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Sarafloxacin HCl/沙拉沙星盐酸盐
Sarafloxacin HCl/沙拉沙星盐酸盐
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货号：A129788
同义名：
盐酸沙拉沙星
/ A-56620 hydrochloride; Sarafloxacin hydrochloride
Sarafloxacin HCl是一种兽用氟喹诺酮类抗生素，IC50 为 0.96 μg/L，可抑制细菌 DNA 旋转酶。
Sarafloxacin HCl/沙拉沙星盐酸盐 化学结构
Sarafloxacin HCl/沙拉沙星盐酸盐 3D分子结构
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Sarafloxacin HCl/沙拉沙星盐酸盐 纯度/质量文件 产品仅供科研
货号：A129788
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Sarafloxacin HCl/沙拉沙星盐酸盐 质控信息
Sarafloxacin HCl/沙拉沙星盐酸盐 生物活性
描述
Sarafloxacin Hydrochloride is a quinolone antibiotic drug. The inhibitory level of sarafloxacin for the tested bacteria was strain dependent. It appeared that in broth culture Escherichia coli isolates were sensitive to sarafloxacin concentrations 5-fold lower than the concentrations present in the simulated gut model, suggesting that sarafloxacin may be partially unavailable due to absorption to organic matter in the model[3] [4]
Sarafloxacin HCl/沙拉沙星盐酸盐 参考文献
[1] Liu YZ, Zhao GX, et al. Production of the broad specific monoclonal antibody against sarafloxacin for rapid immunoscreening of 12 fluoroquinolones in meat. J Environ Sci Health B. 2013;48(2):139-46.
[2] McConville ML, Dijkstra JW, et al. Effects of sarafloxacin hydrochloride on human enteric bacteria under simulated human gut conditions. Vet Q. 1995 Mar;17(1):1-5.
[3] McConville ML, Dijkstra JW, Stamm JM, van Saene JJ, Nouws JF. Effects of sarafloxacin hydrochloride on human enteric bacteria under simulated human gut conditions. Vet Q. 1995 Mar;17(1):1-5.
[4] Fang X, Zhou J, Liu X. Pharmacokinetics of sarafloxacin in allogynogenetic silver crucian carp, Carassius auratus gibelio. Fish Physiol Biochem. 2016 Feb;42(1):335-41.
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Sarafloxacin HCl/沙拉沙星盐酸盐 实验方案
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存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.37mL
0.47mL
0.24mL
11.85mL
2.37mL
1.19mL
23.71mL
4.74mL
2.37mL
Sarafloxacin HCl/沙拉沙星盐酸盐 技术信息
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