货号:A2900884
同义名:
重组人Uteroglobin蛋白(HEK293, C-6His)
/ Recombinant Human Uteroglobin (C-6His); Uteroglobin
Recombinant Human Uteroglobin (C-6His)由哺乳动物表达系统生产,目标基因编码Glu22-Asn91,并在C末端带有6His标签。
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描述 | Uteroglobin is a small, non-glycosylated secreted protein of the secretoglobin superfamily. It is produced by the non-ciliated, non-mucous secretory cells that predominate in lung bronchioles (Clara cells), and other non-ciliated epithelia that communicate with the external environment. Expression is induced by steroid hormones such as estrogen, and enhanced by the non-steroid hormone prolactin. Human Uteroglobin cDNA encodes a 21 amino acid (aa) signal sequence and a 70 aa mature protein. The mature protein forms a disulfide-linked head-to-tail homodimer of 16 kDa. This homodimer is thought to form a binding pocket that binds hydrophobic ligands such as phospholipids, progesterone and retinols. Binding of fibronectin to Uteroglobin in the kidney is thought to protect against nephropathy, while binding of the lipocalin-1 receptor has been reported to suppress cancer cell motility and invasion. |
蛋白种属 | Human |
表达系统 | Human Cells |
标签 | C-6His |
蛋白表达区间 | Glu22-Asn91 |
蛋白编号 | P11684 |
内毒素 | < 1 EU/µg as determined by LAL test. |
剂型 | 干粉 |
剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
CAS号 | N/A |
分子量 | 8.7 KDa |
SMILES Code | NONE |
别名 | 重组人Uteroglobin蛋白(HEK293, C-6His) ;Recombinant Human Uteroglobin (C-6His); Uteroglobin; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1; SCGB1A1; CCSP; UGB |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |