货号:A2923965
同义名:
重组小鼠CCL24蛋白(Tag free, E.coli)
/ Recombinant Mouse CCL24 (E.coli); C-C motif chemokine 24
Recombinant Mouse CCL24 (E.coli) 是来自小鼠的重组蛋白,在大肠杆菌中表达,为无标签蛋白。该蛋白属于CC趋化因子亚家族,是分泌型蛋白,由119个氨基酸残基组成,与人类Ccl24氨基酸序列相似度约58%。主要在空肠和脾脏中表达,也可被过敏原刺激和IL4诱导在肺中表达,对静息T淋巴细胞、嗜酸性粒细胞具有趋化作用,并可结合CCR3。


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| 描述 | Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages. |
| 蛋白种属 | Mouse |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Val27-Val119 |
| 蛋白编号 | Q9JKC0 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 10.3 KDa |
| SMILES Code | NONE |
| 别名 | 重组小鼠CCL24蛋白(Tag free, E.coli) ;Recombinant Mouse CCL24 (E.coli); C-C motif chemokine 24; Ccl24; Eosinophil chemotactic protein 2; Eotaxin-2; Small-inducible cytokine A24; Scya24 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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