早期活化,适用于免疫研究与检测应用。


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| 描述 | Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) is a member of Leukocyte Immunoglobulin-Like Receptors family, and there are 11 receptors that have two to four extracellular Ig-like domains, and are categorized as inhibitory or activating. The inhibitory receptors (LILRB1 to B5) possess long cytoplasmic tails containing ITIMs, whilst the activating receptors (LILRA1 to A6, excluding A3) possess short cytoplasmic tails and couple with ITAM-bearing FcεRIγ.ILRB3 is ITIM-bearing, whilst LILRA6 associates with FcRγ. LILRB3 is released from the surface through an uncharacterized mechanism upon degranulation, This raises the possibility that LILRB3 modulates the maturation and/or early activation of neutrophils. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-Fc-Avi |
| 蛋白表达区间 | Gly24-Glu443 |
| 蛋白编号 | O75022-1 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 74.8 KDa |
| SMILES Code | NONE |
| 别名 | 重组生物素化人LILRB3蛋白(C-Fc-Avi, HEK293) ;Biotinylated Human LILRB3 (C-Fc-Avi, HEK293); Leukocyte immunoglobulin-like receptor subfamily B member 3; LILRB3; CD85 antigen-like family member A; Monocyte inhibitory receptor HL9; CD85a; ILT5; LIR3 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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