货号:A775007
同义名:
孟酮
/ p-Menthan-3-one; NSC 9280
Menthone, a natural product isolated and purified from the herbs of Mentha canadensis L., enhances the skin permeability by disordering the ordered organization of SC lipids and extracts part of SC lipids, while pulegone appears to promote drug transport across the skin only by extracting part of SC lipids.
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Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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描述 | Menthone, a natural product isolated and purified from the herbs of Mentha canadensis L., enhances the skin permeability by disordering the ordered organization of SC (stratum corneum) lipids and extracts part of SC lipids, while pulegone appears to promote drug transport across the skin only by extracting part of SC lipids[3]. Vit C and menthone at higher dose have a good compensatory effect with significant reduction in DNA damages in sperm cells by reversing the adverse effect of ACV (Acyclovir) on the reproductive system in male rat[4]. Menthone, a component of peppermint oil, was given p.o. to groups of 10 male and 10 female rats at dose levels of 0, 200, 400 and 800 mg/kg b.w./day, respectively, for 28 days. After 19 days the dose was reduced to 400 mg/kg b.w. in the female group receiving the highest dose. Analyses of plasma showed a dose-dependent decrease in creatinine content and a dose-dependent increase in alkaline phosphatase activity and bilirubin. The relative weights of liver and spleen were increased. Cyst-like spaces were seen histopathologically in the white matter of the cerebellum of the two highest dose groups[5]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT02106403 | Skin Care | Not Applicable | Completed | - | China, Guangdong ... 展开 >> Guangzhou Landproof Testing Technology Co., LTD Guangzhou, Guangdong, China, 510635 收起 << |
NCT03475836 | Cognitive Change ... 展开 >> Affect 收起 << | Not Applicable | Completed | - | - |
NCT02106403 | - | Completed | - | - |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
6.48mL 1.30mL 0.65mL |
32.41mL 6.48mL 3.24mL |
64.83mL 12.97mL 6.48mL |
CAS号 | 10458-14-7 |
分子式 | C10H18O |
分子量 | 154.25 |
SMILES Code | O=C1C(C(C)C)CCC(C)C1 |
MDL No. | MFCD00062998 |
别名 | 孟酮 ;p-Menthan-3-one; NSC 9280; NSC 113134 |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
溶解方案 |
DMSO: 105 mg/mL(680.71 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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