货号:A2900890
同义名:
重组人sCD4蛋白(HEK293, C-6His)
/ Recombinant Human sCD4 (C-6His)
Recombinant Human sCD4 (C-6His)由哺乳动物表达系统生产,目标基因编码Lys26-Trp390,并在C末端带有6His标签。
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描述 | 产品名称:Recombinant Human sCD4 (C-6His)理论分子量:41.7 KDa蛋白种属:Human表达系统:Human Cells蛋白表达区间:Lys26-Trp390标签:C-6His剂型:干粉纯度:≥95% as determined by reducing SDS-PAGE.储存条件:冻干蛋白应储存在≤-20°C,收到后可稳定保存一年。 溶解后的蛋白溶液可以在2-8°C下保存2-7天。如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。产品背景:CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations. Mature human CD4 consists of a 371 amino acid extracellular region containing four immunoglobulin-like domains, a 22 aa transmembrane segment, and a 40 aa cytoplasmic domain. CD4 is expressed along with CD8 on double positive T cells during their development in the thymus. CD4 binds directly to MHC class II molecules on antigen presenting cells (10). This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction. CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a co-receptor for the gp120 surface glycoprotein of HIV-1. |
CAS号 | N/A |
分子量 | 41.7 KDa |
SMILES Code | NONE |
别名 | 重组人sCD4蛋白(HEK293, C-6His) ;Recombinant Human sCD4 (C-6His) |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry, store in freezer, under -20°C |