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货号 产品名 纯度
A759879 现货 Pristimerin

Pristimerin是一种高效的单甘油脂肪酶 (MGL) 可逆抑制剂,IC50 为 93 nM。

99%
A432263 现货 JW 642

JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.

99%+
A853152 现货 JJKK 048

JJKK 048 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 0.4 nM.

98%+
A644717 现货 Ibrolipim

Ibrolipim is a Lipoprotein lipase activator.

99%+
A1226769 现货 RHC 80267

RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways.

99%+
A215224 现货 KML29

KML29 is a highly selective and potent MAGL inhibitor with IC50s for 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively.

98%
A153051 现货 H-Phe(4-Ac)-OH/4-乙酰基-L-苯丙氨酸

99%+
A1481148 现货 DB2313

DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.

98%+
A1193393 现货 MJN110

98%
A1549735 现货 AA38-3

99%+
A1210781 现货 Lalistat 2

97%
A866363 现货 Elcubragistat

ABX-1431 works as both a cannabinoid receptor agonist and a MAGL inhibitor.

99%+
A513618 现货 JZL184

JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.

98%
A1364870 现货 JNJ-42226314

98%
A328422 现货 LCL521 2HCl/LCL521二盐酸盐

LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted.

98%
A241114 现货 Atglistatin

Atglistatin is a potent, selective and competitive ATGL with IC50 value of 0.7 μM.

99%+
A885460 现货 XEN445

XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.

99%+
A512085 现货 Orlistat/奥利司他

Orlistat is an approved reversible general lipase inhibitor with IC50 of 122 ng/mL, used to treat obesity.

98%
A117014 现货 Cetilistat/新利司他

Cetilistat is a novel pancreatic lipase used to treat obesity.

98%
A1209509 现货 MAGL-IN-5

97%
产品名 Lipase 其他靶点 纯度
XEN445 +++

endothelial lipase, IC50: 0.237 μM

99%+
JZL184 ++++

MAGL, IC50: 8 nM

98%
Tanshinone IIA 97%
Orlistat 98%
Atglistatin ++

ATGL, IC50: 0.7 μM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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