Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 质控信息
Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 生物活性
描述
WAP Four-Disulfide Core Domain Protein 2 (WFDC2) is a 25 kDa secreted glycoprotein containing two WAP domains. Mature human WFDC2 is 94 amino acids (aa) in length. It contains two WAP domains that likely mediate antiprotease and/or antimicrobial activity (aa 31 - 73 and 74 - 123). There are four potential splice variants. One shows a deletion of aa 27-74, while three others show aa substitutions: 28 aa for aa 75-124, 23 aa for aa 1 - 74, and 10 aa for aa 71-124. WFDC2 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed by a wide variety of epithelial cells, including respiratory epithelium, salivary gland mucous cells, breast duct epithelium, distal tubule renal epithelium, and epididymal epithelium. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
11.07 KDa
SMILES Code
NONE
别名
重组人WFDC2蛋白(C-6His, HEK293)
;Recombinant Human WFDC2 (C-6His, HEK293); WAP Four-Disulfide Core Domain Protein 2; Epididymal Secretory Protein E4; Major Epididymis-Specific Protein E4; Putative Protease Inhibitor WAP5; WFDC2; HE4; WAP5
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293)
|Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293)
| 重组人WFDC2蛋白(C-6His, HEK293)
| Recombinant Human WFDC2 (C-6His, HEK293)
| WAP Four-Disulfide Core Domain Protein 2
| Epididymal Secretory Protein E4
| Major Epididymis-Specific Protein E4
| Putative Protease Inhibitor WAP5
| WFDC2
| HE4
| WAP5
| N/A
| 胰腺肿瘤
| 子宫内膜肿瘤
| 卵巢肿瘤
| 血液肿瘤
| 肺肿瘤
| Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 纯度/质量文件
| Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 生物活性
| Human WFDC2 (C-6His, HEK293)/人WFDC2蛋白(C-6His, HEK293) 技术信息
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