Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion, while glycosylated prolactin is reported to be constitutively secreted, have lower biological potency, and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals, where secretion is under tonic inhibition by hypothalamic dopamine. In humans, prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy, but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity, peripherally produced prolactin plays roles in breast and prostate cancer development, regulation of reproductive function, and immunoregulation.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His) 技术信息
CAS号
N/A
分子量
23.5 KDa
SMILES Code
NONE
别名
重组羊PRL蛋白(HEK293, C-6His)
;Recombinant Sheep PRL (C-6His); Prolactin; PRL
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His)
|Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His)
| 重组羊PRL蛋白(HEK293, C-6His)
| Recombinant Sheep PRL (C-6His)
| Prolactin
| PRL
| N/A
| Peptide Hormone & Neuropeptides
| Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His) 纯度/质量文件
| Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His) 生物活性
| Sheep PRL (C-6His)/羊PRL蛋白(HEK293, C-6His) 技术信息
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