货号:A2900807
同义名:
重组小鼠ST2蛋白(HEK293, C-6His)
/ Recombinant Mouse ST2 (C-6His)
Recombinant Mouse ST2 (C-6His)由哺乳动物表达系统生产,目标基因编码Ser27-Ala337,并在C末端带有6His标签。
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描述 | 产品名称:Recombinant Mouse ST2 (C-6His)理论分子量:36.6 KDa蛋白种属:Mouse表达系统:Human Cells蛋白表达区间:Ser27-Ala337标签:C-6His剂型:干粉纯度:≥95% as determined by reducing SDS-PAGE.储存条件:冻干蛋白应储存在≤-20°C,收到后可稳定保存一年。 溶解后的蛋白溶液可以在2-8°C下保存2-7天。如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。产品背景:ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity. |
CAS号 | N/A |
分子量 | 36.6 KDa |
SMILES Code | NONE |
别名 | 重组小鼠ST2蛋白(HEK293, C-6His) ;Recombinant Mouse ST2 (C-6His) |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry, store in freezer, under -20°C |