Biotinylated Human LILRB3 (C-Fc-Avi, HEK293)
产品说明书
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同义名 : | 重组生物素化人LILRB3蛋白(C-Fc-Avi, HEK293) ;Biotinylated Human LILRB3 (C-Fc-Avi, HEK293); Leukocyte immunoglobulin-like receptor subfamily B member 3; LILRB3; CD85 antigen-like family member A; Monocyte inhibitory receptor HL9; CD85a; ILT5; LIR3 |
| CAS号 : | N/A | |
| 货号 : | A2926496 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 74.8 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) is a member of Leukocyte Immunoglobulin-Like Receptors family, and there are 11 receptors that have two to four extracellular Ig-like domains, and are categorized as inhibitory or activating. The inhibitory receptors (LILRB1 to B5) possess long cytoplasmic tails containing ITIMs, whilst the activating receptors (LILRA1 to A6, excluding A3) possess short cytoplasmic tails and couple with ITAM-bearing FcεRIγ.ILRB3 is ITIM-bearing, whilst LILRA6 associates with FcRγ. LILRB3 is released from the surface through an uncharacterized mechanism upon degranulation, This raises the possibility that LILRB3 modulates the maturation and/or early activation of neutrophils. | ||