The glucagon receptor (GCGR), a class B G protein-coupled receptor (GPCR), is the principal regulator of glucagon action in the liver. Glucagon receptor (Gcgr) plays a key role in regulating both glucose and lipid metabolisms. Glucagon is a linear peptide containing 29 amino acids. It is secreted by islet α cells and mainly targets the liver cells. After glucagon specifically binds to GCGR, it promotes liver glycogen breakdown and increases blood glucose levels to stimulate insulin release.
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 1 个月。
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