Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. FGF-4 is proposed to play a physiologically relevant role in human embryonic stem cell selfrenewal. It promotes stem cell proliferation, but may also aid differentiation depending on context and concentration, and is often included in embryonic stem cell media in vitro. FGF-4 is mitogenic for fibroblasts and endothelial cells in vitro and has autocrine transforming potential. It is a potent angiogenesis promoter in vivo and has been investigated as therapy for coronary artery disease.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
15.2 KDa
SMILES Code
NONE
别名
重组小鼠FGF-4蛋白(E.coli, tag free)
;Recombinant Mouse FGF-4; Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3; FGF4; HST; HSTF1; KS3
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free)
|Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free)
| 重组小鼠FGF-4蛋白(E.coli, tag free)
| Recombinant Mouse FGF-4
| Fibroblast growth factor 4
| FGF-4
| Heparin secretory-transforming protein 1
| HST
| HST-1
| HSTF-1
| Heparin-binding growth factor 4
| HBGF-4
| Transforming protein KS3
| FGF4
| HST
| HSTF1
| KS3
| N/A
| FGF Family
| Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free) 纯度/质量文件
| Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free) 生物活性
| Mouse FGF-4/小鼠FGF-4蛋白(E.coli, tag free) 技术信息
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