6-Aminopenicillanic acid/6-氨基青霉烷酸
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货号：A141395
同义名：
6-APA; NSC 50071
6-APA是青霉素类药物的核心部分。
6-Aminopenicillanic acid/6-氨基青霉烷酸 化学结构
6-Aminopenicillanic acid/6-氨基青霉烷酸 3D分子结构
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6-Aminopenicillanic acid/6-氨基青霉烷酸 纯度/质量文件 产品仅供科研
货号：A141395
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• Science , 2025, 387(6729): eadp5637. Ambeed. • Nat. Electron. , 2025, 8, 66-74. Ambeed. • Nano-Micro Lett. , 2025, 17, 311. Ambeed. • Adv. Mater. , 2025, 2416621. Ambeed. • Adv. Mater. , 2025, 2410493. Ambeed. 更多 >
6-Aminopenicillanic acid/6-氨基青霉烷酸 质控信息
6-Aminopenicillanic acid/6-氨基青霉烷酸 生物活性
描述
6-APA (6-aminopenicillanic acid), is used to prepare raw materials for semi synthetic penicillin. In the fermentation broth of P. chrysogenum it is necessary to distinguish between the primary 6-APA which is a product of the biosynthesis via L-cystine/D-valine and the secondary 6-APA which originates from isopenicillin N[2] [3] [4] [5]
6-Aminopenicillanic acid/6-氨基青霉烷酸 参考文献
[1] Batchelor FR, Doyle FP, et al. Synthesis of penicillin: 6-aminopenicillanic acid in penicillin fermentations. Nature. 1959 Jan 24;183(4656):257-8.
[2] Bosnic P, Gelineo A, Gajic B. Biogenez 6-aminopenitsillanovoĭ kisloty (6-APK) i penitsillina u Penicillium chrysogenum; éffekt biokatalizatora khrizina [Biogenesis of 6-aminopenicillanic acid (6-APA) and penicillin in Penicillium chrysogenum: effect of the biocatalyst chrysin]. Antibiot Khimioter. 1994;39(9-10):6–11
[3] Arshad R, Farooq S, Ali SS. 6-aminopenicillanic acid production by intact cells of E. coli containing penicillin G acylase (PGA). Pak J Biol Sci. 2007;10(18):3190–3194
[4] Yoshida M, Koeda T. Effects of aminobenzyl penicillin (AB-PC), methylchlorophenyl isoxazolyl penicillin (MCI-PC) and 6-aminopenicillanic acid (6-APA) on the contractile response of guinea-pig urinary bladder. Nihon Heikatsukin Gakkai Zasshi. 1984;20(1):1–12
[5] Lorian V, Atkinson B. Comparison of the effects of mecillinam and 6-aminopenicillanic acid on Proteus mirabilis, Escherichia coli, and Staphylococcus aureus. Antimicrob Agents Chemother. 1977;11(3):541–552
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6-Aminopenicillanic acid/6-氨基青霉烷酸 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
4.62mL
0.92mL
0.46mL
23.12mL
4.62mL
2.31mL
46.24mL
9.25mL
4.62mL
6-Aminopenicillanic acid/6-氨基青霉烷酸 技术信息
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