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首页 / 药物研究 / 小分子阳性药 / 其他化合物 / Lactate sodium/DL-乳酸钠

Lactate sodium/DL-乳酸钠 {[allProObj[0].p_purity_real_show]}

货号：A128732 同义名： 2-羟基丙酸钠 / Lactic acid sodium; Lactate(sodium)

Lactate sodium是糖原分解的产物，用作注射液的缓冲剂和 pH 调节剂。它还具有抗菌活性，可用于食品保鲜和医学应用。

Lactate sodium/DL-乳酸钠 化学结构 CAS号：72-17-3
Lactate sodium/DL-乳酸钠 化学结构
CAS号：72-17-3
Lactate sodium/DL-乳酸钠 3D分子结构
CAS号：72-17-3
Lactate sodium/DL-乳酸钠 化学结构 CAS号：72-17-3
Lactate sodium/DL-乳酸钠 3D分子结构 CAS号：72-17-3
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Lactate sodium/DL-乳酸钠 纯度/质量文件 产品仅供科研

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Lactate sodium/DL-乳酸钠 生物活性

描述 Lactate (Lactic acid) sodium is produced as a result of glycogenolysis and glycolysis[1]. This organic salt is primarily utilized as a buffer and pH adjuster in injection solutions. Lactate sodium is metabolizable by the body into sodium bicarbonate, which subsequently raises the blood pH. It is applied in medical treatments to ameliorate conditions like metabolic acidosis and hypovolemic states. In pharmaceutical formulations, Lactate sodium is commonly combined with sodium chloride, glucose, and other substances to create solutions such as normal saline or compound liquid for intravenous injections[2].[3].[4].[5]. Lactate sodium also exhibits antimicrobial properties, making it useful as a food preservative[6].
体外研究

Additionally, hypertonic Lactate sodium solution has been shown to enhance cognitive function in rats suffering from traumatic brain injury (TBI). This solution not only reduces intracranial pressure (ICP) but also boosts cerebral blood flow through the dilation of arterioles[2].[3].

Moreover, Lactate sodium has been found to inhibit the growth of various spoilage microorganisms, including aerobic and psychrophilic bacteria, Pseudomonas, lactic acid bacteria, and Enterobacteriaceae, which underscores its broader antimicrobial efficacy[6].

Lactate sodium/DL-乳酸钠 参考文献

[1]Brooks GA. Lactate: link between glycolytic and oxidative metabolism. Sports Med. 2007;37(4-5):341-3.

[2]Ichai C, et al. Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med. 2009 Mar;35(3):471-9.

[3]Rice AC, et al. Lactate administration attenuates cognitive deficits following traumatic brain injury. Brain Res. 2002 Feb 22;928(1-2):156-9.

[4]Hospira, Inc. (November 2004). "Sodium Lactate (sodium lactate) Injection, Solution, Concentrate". DailyMed. U.S. National Library of Medicine. Archived from the original on 2014-01-04. Retrieved 2012-08-16.

[5]Forsythe SM, et al. Sodium bicarbonate for the treatment of lactic acidosis. Chest. 2000 Jan;117(1):260-7.

[6]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18(5):566-575.

Lactate sodium/DL-乳酸钠 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

8.92mL

1.78mL

0.89mL

44.62mL

8.92mL

4.46mL

89.24mL

17.85mL

8.92mL

Lactate sodium/DL-乳酸钠 技术信息

CAS号72-17-3
分子式C3H5NaO3
分子量 112.06
SMILES Code CC(O)C([O-])=O.[Na+]
MDL No. MFCD00065400
别名 2-羟基丙酸钠 ;Lactic acid sodium; Lactate(sodium)
运输蓝冰
InChI Key NGSFWBMYFKHRBD-UHFFFAOYSA-M
Pubchem ID 23666456
存储条件

In solvent -20°C:3-6个月-80°C:12个月
溶解方案

DMSO: 105 mg/mL(937 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 150 mg/mL(1338.57 mM)

Tags: Lactate sodium | Lactic acid sodium | 2-羟基丙酸钠 | Other Compounds | AmBeed-信号通路专用抑制剂 | Lactate sodium/DL-乳酸钠 纯度/质量文件 | Lactate sodium/DL-乳酸钠 生物活性 | Lactate sodium/DL-乳酸钠 参考文献 | Lactate sodium/DL-乳酸钠 实验方案 | Lactate sodium/DL-乳酸钠 技术信息

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