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货号 产品名 纯度
A1937088 现货 JB002

JB002是一种肌球蛋白 II 抑制剂,IC50 ≤ 10 μM,适用于肌肉痉挛、慢性肌肉骨骼疼痛及肥厚型心肌病的研究。

99%+
A1553747 现货 Pentachloropseudilin

Pentachloropseudilin是一种可逆的肌球蛋白 (Myo1s) 抑制剂,对I类肌球蛋白的IC50为1-5 μM,能够有效抑制TGF-β诱导的信号传导。

98%
A320082 现货 BTS/N-苄基对甲苯磺酰胺

BTS is a potent and selective inhibitor of Ca2+-stimulated myosin S1 ATPase with IC50 value of ~5 µM.

98%
A1496581 现货 Aficamten

Aficamten is a cardiac myosin allosteric inhibitor.

98% 98.68% ee
A439969 现货 ML-9

ML 9 a is myosin light chain kinase (MLCK) inhibitor. ML-9 enhances the anticancer activity of docetaxel, suggesting its potential application as an adjuvant to existing anticancer chemotherapy. The complex effect of ML-9 on autophagy and indentified ML-9 as an attractive tool for targeting autophagy in cancer therapy through dual inhibition of both the Akt pathway and the autophagy.

99%+
A409555 现货 Mavacamten

MYK-461 is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy, and can reduce contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.

99%
A408772 现货 Omecamtiv mecarbil

Omecamtiv mecarbil is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.

99%+
A182285 现货 (-)-Blebbistatin/(-)-布雷他汀

(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM​).

99%+
A1883217 现货 JB062

JB062是一种非肌肉肌球蛋白抑制剂,对骨骼肌、心肌和平滑肌肌球蛋白的选择性较强,能够有效抑制肿瘤细胞生长而不损伤正常细胞。JB062 适用于肌肉痉挛、慢性肌肉骨骼疼痛以及肥厚型心肌病的研究,具有潜在的治疗价值。

99%+
A1806879 Para-aminoblebbistatin

98%
A1810760 16-38-Thymosin β4 (cattle)

98%
A2791632 JB002

99%
A1496979 Phenamacril

A782981 ATM-3507

ATM-3507 is a potent tropomyosin inhibitor with IC50s from 3.83-6.84 μM in human melanoma cell lines.

98%
A1177103 para-Nitroblebbistatin

A1553120 ATM-3507 3HCl

98%
A1551753 MT-134

98%
A1810576 MPH-220

98%
A1942381 Sevasemten

98%
A1997122 JB061

98%
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