Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free)
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货号：A2900792同义名：
重组小鼠IL-22蛋白(E.coli, tag free)
/ Recombinant Mouse IL-22 (E. coli); Interleukin-22
Recombinant Mouse IL-22 (E. coli)是小鼠来源的重组蛋白，在大肠杆菌中表达，为无标签蛋白。该蛋白为白细胞介素-22，成熟体含147个氨基酸，与人和小鼠同源蛋白分别有约79%和22%序列同源性，可激活STAT-1和STAT-3，上调急性期蛋白产生，参与炎症反应，其功能受体由IL-22R和IL-10Rβ组成。
Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free) 化学结构 CAS号：N/A
Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free) 3D分子结构 CAS号：N/A
Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free) 质控信息
Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free) 生物活性
描述
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Mouse IL-22 (E. coli)/小鼠IL-22蛋白(E.coli, tag free) 技术信息
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