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货号 产品名 纯度
A269967 α-L-Rhamnose monohydrate/α-L-鼠李糖一水合物

L-Rhamnose, a natural product isolated and purified from the flowers of Scphora japonica L., increases serum propionate after long-term supplementation, but lactulose does not raise serum acetate, has anticancer potential, they exert a significant suppressive effect on tumour growth, and exhibits potent excellent sodium-glucose transporter (SGLT1 and SGLT2) inhibition activity.

98%
A225622 Sotagliflozin

LX4211 is an inhibitor of SGLT2 and SGLT1 with antidiabetic activity.

98%
A1006406 Ertugliflozin L-pyroglutamic acid

Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2].

99%
A245799 Ipragliflozin (L-Proline)

Ipragliflozin (L-Proline) selectively inhibits SGLT2 with IC50 of 2.8 nM.

98%
A187149 Bexagliflozin

Bexagliflozin is an inhibitor of SGLT2 with IC50 value of 2 nM.

99%+
A671271 Trilobatin/三叶甙

Trilobatin, a natural product isolated and purified from the herbs of Lithocarpus pachyphyllus with anti-oxidant effect, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway and is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.

99%+
A247239 Canagliflozin hemihydrate/坎格列净半水合物

Canagliflozin selectively inhibits SGLT2 with IC50 of 2.2 nM.

98%
A170374 Phloretin/根皮素

Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree.

98%
A297470 Remogliflozin etabonate

97%
A145381 Dapagliflozin impurity/达格列净杂质

99%+
A1231619 O-Desethyl Dapagliflozin

95%
A1167800 Mizagliflozin

98%
A1339527 KGA-2727

98%
A136380 Ipragliflozin/伊格列净

Ipragliflozin is a selective inhibitor of SGLT2 with IC50 of 14 nM for hSGLT2.

98%
A237947 Licogliflozin

Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor

98%+
A112500 Empagliflozin/恩格列净

Empagliflozin is a selective inhibitor of SGLT-2 with IC50 of 3.1 nM.

98%
A335983 Canagliflozin/卡格列净

Canagliflozin is a novel C-glucoside with thiophene ring.

95%
A163609 Phlorizin/根皮苷

Phlorizin is an inhibitor of hSGLT1 (Ki=300 nM) and hSGLT2 (Ki= 39 nM). It can be found in a number of fruit trees.

98%
A566836 Tofogliflozin (hydrate)

Tofogliflozin is a potent and highly specific sodium/glucose cotransporter 2(SGLT2) inhibitor with Ki values of 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2.

99%+
A120381 Dapagliflozin/达格列净

Dapagliflozin is a selective inhibitor of SGLT2 with EC50 of 1.1 nM which is used to treat type 2 diabetes mellitus.

97%
产品名 SGLT1 SGLT2 其他靶点 纯度
Phloretin 98%
Canagliflozin +++

mSGLT2, IC50: 2 nM

hSGLT2, IC50: 3.7 nM

95%
Empagliflozin ++

SGLT2, IC50: 3.1 nM

98%
Dapagliflozin ++++

hSGLT2, EC50: 1.1 nM

97%
Tofogliflozin (hydrate) +++

hSGLT2, IC50: 2.9 nM

99%+
Sotagliflozin +

SGLT1, IC50: 36 nM

++++

SGLT2, IC50: 1.8 nM

98%
Ipragliflozin ++

hSGLT2, IC50: 7.4 nM

98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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