货号:A2926309
同义名:
重组小鼠BTNL6蛋白(C-6His, HEK293)
/ Recombinant Mouse BTNL6 (C-6His, HEK293); BTNL6
Recombinant Mouse BTNL6 (C-6His, HEK293)是小鼠来源的重组Butyrophilin-like 6蛋白,在HEK293人源细胞中表达,带有C端6×His标签。该蛋白属于BTN/MOG免疫球蛋白超家族,与BTNL1形成异源二聚体调控免疫细胞增殖,尤其促进γδ T细胞扩增,与小肠上皮组织T细胞富集相关,体外研究显示其可协同抑制CD3诱导的IL-2分泌。


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| 描述 | Butyrophilin-like 6 (BTNL6) is a member of the BTN/MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) replete with T cells. Our in-house studies showed BTNL6 co-inhibited anti-CD3 induced IL-2 secretion on CD3+ cells. |
| 蛋白种属 | Mouse |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Lys29-Trp249 |
| 蛋白编号 | A2CG22 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Histidine, 6% Trehalose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH6.5. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 25.6 KDa |
| SMILES Code | NONE |
| 别名 | 重组小鼠BTNL6蛋白(C-6His, HEK293) ;Recombinant Mouse BTNL6 (C-6His, HEK293); BTNL6; Gm6519; NG13; Butyrophilin-like 6; EG624681 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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