IMT1 是一种首创的、特异性和非竞争性的人线粒体 RNA 聚合酶 (POLRMT) 抑制剂。IMT1 在线粒体转录相关疾病的研究中具有潜在应用。

MFI8是一种线粒体融合的小分子抑制剂。

MSDC-0160 is a prototype mTOR-modulating insulin sensitizer being studied to treat diabetes and Alzheimer's disease.

Azoramide is a modulator of the unfolded protein response (UPR) with antidiabetic activity.

Mitochondrial Fusion Promoter M1 induces mitochondrial elongation and promotes mitochondrial fusion in mammalian cells.

Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis.

MCU i4 is a negative modulator of mitochondrial calcium (Ca²⁺) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca²⁺ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential.

TRO19622, a small cholesterol-like molecule, is a neuroregenerative and neuroprotective compound.