货号:A2926336
同义名:
重组恒河猴BAFF蛋白(N-Fc, HEK293)
/ Recombinant Rhesus Macaque BAFF (N-Fc, HEK293); TNF superfamily member 13b
Recombinant Rhesus Macaque BAFF (N-Fc, HEK293)是来自恒河猴的重组BAFF蛋白,在HEK293人源细胞中表达,带有N端Fc标签。该蛋白又称TNFSF13B,也被称为B细胞激活因子(BAFF)、BLyS,属于TNF配体超家族,参与局部和系统性炎症网络,与严重HAdV肺炎、BVVL、肌萎缩侧索硬化及RA、MS等免疫相关疾病的发生发展密切相关。


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| 描述 | TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules in local and systemic inflammatory network, and the plasma TNFSF13B and TNFSF14 may be the potential local and systemic inflammatory indicators of severe HAdV pneumonia in pediatric patients. Identification of TNFSF13B as candidate causative genes supports conjectures on involvement of the immune system in BVVL and amyotrophic lateral sclerosis. It’s reported that APRIL, BAFF, and BAFF receptors play a major role in the pathogenesis of RA, and MSCT seems to inhibit these immunological factors. |
| 蛋白种属 | Rhesus macaque |
| 表达系统 | Human Cells |
| 标签 | N-Fc |
| 蛋白表达区间 | Ala134-Leu285 |
| 蛋白编号 | F7HHH0 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 42.9 kDa |
| SMILES Code | NONE |
| 别名 | 重组恒河猴BAFF蛋白(N-Fc, HEK293) ;Recombinant Rhesus Macaque BAFF (N-Fc, HEK293); TNF superfamily member 13b; TNFSF13B; Tumor necrosis factor ligand 7A; TNLG7A |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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