Fluxametamide 是一种广谱杀虫剂和 GABA 及谷氨酸门控氯离子通道拮抗剂，其对 M. domestica 中的 GABACl 和 GluCl 的 IC50 值分别为 1.95 nM 和 225 nM。

Carbaryl is an acetylcholinesterase inhibitor with IC50 of 13.6 nM for A. gambiae AChE2 expressed in Sf9 cells and Ki of 5.7 µM for rat brain AChE, it's a carbamate insecticide.

Nitenpyram is a nAchR agonist, used an antiparasitic drug.

Dinotefuran is the third generation of neonicotinoid group,which works through inhibiting nAchRs.

Emamectin benzoate acts as an activator of chloride channel via binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels. It can disrupt nerve signals in arthropods.

Furilazole is a pesticide agent.

Scopine HCl salt is a naturally occuring α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock and also s a potential brain-targeting moiety for enhancing the brain uptake efficiency of chlorambucil.

2-Methyl-3,5-Dinitrobenzamide is a fodder additive for poultry, used to prevent coccidiosis infections.

Dicyclanil is an insect growth regulator compound with a similar chemical structure to cyromazine .

Ethyl Carbamate is natural product formed in alcoholic beverages and fermented foods during fermentation process and/or during storage, classified as a probable human carcinogen (Group 2A).