货号:A2900707
同义名:
重组小鼠CCL9蛋白(E.coli, tag free)
/ Recombinant Mouse CCL9; C-C motif chemokine 9
Recombinant Mouse CCL9是小鼠来源的重组蛋白,在大肠杆菌中表达,为无标签蛋白。该蛋白即C-C motif chemokine 9,是11 kDa的分泌型单体多肽,属β(或CC)趋化因子家族,主要在肝、肺和胸腺表达,有抗炎、致热及促细胞运动特性,可激活中性粒细胞钙释放,抑制骨髓髓系未成熟祖细胞集落形成,还能通过CCR1激活破骨细胞,参与骨吸收。


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| 描述 | C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption. |
| 蛋白种属 | Mouse |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Gln22-Gln122 |
| 蛋白编号 | P51670 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM His-HCl, 8% Sucrose, 0.05% Tween80, pH5.5. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 11.6 KDa |
| SMILES Code | NONE |
| 别名 | 重组小鼠CCL9蛋白(E.coli, tag free) ;Recombinant Mouse CCL9; C-C motif chemokine 9; CCF18; Macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; Small-inducible cytokine A9; Scya10; Scya9 and CCL9 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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